Recent Advancements in Radiochemistry and PET Radiotracer Development: 2nd Edition

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Radiopharmaceutical Sciences".

Deadline for manuscript submissions: 25 February 2025 | Viewed by 28

Special Issue Editors


E-Mail Website1 Website2
Guest Editor
1. PET Science Centre, Precision Medicine and Biosamples, Oncology R&D, AstraZeneca, Karolinska Institutet, SE-17176 Stockholm, Sweden
2. Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet and Stockholm County Council, SE-17176 Stockholm, Sweden
Interests: PET; radiochemistry; automation; radioligand; drug discovery
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, 17164 Stockholm, Sweden
Interests: PET; radioligand; neuroscience
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Positron Emission Tomography (PET) is a valuable imaging technique used in various applications, including clinical diagnosis, drug discovery, and neuroscience research. PET relies upon the administration of a chemical probe, also known as a radiotracer, which is labelled with a short-lived positron-emitting radionuclide (e.g., 11C, 18F, 68Ga, and 89Zr). The development of novel radiotracers requires multiple considerations, and aspects like radionuclide selection, labeling position, metabolic stability, precursor synthesis, radiolabeling procedure, automation, quality control, and regulatory aspects have to be considered.

This Special Issue aims to highlight the latest research on PET radiotracer synthesis and development, and we invite both original research and review articles on the following topics: (1) new radiolabeling strategies and isotopes for radiotracer production; (2) automation and clinical validation; (3) design and synthesis of novel PET radiotracers targeting specific biological processes, e.g., receptors, enzymes, and transporters; (4) strategies to enhance image quality and quantification; and (5) clinical translations and applications of novel PET radiotracers.

Overall, this Special Issue will provide an authoritative and up-to-date resource for researchers, clinicians, and industry professionals seeking to advance PET imaging and its applications in healthcare and biomedical research.

Dr. Kenneth Dahl
Dr. Sangram Nag
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • radiochemistry
  • labeling
  • automation
  • GMP
  • PET
  • radiotracer
  • radioligand
  • radiopharmaceutical
  • drug discovery

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Published Papers

This special issue is now open for submission.
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