Therapeutic Potential of Natural Products in the Treatment of Nervous System Diseases
A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Natural Products".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 86
Special Issue Editor
Interests: neurodegenerative diseases; pain; anxiety; depression
Special Issue Information
Dear Colleagues,
The nervous system is the most complex system of the human body, with a variety of functions still being unclear. “Nervous system diseases” are often referred to as an umbrella term for multiple disorders affecting either the peripheral nervous system, spinal cord or brain, such as neurodegenerative diseases, neurovascular disorders (e.g., hemorrhages, stroke), infections (e.g., meningitis, encephalitis), neuropsychiatric disorders (e.g., depression, schizophrenia), structural disorders (e.g., brain or spinal cord injuries) or conditions such as trigeminal neuralgia, sciatica, migraines, epilepsy, etc. Generally speaking, the pathophysiology of these diseases is often very complex and largely unknown. Taking neurodegenerative diseases as an example, they are mainly caused by the selective dysfunction and progressive degeneration of neurons, glial cells, synapses and the interconnected networks. Currently, the available therapeutic options provide only symptomatic relief rather than halting the disease progression, while also frequently being associated with several adverse effects. Therefore, it is essential to seek new therapeutic strategies to treat these diseases.
Natural products are a rich sources of novel drugs, either through direct use in treating diseases or providing lead compounds for the developing candidate drugs. For example, the widely used neurological drugs morphine, cannabidiol and huperzine A all initially originated from natural products. Hence, natural products may provide an important approach in treating nervous system diseases. In this Special Issue, we invite researchers in the field highlighting the therapeutic potential of natural products to identify future directions that will lead to discoveries and alternative therapies for nervous system diseases. We look forward to receiving your contributions.
Dr. Zhen Tian
Guest Editor
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Keywords
- natural products
- nervous system diseases
- drug discovery
- neurodegeneration
- neuroinflammation
- chronic pain
- neuropsychiatric disorders
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