Special Issues

Pharmaceuticals publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Strategies in Drug Design and Development of Small Molecules as Therapeutic Agents
edited by
submission deadline 25 Jan 2025 | 6 articles | Viewed by 7191 | Submission Open
(This special issue belongs to the Section Medicinal Chemistry)
Cyclodextrin-Based Drug Delivery System and Its Pharmaceutical and Biomedical Application 2024 submission deadline 25 Jan 2025 | 4 articles | Viewed by 6686 | Submission Open
Keywords: drug delivery; inclusion complexes; polymeric cyclodextrins; nanostructurated carriers; polyrotaxanes; nanosponges; chemical– physical characterization; in vitro/ex vivo/in vivo evaluation; theranostic; regenerative medicine; gene delivery
(This special issue belongs to the Section Pharmaceutical Technology)
Stem Cells and Organoids as Tools for Drug Development
edited by Daniela Omodei
submission deadline 25 Jan 2025 | 2 articles | Viewed by 3347 | Submission Open
Keywords: stem cells; patient-derived cells; iPSCs (induced pluripotent stem cells); organoids; drug development; drug screening; drug toxicity; preclinical and clinical drug research; novel therapeutics; disease modeling; personalized medicine; precision medicine
(This special issue belongs to the Section Biopharmaceuticals)
Sirtuins as Novel Biological Targets for Pharmacological Intervention in Physiology and Pathology submission deadline 25 Jan 2025 | 2 articles | Viewed by 3125 | Submission Open
Keywords: sirtuins; metabolism; cancer; hypoxia; damage recovery; cell death
(This special issue belongs to the Section Pharmacology)
Novel Treatments and Technologies for Retinal Diseases submission deadline 25 Jan 2025 | 2 articles | Viewed by 2601 | Submission Open
Keywords: age-related macular degeneration; diabetic retinopathy; retinal degeneration; novel therapeutics; imaging biomarkers; artificial intelligence; clinical trials
(This special issue belongs to the Section Pharmaceutical Technology)
Drug Candidates for the Treatment of Atopic Dermatitis
edited by
submission deadline 25 Jan 2025 | Viewed by 467 | Submission Open
Keywords: atopic dermatitis; skin barrier; skin disease; house-dust-mite-induced atopic dermatitis; small molecules for atopic dermatitis treatment
(This special issue belongs to the Section Pharmacology)
Medications: Interactions with Diet, Herbs, Dietary Supplements and Probiotics
edited by , María Isabel Valverde Merino and Maria José Zarzuelo Romero
submission deadline 25 Jan 2025 | Viewed by 359 | Submission Open
Keywords: food– drug interactions; dietary supplements; probiotics; herb– drug interaction
(This special issue belongs to the Section Pharmacology)
Management of Pain in Oral Mucositis
edited by and Thomas Chai
submission deadline 25 Jan 2025 | Viewed by 73 | Submission Open
Keywords: oral mucositis; oral pain; pain management; cancer; cancer therapy
(This special issue belongs to the Section Pharmacology)
Recent Advances in the Pharmacology of Serotonin and Its Receptors, 2nd Edition
edited by and Kinga Sałaciak
submission deadline 25 Jan 2025 | Viewed by 72 | Submission Open
Keywords: serotonin; serotonergic system; serotonergic receptors; serotonin neurotransmission; central nervous system; neuropsychiatry; neuropharmacology; peripheral serotonin; gastrointestinal tract; preclinical studies; clinical studies
(This special issue belongs to the Section Pharmacology)
Novel Anti-proliferative Agents, 2nd Edition
edited by
submission deadline 31 Jan 2025 | 3 articles | Viewed by 3504 | Submission Open
Keywords: medicinal chemistry; drug discovery; natural compounds; synthetic compounds; organic synthesis; bioactivity; anticancer drugs; antiproliferative activity
(This special issue belongs to the Section Medicinal Chemistry)
Development of Antibacterial Drugs to Combat Drug-Resistant Bacteria submission deadline 31 Jan 2025 | 2 articles | Viewed by 1919 | Submission Open
Keywords: development of antibacterial drugs; drug-resistant bacteria; antimicrobial resistance; new therapeutic solutions; improvement of existing therapies; nosocomial infections
(This special issue belongs to the Section Pharmacology)
Preparation Technologies and Dissolution Behaviour of Oral Solids
edited by Paul Wan Sia Heng and Natalia Veronica
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1016 | Submission Open
Keywords: granulation; oral solids; dissolution; sustain release; solubility; oral bioavailability
