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Polymeric Nanofibers and Nanoparticles for Nanomedicine Applications

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 3366

Special Issue Editor


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Guest Editor
Department of Chemical and Biomolecular Engineering, University of Nebraska-Lincoln, Lincoln, NE, USA
Interests: nanomedicine; tissue engineering; drug delivery; wound healing; hemostatic patches; controlled release; nanoparticle; nanofiber; targeted drug release; electrospray; electrospinning; emulsion polymerization; self-assembly; nanostructure; liposomes; catalysis

Special Issue Information

Dear Colleagues,

We have come a long way since Norio Taniguchi’s coining of the word “nanotechnology” for the first time in 1974. Our ability to control and characterize structures with submicron characteristic lengths has improved steadily since then. While commercial applications of nanotechnology in electronics, energy and IT took an early lead, the long and patient path taken by scientists, engineers and business leaders to fund and develop nano-inspired medical products has started to produce concrete results. Commercial applications rely on gold nanoparticles for the detection of specific sequences of nucleic acids. Abraxane, an albumin-bound paclitaxel, has been approved by the FDA for the treatment of a variety of cancers, as have Rapamune nanocrystals and liposome-encapsulated forms of Doxil and irinotecan. These are just a few examples of the current $150B/year nanomedicine market, according to a July 2020 Industry Research report.

This Special Issue of Polymers is dedicated to the dissemination of new and exciting nanomedicine research. Basic materials research that aims at the development of nano-inspired medical applications, in vitro and in vivo testing of nanomaterials, nanoparticle toxicity, and the development of theoretical and empirical models used to understand structure–function relationships are just examples of the types of original contributions being sought. The submission of subdiscipline-specific reviews is also welcome.

Prof. Dr. Gustavo Larsen
Guest Editor

Manuscript Submission Information

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Keywords

  • Nanomedicine
  • Nanoparticle
  • Nanofiber
  • Liposome
  • Drug delivery
  • Controlled release
  • Wound healing
  • Self-assembly
  • Electrospray
  • Electrospinning
  • Tissue engineering
  • Hemostatic patches
  • Targeted drug delivery
  • Emulsion polymerization
  • Nanostructure
  • Theranostics
  • Nanoparticle imaging
  • Bactericide nanostructures

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Published Papers (1 paper)

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Research

14 pages, 4314 KiB  
Article
An N-Halamine/Graphene Oxide-Functionalized Electrospun Polymer Membrane That Inactivates Bacteria on Contact and by Releasing Active Chlorine
by Shi Lan, Jinghua Zhang, Jie Li, Yanan Guo, Xianliang Sheng and Alideertu Dong
Polymers 2021, 13(16), 2784; https://doi.org/10.3390/polym13162784 - 19 Aug 2021
Cited by 8 | Viewed by 2231
Abstract
The emergence of antibiotic-resistant “superbugs” in recent decades has led to widespread illness and death and is a major ongoing public health issue. Since traditional antimicrobials and antibiotics are in many cases showing limited or no effectiveness in fighting some emerging pathogens, there [...] Read more.
The emergence of antibiotic-resistant “superbugs” in recent decades has led to widespread illness and death and is a major ongoing public health issue. Since traditional antimicrobials and antibiotics are in many cases showing limited or no effectiveness in fighting some emerging pathogens, there is an urgent need to develop and explore novel antibacterial agents that are both powerful and reliable. Combining two or more antibiotics or antimicrobials has become a hot topic in antibacterial research. In this contribution, we report on using a simple electrospinning technique to create an N-halamine/graphene oxide-modified polymer membrane with excellent antibacterial activity. With the assistance of advanced techniques, the as-obtained membrane was characterized in terms of its chemical composition, morphology, size, and the presence of active chlorine. Its antibacterial properties were tested with Escherichia coli (E. coli) as the model bacteria, using the colony-counting method. Interestingly, the final N-halamine/graphene oxide-based antibacterial fibrous membrane inactivated E. coli both on contact and by releasing active chlorine. We believe that the synergistic antimicrobial action of our as-fabricated fibrous membrane should have great potential for utilization in water disinfection, air purification, medical and healthcare products, textile products, and other antibacterial-associated fields. Full article
(This article belongs to the Special Issue Polymeric Nanofibers and Nanoparticles for Nanomedicine Applications)
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