Application of Polymeric Micelles for Drug and Gene Delivery, 2nd Edition
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 167
Special Issue Editors
Interests: self-assembly; amphiphilic polymers; solution properties; polymer and polymer-hybrid nanoparticles; drug/nucleic acid delivery systems; light scattering
Special Issues, Collections and Topics in MDPI journals
Interests: polymer micelles; polymer nanoparticles; nanocapsules; DNA/polymer complexes; hybrid nanoparticles; nanocarriers for the delivery of drugs and biomacromolecules
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Polymeric micelles have been extensively studied because of their ability to transfer biologically active agents, such as drugs and nucleic acids. They are formed as a result of the aggregation of amphiphilic block copolymers in aqueous solution. Thus, colloidal particles, mainly in a nanoscale composed of a hydrophobic core surrounded by a hydrophilic shell, are produced. Polymeric micelles are able to effectively solubilize hydrophobic drugs in their core, providing large encapsulation efficiency, high bioavailability, as well as controlled and targeted drug release. The micellar shell protects the hydrophobic part from biological invasion, but, similar to the core, it is also able to accommodate active substances of appropriate nature or genes and nucleic acids and serve as a carrier. Additionally, the specific micellar structure could be easily modified, allowing for the target design of polymeric delivery systems.
In this regard, the design and utilization of polymeric micelles to transport and deliver drugs and nucleic acids are active research areas undergoing continuing development. The aim of this Special Issue is to provide an overview of and summarize the current state of research of the application of polymeric micelles for drug and gene delivery.
This Special Issue is the second edition of the “Application of Polymeric Micelles for Drug and Gene Delivery”.
Prof. Dr. Stanislav Rangelov
Dr. Emi Haladjova
Guest Editors
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Keywords
- polymeric micelles
- micelleplexes
- drug delivery
- gene delivery
- drug release
- nanomedicine
- gene therapy
- theranostics
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