(This special issue belongs to the Section Pharmaceutical Technology)
Osteosarcomas: Treatment Strategies, 2nd Edition
edited by
submission deadline 31 Jan 2025 | Viewed by 185 | Submission Open
Keywords: osteosarcoma; anti-cancer; apoptosis; natural compounds; target; drug
(This special issue belongs to the Section Pharmacology)
Hsp90 Inhibitors: Progress, Challenges, and Opportunities in Drug Discovery and Development submission deadline 31 Jan 2025 | Viewed by 177 | Submission Open
Keywords: Hsp90; drug discovery; synthesis; chaperone; therapeutic potential; cancer treatment; neurodegenerative diseases; infection resistance mechanisms; research advancements; therapeutic development
(This special issue belongs to the Section Medicinal Chemistry)
Small-Molecule Inhibitors for Novel Therapeutics
edited by and Simone Giovannuzzi
submission deadline 31 Jan 2025 | Viewed by 159 | Submission Open
Keywords: small molecules; enzyme inhibition/activation; protein modulation; novel therapeutics; high-throughput screening; target proteins; drug delivery
Innovative Approaches to Radiopharmaceuticals: Advances in Design, Labeling, and Applications
edited by Shvan J. Raheem and
submission deadline 31 Jan 2025 | Viewed by 126 | Submission Open
Keywords: radiochemistry; radiopharmaceutical; radiotracers
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Molecular Mechanisms and Treatment of Brain Cancer: Recent Advances and Future Trends
edited by
submission deadline 31 Jan 2025 | Viewed by 122 | Submission Open
Keywords: brain cancer; molecular mechanism; treatment; diagnosis; in vitro; in vivo; models
(This special issue belongs to the Section Pharmacology)
Natural Products-Assisted Organic Synthesis in Medicinal Chemistry submission deadline 31 Jan 2025 | Viewed by 96 | Submission Open
Keywords: total organic synthesis; preparative methods of natural products; natural carboxylic acids; derivatives of organic carboxylic acids; amino acids; carbonyl derivatives; phenolic compounds; heterocyclic compounds; antioxidant activity; antifungal activity; antimicrobial activity; anti-inflammatory activity; cytotoxicity; anti-cancer activity; ROS activity; DNA damages; structure-activity studies; DFT calculations for synthetic organic products; molecular docking
(This special issue belongs to the Section Medicinal Chemistry)
Bone Disorder Therapeutics: Novel Drug Candidates and Treatment Strategies
edited by
submission deadline 31 Jan 2025 | Viewed by 95 | Submission Open
Keywords: bone health; osteoporosis; arthritis; osteoarthritis; bone cancer; regeneration; repair; metabolism; gene therapy; cell therapy
(This special issue belongs to the Section Pharmacology)
Therapeutic Targets and Therapies for the Treatment of Oral Cancer and Oral Diseases submission deadline 31 Jan 2025 | Viewed by 90 | Submission Open
Keywords: oral cancer; oral and maxillofacial surgery; oral and maxillofacial pathology medicine; periodontics and oral pathology; immunohistochemistry
(This special issue belongs to the Section Pharmacology)
Therapeutic Potential of Natural Products in the Treatment of Nervous System Diseases
edited by Zhen Tian
submission deadline 31 Jan 2025 | Viewed by 86 | Submission Open
Keywords: natural products; nervous system diseases; drug discovery; neurodegeneration; neuroinflammation; chronic pain; neuropsychiatric disorders
(This special issue belongs to the Section Natural Products)
Recent Advances in Modulating Mitophagy with Novel Drugs/Compounds
edited by
submission deadline 5 Feb 2025 | Viewed by 67 | Submission Open
Keywords: heart disease; mitochondria; mitophagy; mitochondrial quality control; drug screening
(This special issue belongs to the Section Pharmacology)
New Street Opioids, Their Mixtures and Emerging Interventions
edited by Michael V. Voronkov
submission deadline 10 Feb 2025 | Viewed by 160 | Submission Open
Keywords: fentanyl; naloxone; xylazine; nitazenes; opioid overdose; addiction; polypharmacology; polypharmacy; animal models
(This special issue belongs to the Section Pharmacology)
Applications of Beehive Products for Wound Repair and Skin Care
edited by Simona Martinotti
submission deadline 15 Feb 2025 | Viewed by 113 | Submission Open
Keywords: anti-aging; antibacterial properties; healing properties; honey; propolis; bee venom; wound repair; skin care
(This special issue belongs to the Section Natural Products)
Targeted Therapies for Epilepsy
