Vaccination into the Dermal Compartment: Techniques, Challenges, and Prospects
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Vaccination Optimization".
Deadline for manuscript submissions: 31 December 2024 | Viewed by 1
Special Issue Editors
Interests: veterinary medicine; virology (including SARS-CoV-2); immunology
Special Issues, Collections and Topics in MDPI journals
Interests: vaccines; nucleic acid-based and virally vectored technologies; virology; immunology; gene therapy; vaccine delivery; genetic engineering; clinical trials; regulatory compliance
Special Issue Information
Dear Colleagues,
Vaccination into the dermal compartment is an attractive delivery route due to the rich populations of immune cells in this tissue space. Due to this, it is possible to use less vaccine and induce an effective immune response that is similar or even enhanced compared to intramuscular delivery using larger doses. This dose-sparing is especially desired in situations where there is limited vaccine availability or resources to obtain needed doses, such as during the COVID-19 pandemic and global monkeypox outbreaks, or to decrease per-person cost for more expensive vaccines in developing countries. Other benefits can include increased acceptability by patients and caregivers compared to intramuscular injection. Despite the benefits of intradermal vaccination, challenges remain, such as limited numbers of healthcare workers trained in intradermal injection with needle/syringe and low availability of cost-effective measures to vaccinate large populations.
This Special Issue aims to address the various benefits and challenges that scientists, public health groups, and government officials encounter when employing intradermal vaccine delivery in order to inform the development of vaccination regimens and health and policy decisions to implement vaccination campaigns.
In this Special Issue, original research articles, reviews, opinion articles, and case reports are welcome. Research areas may include (but are not limited to):
- Intradermal vaccination regimens, injection techniques, physical delivery methods (needle and syringe, electroporation, jet injection, microneedles, etc.), comparison to other routes of injection
- Development of new intradermal vaccination technologies
- Public health and policy issues, including mass vaccination campaign planning and deployment, and costs analyses of different intradermal vaccination techniques
We look forward to receiving your contributions.
Dr. Carmen Ledesma-Feliciano
Dr. Erin Spiegel
Guest Editors
Manuscript Submission Information
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Keywords
- vaccines
- intradermal
- vaccine delivery
- vaccination campaign
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