Diseases of the Gastrointestinal Tract, Liver and Pancreas in Dogs and Cats

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Internal Medicine".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 2426

Special Issue Editors


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Guest Editor
Companion Animal Clinic, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece
Interests: small-animal gastrointestinal and pancreatic diseases; small-animal flexible endoscopy; small-animal respiratory, kidney and urinary diseases
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Guest Editor
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
Interests: gastroenterology; GI endoscopy; performance of clinical trials; inflammatory bowel disease in dogs and cats; the investigation of host-microbiota interactions mediating GI health and disease
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Companion Animal Clinic (Medicine Unit), School of Veterinary Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece
Interests: liver diseases; gastrointestinal diseases; biliary tract diseases; pancreatic diseases; inflammatory bowel disease; canine; digestive system endoscopy; gastroenterology; veterinary internal medicine; gastrointestinal endoscopy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Gastroenterology and hepatology are dynamic fields of research and clinical practice in small-animal internal medicine. Significant progress has been made in our understanding of liver, biliary, pancreatic and gastrointestinal diseases over the last two decades. The standard of care has evolved; some new diagnostic tools have been developed, and treatment recommendations have been updated.

The goal of this Special Issue is to provide readers with updates on the etiology, diagnosis, management and treatment of some of the most common gastrointestinal, hepatic and pancreatic diseases and disorders clinicians come across on a daily basis. A further aim of this Special Issue is to highlight developing research areas related to alimentary tract diseases of dogs and cats.

In this Special Issue, original research articles and reviews are welcome. Research areas may include, but are not limited to, the following: chronic and acute enteropathies, infectious disease, chronic hepatitis, pancreatitis, GI disease biomarkers and advances in laboratory diagnostic tests, imaging, histopathology and nutrition in digestive diseases. Papers in the form of case reports are also welcome.

Prof. Dr. Katerina K. Adamama-Moraitou
Prof. Dr. Albert E. Jergens
Dr. Alexandros O. Konstantinidis
Guest Editors

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Keywords

  • gastrointestinal diseases
  • hepatobiliary diseases
  • pancreatic diseases
  • inflammatory enteropathies biomarkers
  • microbiome
  • probiotics
  • histopathology
  • diagnostic tests
  • imaging

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Published Papers (2 papers)

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Research

10 pages, 2873 KiB  
Article
Computed Tomographic Hepatic Volumetry in Dogs with Congenital Portosystemic Shunts
by Hitomi Kurihara, George Moore and Masahiro Murakami
Vet. Sci. 2024, 11(9), 390; https://doi.org/10.3390/vetsci11090390 - 24 Aug 2024
Viewed by 821
Abstract
CTHV is a non-invasive and accurate method for assessing liver volume in dogs. CTHV has not been studied in each type of extrahepatic PSS in dogs. This study aimed to use CTHV to compare liver volumes in dogs with different types of PSSs [...] Read more.
CTHV is a non-invasive and accurate method for assessing liver volume in dogs. CTHV has not been studied in each type of extrahepatic PSS in dogs. This study aimed to use CTHV to compare liver volumes in dogs with different types of PSSs that had been confirmed by computed tomography angiography. Dogs with PSSs were retrospectively included and categorized into IH, EHPC, EHPA, or EHPP shunt groups. Manual CTHV was performed, and the normalized liver volume (nLV) and the difference in nLV from the estimated liver volume calculated based on body weight (LV%diff) was calculated. The study included 57 dogs: 20 IH, 21 EHPC, 9 EHPA, and 7 EHPP. The median nLV (cm3/kg) and LV%diff (%) for each group were as follows: IH 17.3 (−40.4%); EHPC 16.9 (−60.3%); EHPA 15.1 (−56.7%); and EHPP 17.2 (−59.2%), respectively. There were no significant differences in nLV among the PSS types. However, LV%diff was significantly more pronounced in the EHPC and EHPA groups compared with the IH group. Additionally, smaller dogs exhibited more severe microhepatia, with a significant positive correlation between LV%diff and body weight (p < 0.01). These findings suggest that microhepatia severity varies by shunt type and is more severe in smaller dogs, highlighting the need for further research to understand the underlying mechanisms. Full article
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18 pages, 2191 KiB  
Article
Microbiota in Mild Inflammatory Bowel Disease (IBD) Can Be Modulated by Beta-Glucans and Mannanoligosaccharides: A Randomized, Double-Blinded Study in Dogs
by Andressa Rodrigues Amaral, Mariana Fragoso Rentas, Thais Caroline Taveira Rosa, Thais Araújo Esteves Pereira, Pedro Henrique Marchi, Fabio Alves Teixeira, Fernando de Oliveira Roberti Filho, Thaila Cristina Putarov, Bruno Cogliati, Thiago Henrique Annibale Vendramini, Júlio Cesar de Carvalho Balieiro and Marcio Antonio Brunetto
Vet. Sci. 2024, 11(8), 349; https://doi.org/10.3390/vetsci11080349 - 1 Aug 2024
Viewed by 1246
Abstract
Inflammatory bowel disease (IBD) in dogs is the most common chronic gastrointestinal disease in dogs. Its etiology evolves an aberrant immunological response towards food antigens and indigenous bacteria in the gut bacteria and, consequently, dysbiosis. Prebiotics provide substrates for the growth of beneficial [...] Read more.
Inflammatory bowel disease (IBD) in dogs is the most common chronic gastrointestinal disease in dogs. Its etiology evolves an aberrant immunological response towards food antigens and indigenous bacteria in the gut bacteria and, consequently, dysbiosis. Prebiotics provide substrates for the growth of beneficial bacteria and promote the production of beneficial fermentation products. This study aimed to evaluate the effects of oral supplementations of beta-glucans and mannanoligosaccharides (MOSs) over 60 days in fecal microbiota and fecal concentrations of fermentation products in dogs with mild IBD. Eighteen dogs with mild IBD were divided into three experimental groups in a blinded and randomized manner: A—dogs received 0.1% of a beta-glucan-based prebiotic, B—dogs received 0.1% of a MOS + beta-glucan-based prebiotic, and C—dogs received 0.1% of a placebo. Fecal microbiota was analyzed using the latest generation 16S rRNA sequencing (Illumina®). Relative abundances of each taxon were analyzed using a generalized linear model, and fermentation products using a mixed model. A significance level of p was used. The prebiotics positively modulated the bacterial population of Firmicutes and Bacteroidetes. Treatment A improved alpha diversity and populations of beneficial bacteria. Beta-glucan supplementation for 60 days had beneficial effects on modulating intestinal microbiota in dogs with mild IBD. Full article
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