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67 Results Found

  • Article
  • Open Access
2 Citations
1,608 Views
12 Pages

Pre-Operative Mechanical Bowel Preparation Does Not Affect the Impact of Anastomosis Leakage in Left-Side Colorectal Surgery—A Single Center Observational Study

  • Ludovít Danihel,
  • Marian Cerny,
  • Ivor Dropco,
  • Petra Zrnikova,
  • Milan Schnorrer,
  • Marek Smolar,
  • Miloslav Misanik and
  • Stefan Durdik

30 August 2024

Despite rapid advances in colorectal surgery, morbidity and mortality rates in elective gastrointestinal surgery play a significant role. For decades, there have been tempestuous discussions on preventative measures to minimize the risk of anastomoti...

  • Article
  • Open Access
4 Citations
2,485 Views
6 Pages

26 September 2022

Aim: Surgical resection remains the treatment of choice for curable esophageal cancer patients. Anastomotic leakage after esophagectomy with an intrathoracic anastomosis is the most feared complication, and is the main cause of postoperative morbidit...

  • Article
  • Open Access
1 Citations
2,114 Views
12 Pages

Cyanoacrylate in Colorectal Surgery: Is It Safe?

  • Anna D’Amore,
  • Pietro Anoldo,
  • Michele Manigrasso,
  • Giovanni Aprea,
  • Giovanni Domenico De Palma and
  • Marco Milone

7 August 2023

Anastomotic leakage (AL) of a gastrointestinal (GI) anastomosis continues to be an important complication in GI surgery. Since its introduction more than 60 years ago, Cyanoacrylate (CA) has gained popularity in colorectal surgery to provide “p...

  • Article
  • Open Access
1 Citations
4,233 Views
14 Pages

Ileocolic Anastomosis Dehiscence in Colorectal Cancer Surgery

  • Sara Lima Gomes,
  • Pedro Miguel Dias dos Santos,
  • Joaquim Costa Pereira and
  • Sandra F. Martins

Background: Anastomotic leakage (AL) is one of the most feared complications in colorectal cancer (CRC) surgery. Although many series have reported the general risk factors for AL, published studies focusing on ileocolic anastomosis are scarce. The m...

  • Article
  • Open Access
2,081 Views
8 Pages

Our previous retrospective observational study demonstrated the safety of laparoscopically assisted subtotal colectomy with ileorectal anastomosis and preservation of the superior rectal artery (SRA), without instances of leakage, in patients with sl...

  • Article
  • Open Access
6 Citations
2,311 Views
10 Pages

A 25 mm Circular Stapler Anastomosis Is Associated with Higher Anastomotic Leakage Rates Following Minimally Invasive Ivor Lewis Operation

  • Tobias Hofmann,
  • Matthias Biebl,
  • Sebastian Knitter,
  • Uli Fehrenbach,
  • Sascha Chopra,
  • Candan Cetinkaya-Hosgor,
  • Jonas Raakow,
  • Philippa Seika,
  • Rupert Langer and
  • Johann Pratschke
  • + 2 authors

2 December 2022

(1) Background: Minimally invasive oesophagectomy (MIE) with intrathoracic anastomosis is increasingly used in treating patients with oesophageal cancer. Anastomotic leakage (AL) remains a critical perioperative complication, despite recent advances...

  • Article
  • Open Access
4 Citations
2,313 Views
9 Pages

Anastomotic Rings and Inflammation Values as Biomarkers for Leakage of Stapled Circular Colorectal Anastomoses

  • Feng Zhang,
  • Song Qiao,
  • Ning Yao,
  • Chunqiao Li,
  • Marie-Christin Weber,
  • Benedict Jefferies,
  • Helmut Friess,
  • Stefan Reischl and
  • Philipp-Alexander Neumann

22 November 2022

Reliable markers to predict or diagnose anastomotic leakage (AL) of stapled circular anastomoses following colorectal resections are an important clinical need. Here, we aim to quantitatively investigate the morphology of anastomotic rings as an earl...

