Dialysis

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 43

Special Issue Editors


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Guest Editor
Nephrology Dialysis and Transplant Unit, Azienda Ospedaliero—Universitaria di Modena, Modena, Italy
Interests: CKD; dialysis; COVID-19; kidney transplantation; HIV; anemia
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Guest Editor
1. Department of Medicine, University of Verona, 37129 Verona, Italy
2. Nephrology and Dialysis Unit, Pederzoli Hospital, 37019 Verona, Italy
Interests: fabry disease; physical exercise in kidney disease; ultrasound imaging in kidney disease
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Dialysis, introduced in the early 20th century, has long been the primary treatment for kidney failure, with peritoneal dialysis (PD) introduced in the 1920s and hemodialysis (HD) in the 1940s. Globally, more than 80% of dialysis patients undergo HD, while home dialysis, including PD and home HD (HHD), is less widely available, although great efforts continue to be made to expand this technique’s use.

Despite advances, mortality rates for dialysis patients remain disproportionately high due to cardiovascular events and infections. Patients on dialysis have a much higher mortality rate than people of the same age and sex in the general population. The death rate for those with treated kidney failure is higher than for many types of cancer. While some studies have suggested that PD offers better survival rates than HD, large-scale observational studies have found no significant difference between the two modalities. In addition to high mortality, dialysis patients face significant challenges, such as frequent hospitalizations, inability to work, and loss of independent living. Health-related quality of life remains poor, with issues like depression, high symptom burden, and the demanding nature of dialysis treatment contributing to this decline.

The growing global burden of kidney failure, driven by aging populations and rising rates of diabetes and hypertension, poses significant challenges to healthcare systems. To address these issues, innovations in dialysis treatment are essential to ensure that future dialysis therapies offer improved quality of life and better outcomes for patients.

The goal of this Special Issue is to gather research studies focused on the current challenges faced by dialysis patients, explore the benefits of home dialysis innovations, and investigate advancements (e.g., new-dialyzer membranes, dialysate regeneration systems, implantable artificial kidney systems) that can enhance patients’ quality of life.

Dr. Gaetano Alfano
Dr. Yuri Battaglia
Guest Editors

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Keywords

  • hemodialysis
  • hemodiafiltration
  • peritoneal dialysis
  • home hemodialysis
  • incremental dialysis
  • dialyzer membrane
  • vascular access
  • dialysis adequacy
  • cardiovascular disease
  • infection
  • symptoms in dialysis
  • mineral bone disease
  • inflammation
  • anemia
  • frailty
  • quality of life

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