edited by , and Chiara Lucchi
submission deadline 20 Feb 2025 | 2 articles | Viewed by 2407 | Submission Open
Keywords: epilepsy; temporal lobe epilepsy; neurological disorder; spontaneous recurrent seizures; epileptogenesis; antiepileptogenic medications; antiseizure medications; drug-resistant epilepsy; adverse effects; drug discontinuation
(This special issue belongs to the Section Pharmacology)
Recent Advances in Inhalation Therapy
edited by and
submission deadline 20 Feb 2025 | 1 articles | Viewed by 1547 | Submission Open
Keywords: inhalation therapy; pulmonary delivery; aerosols; dry powder inhalation; inhalable micro and nanoparticles; pulmonary deposition
(This special issue belongs to the Section Pharmaceutical Technology)
New Pharmaceuticals in Diagnosis, Prognosis and Treatment of Myelofibrosis and Myeloproliferative Neoplasms
edited by and Calogero Vetro
submission deadline 20 Feb 2025 | Viewed by 101 | Submission Open
Keywords: philadelphia-negative Myeloproliferative neoplasms; JAK2; CALR; MPL; thrombotic risk; new targeted therapies; future landscape in MPN; inhibitors
(This special issue belongs to the Section Medicinal Chemistry)
Novel Therapeutics in Hematology
edited by
submission deadline 20 Feb 2025 | Viewed by 100 | Submission Open
Keywords: hematopoietic cell transplantation; cell therapy; acute myeloid leukemia; graft-versus-host disease; hematologic malignancies
(This special issue belongs to the Section Pharmacology)
Tumor Immunopharmacology submission deadline 21 Feb 2025 | Viewed by 324 | Submission Open
Keywords: immunotherapy; immunomodulation; drug development; cytokine receptor antagonist; T-cell based therapies; therapeutic antibodies; drug delivery; cancer vaccine
(This special issue belongs to the Section Pharmacology)
Indole Derivatives as Targeted Melatonin and Serotonin Receptor Ligands submission deadline 23 Feb 2025 | Viewed by 72 | Submission Open
Keywords: melatonin receptors; serotonin receptors; medicinal chemistry; natural products; drug design; antioxidant activity; multi-target compounds
(This special issue belongs to the Section Medicinal Chemistry)
Drug Discovery and Development Targeting NMDA Receptors
edited by
submission deadline 24 Feb 2025 | 1 articles | Viewed by 2637 | Submission Open
Keywords: glutamate; NMDAR antagonist; CNS drug discovery; Depression; neuropathic pain; Ketamine; memory and learning; ionotropic receptors
(This special issue belongs to the Section Medicinal Chemistry)
Development of Novel Radiopharmaceuticals for SPECT and PET Imaging
edited by
submission deadline 24 Feb 2025 | Viewed by 65 | Submission Open
Keywords: oncology; theranostics; inflammation/infection diagnosis; autoimmune diseases; neurodegenerative diseases; cardiovascular diseases
(This special issue belongs to the Section Radiopharmaceutical Sciences)
The Mode of Action of Herbal Medicines and Natural Products
edited by Hongnan Cao
submission deadline 25 Feb 2025 | 6 articles | Viewed by 8827 | Submission Open
(This special issue belongs to the Section Natural Products)
Natural Products and Their Modifications as Agents Used in the Fight against Pathogens
edited by
submission deadline 25 Feb 2025 | 6 articles | Viewed by 8631 | Submission Open
Keywords: plant extract; natural compounds; multidrug-resistant strains; intestinal microbiota; chemical modyfication; biotransformation
(This special issue belongs to the Section Natural Products)
Therapeutic Potential for Cannabinoid and Its Receptor submission deadline 25 Feb 2025 | 6 articles | Viewed by 8217 | Submission Open
Keywords: endocannabinoid system; cannabinoid receptor ligands; medical marihuana; cannabinoid-based therapies
(This special issue belongs to the Section Pharmacology)
Neuroprotective Potential of Natural Products: A Shield against Brain Decay submission deadline 25 Feb 2025 | 4 articles | Viewed by 7770 | Submission Open
Keywords: neuroprotection; natural products; extract; oxidative stress; degenerative diseases; adjuvant therapies
(This special issue belongs to the Section Natural Products)
Gut Microbiota Metabolites in Intestinal Inflammation and Fibrosis submission deadline 25 Feb 2025 | 4 articles | Viewed by 7043 | Submission Open
Keywords: intestinal inflammation; inflammatory bowel diseases; microbiota; microbiome; probiotics; fecal transplantation
(This special issue belongs to the Section Pharmacology)
Small Molecules in Targeted Cancer Therapy and Diagnosis