  • Article
  • Open Access
1,246 Views
21 Pages

Anastomotic leaks after colorectal resection are serious surgical complications. We have compared the integrity of two common colorectal anastomosis techniques, end-to-side (ES) and end-to-end (EE), to control specimens using a novel experimental set...

  • Article
  • Open Access
10 Citations
3,706 Views
18 Pages

Reinforcement of Colonic Anastomosis with Improved Ultrafine Nanofibrous Patch: Experiment on Pig

  • Jachym Rosendorf,
  • Marketa Klicova,
  • Lenka Cervenkova,
  • Jana Horakova,
  • Andrea Klapstova,
  • Petr Hosek,
  • Richard Palek,
  • Jan Sevcik,
  • Robert Polak and
  • Vladislav Treska
  • + 2 authors

Anastomotic leakage is a dreadful complication in colorectal surgery. It has a negative impact on postoperative mortality, long term life quality and oncological results. Nanofibrous polycaprolactone materials have shown pro-healing properties in var...

  • Systematic Review
  • Open Access
16 Citations
3,486 Views
13 Pages

Predictive Factors for Anastomotic Leakage after Laparoscopic and Open Total Gastrectomy: A Systematic Review

  • Umberto Bracale,
  • Roberto Peltrini,
  • Marcello De Luca,
  • Mariangela Ilardi,
  • Maria Michela Di Nuzzo,
  • Alberto Sartori,
  • Maurizio Sodo,
  • Michele Danzi,
  • Francesco Corcione and
  • Carlo De Werra

26 August 2022

The aim of this systematic review is to identify patient-related, perioperative and technical risk factors for esophago-jejunal anastomotic leakage (EJAL) in patients undergoing total gastrectomy for gastric cancer (GC). A comprehensive literature se...

  • Article
  • Open Access
2 Citations
1,505 Views
11 Pages

Non-Thermal Atmospheric Pressure Plasma as an Adjunct to Intestinal Anastomosis: A Pilot Study on Preventing Anastomotic Leaks

  • Mario Betancourt-Ángeles,
  • Régulo López-Callejas,
  • Guillermo Berrones-Stringel,
  • César Jaramillo-Martínez,
  • Bryan Navarro-Luna,
  • Benjamín Gonzalo Rodríguez-Méndez,
  • Antonio Mercado-Cabrera and
  • Raúl Valencia-Alvarado

8 November 2024

Anastomotic leaks remain a significant challenge in intestinal surgery, often leading to severe complications. This study investigated a novel approach to enhance anastomotic healing and reduce the risk of leaks by combining traditional suturing and...

  • Article
  • Open Access
5 Citations
2,830 Views
15 Pages

Anastomotic Leakage after Colorectal Surgery in Ovarian Cancer: Drainage, Stoma Utility and Risk Factors

  • Liliana Mereu,
  • Francesca Dalprà,
  • Valeria Berlanda,
  • Riccardo Pertile,
  • Daniela Coser,
  • Basilio Pecorino,
  • Maria Gabriella D’Agate,
  • Francesco Ciarleglio,
  • Alberto Brolese and
  • Saverio Tateo

18 December 2022

Objective: to evaluate the incidence of anastomotic leakage (AL), risk factors and utility of drainage and stoma in patients undergoing intestinal surgery for ovarian cancer in a single institution and in a review of the literature. Methods: retrospe...

  • Article
  • Open Access
1,498 Views
11 Pages

A Novel Deep Learning Model for Predicting Colorectal Anastomotic Leakage: A Pioneer Multicenter Transatlantic Study

  • Miguel Mascarenhas,
  • Francisco Mendes,
  • Filipa Fonseca,
  • Eduardo Carvalho,
  • Andre Santos,
  • Daniela Cavadas,
  • Guilherme Barbosa,
  • Antonio Pinto da Costa,
  • Miguel Martins and
  • Abdullah Bunaiyan
  • + 8 authors

3 August 2025

Background/Objectives: Colorectal anastomotic leak (CAL) is one of the most severe postoperative complications in colorectal surgery, impacting patient morbidity and mortality. Current risk assessment methods rely on clinical and intraoperative facto...

  • Brief Report
  • Open Access
2 Citations
3,771 Views
4 Pages

2 April 2022

Anastomotic leakage remains the most feared complication in colorectal surgery. Various intraoperative tests evaluate bowel perfusion and mechanical integrity of the colorectal anastomosis. These tests reduce the risk of postoperative anastomotic lea...

  • Article
  • Open Access
2 Citations
4,677 Views
13 Pages

23 August 2021

Extended colon resection is often performed in advanced ovarian cancer. Restoring intestinal continuity and avoiding stoma creation improve patients’ quality of life postoperatively. We tried to minimize the number of anastomoses, restore intestinal...

  • Article
  • Open Access
3 Citations
3,089 Views
9 Pages

Supermicrosurgical Suture-Stent Technique for A Lymphaticovenular Bypass

  • Ryo Karakawa,
  • Hidehiko Yoshimatsu,
  • Keisuke Kamiya,
  • Yuma Fuse and
  • Tomoyuki Yano

11 June 2021

Background: Lymphaticovenular anastomosis (LVA) is a challenging procedure and requires a sophisticated supermicrosurgical technique. The aim of this study was to evaluate and establish a discrete supermicrosurgical anastomosis method using the “sutu...

  • Review
  • Open Access
35 Citations
26,418 Views
17 Pages

Review of Colonic Anastomotic Leakage and Prevention Methods

  • Alex H. Fang,
  • Wilson Chao and
  • Melanie Ecker

16 December 2020

Although surgeries involving anastomosis are relatively common, anastomotic leakages are potentially deadly complications of colorectal surgeries due to increased risk of morbidity and mortality. As a result of the potentially fatal effects of anasto...

  • Article
  • Open Access
5 Citations
2,772 Views
11 Pages

Intraoperative Control of Hemoglobin Oxygen Saturation in the Intestinal Wall during Anastomosis Surgery

  • Daniil M. Kustov,
  • Tatiana A. Savelieva,
  • Timofey A. Mironov,
  • Sergey S. Kharnas,
  • Vladimir V. Levkin,
  • Andrey S. Gorbunov,
  • Artem A. Shiryaev and
  • Victor B. Loschenov

4 October 2021

During surgery for colon cancer, monitoring of the oxygen saturation of hemoglobin in the tissues under study makes it possible to assess the degree of blood supply to the anastomosis areas of the colon. Adequate blood supply in this area is decisive...

  • Article
  • Open Access
1,983 Views
13 Pages

18 March 2024

The hemidouble stapler technique (HDST) in laparoscopic intracorporeal esophagojejunostomy has aspects that pose risks to the safety of the anastomosis. We developed a new esophagojejunostomy technique that converts a double-stapled anastomosis to a...

  • Article
  • Open Access
7 Citations
2,206 Views
13 Pages

Ureterovesical Anastomosis Complications in Kidney Transplantation: Definition, Risk Factor Analysis, and Prediction by Quantitative Fluorescence Angiography with Indocyanine Green

  • Andreas L. H. Gerken,
  • Kai Nowak,
  • Alexander Meyer,
  • Maximilian C. Kriegmair,
  • Christel Weiss,
  • Bernhard K. Krämer,
  • Pauline Glossner,
  • Katharina Heller,
  • Ioannis Karampinis and
  • Frank Kunath
  • + 5 authors

7 November 2022

Ureteral stenosis and urinary leakage are relevant problems after kidney transplantation. A standardized definition of ureterovesical anastomosis complications after kidney transplantation has not yet been established. This study was designed to demo...

  • Article
  • Open Access
4 Citations
3,005 Views
12 Pages

The use of intraoperative colonoscopy (IOC) to evaluate the integrity of newly created anastomosis has been advocated by some surgeons. However, whether direct visualization of fresh anastomosis can help reduce anastomotic problems is still unclear....