edited by
submission deadline 25 Feb 2025 | 4 articles | Viewed by 6130 | Submission Open
Keywords: small molecules; cancer therapy; cancer diagnosis; targeted therapy; theranostic agents
(This special issue belongs to the Section Pharmacology)
Pharmacological Therapies for Stress-Related Disorders and Autism Spectrum Disorder
edited by and
submission deadline 25 Feb 2025 | 3 articles | Viewed by 5981 | Submission Open
Keywords: new targets and therapies for stress-related disorders; molecular mechanism of drugs; ASD; PTSD; MDD; antidepressant; depression; animal model for depression; ASD; microbiome; gut-brain axis; brain electrophysiology; neuron activity in ASD
(This special issue belongs to the Section Pharmacology)
The Medical Applications of Novel PET Radiopharmaceuticals
edited by and Florent L. Besson
submission deadline 25 Feb 2025 | 4 articles | Viewed by 4414 | Submission Open
Keywords: nuclear medicine; radiotracers; radiopharmaceuticals; positron emission tomography; diagnostics; medical applications
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Psychiatric Drug Treatment and Drug Addiction submission deadline 25 Feb 2025 | 2 articles | Viewed by 2570 | Submission Open
Keywords: drug addiction; drug abuse; psychiatric disorder; drug dependence
(This special issue belongs to the Section Pharmacology)
Advances in Pediatric Drug Formulations submission deadline 25 Feb 2025 | 1 articles | Viewed by 1217 | Submission Open
Keywords: pediatric dosage forms; child-friendly dosage forms; age-appropriate dosage forms; acceptability; administration devices; taste-masking; compounded pediatric formulations
(This special issue belongs to the Section Pharmaceutical Technology)
Radiopharmaceuticals and Nanotechnology
edited by and Céline Mirjolet
submission deadline 25 Feb 2025 | 1 articles | Viewed by 1188 | Submission Open
Keywords: radiopharmaceutics; nanoparticle; radiation (external beam radiotherapy; nuclear medicine; brachytherapy; PET; SPECT; … ); theranostic; nanomedicine
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Small Molecule Drug Discovery: Driven by In-Silico Techniques
edited by
submission deadline 25 Feb 2025 | 1 articles | Viewed by 1174 | Submission Open
Keywords: drug discovery; nutraceuticals; virtual screening; docking; molecular dynamics; pharmacophore; lead compound
(This special issue belongs to the Section Medicinal Chemistry)
Advances in Nuclear Medicine submission deadline 25 Feb 2025 | Viewed by 209 | Submission Open
Keywords: radiopharmaceuticals; PET; SPECT; hybrid imaging modalities; radionuclide therapies; radiotracers; imaging techniques
Flavonoids in Medicinal Chemistry: Trends and Future Directions
edited by
submission deadline 25 Feb 2025 | Viewed by 194 | Submission Open
Keywords: flavonoids; synthesis; natural products; medicinal chemistry; biological activity
(This special issue belongs to the Section Medicinal Chemistry)
Neuropsychiatric Disorders: Pharmacological Aspects submission deadline 25 Feb 2025 | Viewed by 57 | Submission Open
Keywords: neuropsychiatric disorders; DSM-V; pharmacodynamics; innovative therapies; animal models; neuropsychiatric patients; trauma and stress; neurodegeneration; affective disorders; neurodevelopmental disorders; schizophrenia; sleep disorders; comorbidities; cardiovascular; coagulopathies; gastrointestinal; microbiome– gut– brain axis
(This special issue belongs to the Section Pharmacology)
Recent Advancements in Radiochemistry and PET Radiotracer Development: 2nd Edition
edited by Kenneth Dahl and
submission deadline 25 Feb 2025 | Viewed by 28 | Submission Open
Keywords: radiochemistry; labeling; automation; GMP; PET; radiotracer; radioligand; radiopharmaceutical; drug discovery
(This special issue belongs to the Section Radiopharmaceutical Sciences)
Pharmacotherapy for Macular Diseases 2024
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 830 | Submission Open
Keywords: clinical ophthalmology; macular degeneration; retinal diseases
(This special issue belongs to the Section Pharmacology)
Advancements in the Study of Biological Activities of Plant Extracts and Components submission deadline 28 Feb 2025 | Viewed by 125 | Submission Open
Keywords: natural products; enzyme kinetics; antioxidants; bioactive compounds; bioactive plant extracts
(This special issue belongs to the Section Natural Products)
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