  • Article
  • Open Access
21 Citations
12,222 Views
18 Pages

26 August 2022

Background: A total esophagectomy with gastric tube reconstruction is the mainstream procedure for esophageal cancer. Colon interposition and free jejunal flap for esophageal reconstruction are the alternative choices when the gastric tube is not ava...

  • Article
  • Open Access
1,225 Views
19 Pages

A Novel and Feasible Intracorporeal Esophagojejunostomy Anastomosis in Totally Laparoscopic Total Gastrectomy Surgery: Sutureless L-Shape with Endoscopic Assistance (SLEJ)

  • Ibrahim Burak Bahcecioglu,
  • Sumeyra Guler,
  • Sevket Baris Morkavuk,
  • Mujdat Turan,
  • Gokhan Giray Akgul,
  • Mirac Baris Erzincan,
  • Kubilay Kenan Ozluk,
  • Osman Bardakci and
  • Mehmet Ali Gulcelik

25 April 2025

Background and Objectives: In contrast to the standardization of laparoscopic gastrectomy techniques, the complexity of intracorporeal anastomosis techniques in totally laparoscopic total gastrectomy, the lack of standardization, the positional chall...

  • Article
  • Open Access
1 Citations
1,328 Views
18 Pages

Local Application of Minimally Manipulated Autologous Stromal Vascular Fraction (SVF) Reduces Inflammation and Improves Bilio-Biliary Anastomosis Integrity

  • Ilya Klabukov,
  • Garnik Shatveryan,
  • Nikolay Bagmet,
  • Olga Aleshina,
  • Elena Ivanova,
  • Victoria Savina,
  • Ilmira Gilmutdinova,
  • Dmitry Atiakshin,
  • Michael Ignatyuk and
  • Denis Baranovskii
  • + 4 authors

30 December 2024

Bilio-biliary anastomosis (BBA) is a critical surgical procedure that is performed with the objective of restoring bile duct continuity. This procedure is often required in cases where there has been an injury to the extrahepatic bile ducts or during...

  • Article
  • Open Access
2 Citations
2,179 Views
13 Pages

Evaluation of the Effect of an Intraperitoneal Cytostatic-Loaded Supramolecular Hydrogel on Intestinal Anastomotic Healing in an Animal Model

  • Danique J. I. Heuvelings,
  • Anne G. W. E. Wintjens,
  • Audrey C. H. M. Jongen,
  • Maurits J. C. A. M. Gielen,
  • Kaatje Lenaerts,
  • Peter-Paul K. H. Fransen,
  • Marion J. Gijbels,
  • Geert C. van Almen,
  • Patricia Y. W. Dankers and
  • Ignace H. J. T. de Hingh
  • + 1 author

18 October 2023

The prognosis of colorectal cancer patients with peritoneal metastases is very poor. Intraperitoneal drug delivery systems, like supramolecular hydrogels, are being developed to improve local delivery and intraperitoneal residence time of a cytostati...

  • Feature Paper
  • Article
  • Open Access
8 Citations
5,337 Views
15 Pages

Post-Operative Monitoring of Intestinal Tissue Oxygenation Using an Implantable Microfabricated Oxygen Sensor

  • Jamie R. K. Marland,
  • Mark E. Gray,
  • David J. Argyle,
  • Ian Underwood,
  • Alan F. Murray and
  • Mark A. Potter

10 July 2021

Anastomotic leakage (AL) is a common and dangerous post-operative complication following intestinal resection, causing substantial morbidity and mortality. Ischaemia in the tissue surrounding the anastomosis is a major risk-factor for AL development....

  • Technical Note
  • Open Access
10 Citations
3,144 Views
8 Pages

Laparoscopic Laser Speckle Contrast Imaging Can Visualize Anastomotic Perfusion: A Demonstration in a Porcine Model

  • Aurelia Wildeboer,
  • Wido Heeman,
  • Arne van der Bilt,
  • Christiaan Hoff,
  • Joost Calon,
  • E. Christiaan Boerma,
  • Mahdi Al-Taher and
  • Nicole Bouvy

16 August 2022

Background: Intestinal resection causes inevitable vascular damage, which cannot always be seen during an intraoperative clinical assessment of local intestinal perfusion. If left unaltered, impaired perfusion can lead to complications, such as anast...

  • Article
  • Open Access
2 Citations
2,226 Views
8 Pages

The Efficacy of Urinary Continence in Patients Undergoing Robot-Assisted Radical Prostatectomy with Bladder-Prostatic Muscle Reconstruction and Bladder Neck Eversion Anastomosis

  • Yang Luan,
  • Xue-Fei Ding,
  • Sheng-Ming Lu,
  • Tian-Bao Huang,
  • Ji Chen,
  • Qin Xiao,
  • Li-Ping Wang,
  • Hao-Peng Chen and
  • Yue-Xing Han

10 December 2022

Background and Objectives: To evaluate the efficacy of bladder-prostatic muscle reconstruction and bladder neck eversion anastomosis in the recovery of urinary continence after robot-assisted radical prostatectomy (RARP). Materials and Methods: From...

  • Article
  • Open Access
16 Citations
4,229 Views
8 Pages

Intracorporeal versus Extracorporeal Anastomosis for Laparoscopic Right Hemicolectomy: Short-Term Outcomes

  • Antonio Biondi,
  • Gianluca Di Mauro,
  • Riccardo Morici,
  • Giuseppe Sangiorgio,
  • Marco Vacante and
  • Francesco Basile

19 December 2021

Laparoscopic right hemicolectomy represents an effective therapeutic approach for right colon cancer (RCC). The primary aim of this study was to evaluate bowel function recovery, length of hospital stay, operative time, and the number of general and...

  • Article
  • Open Access
2,270 Views
17 Pages

The Combined Effect of Western Diet Consumption and Diclofenac Administration Alters the Gut Microbiota and Promotes Anastomotic Leakage in the Distal Colon

  • Melissa N. N. Arron,
  • Stijn Bluiminck,
  • Richard P. G. ten Broek,
  • Thomas H. A. Ederveen,
  • Lindsay Alpert,
  • Olga Zaborina,
  • John C. Alverdy and
  • Harry van Goor

24 September 2024

Background: Obesity, Western diet (WD) consumption, and the use of non-steroidal anti-inflammatory drugs (NSAIDs) are co-occurring and modifiable factors associated with microbiome dysbiosis and anastomotic leakage. We studied the combined effect of...

  • Article
  • Open Access
7 Citations
3,356 Views
14 Pages

The occurrence of leakage from anastomotic sites is a significant issue given its potential undesirable complications. The management of anastomotic leakage after gastrointestinal surgery is particularly crucial because it is directly associated with...

  • Article
  • Open Access
22 Citations
4,779 Views
16 Pages

Imaging PPG for In Vivo Human Tissue Perfusion Assessment during Surgery

  • Marco Lai,
  • Stefan D. van der Stel,
  • Harald C. Groen,
  • Mark van Gastel,
  • Koert F. D. Kuhlmann,
  • Theo J. M. Ruers and
  • Benno H. W. Hendriks

Surgical excision is the golden standard for treatment of intestinal tumors. In this surgical procedure, inadequate perfusion of the anastomosis can lead to postoperative complications, such as anastomotic leakages. Imaging photoplethysmography (iPPG...

  • Article
  • Open Access
7 Citations
1,822 Views
9 Pages

Quadruple Assessment of Colorectal Anastomosis after Laparoscopic Rectal Resection: A Retrospective Analysis of a Propensity-Matched Cohort

  • Filippo Carannante,
  • Guglielmo Niccolò Piozzi,
  • Valentina Miacci,
  • Gianfranco Bianco,
  • Gennaro Melone,
  • Vincenzo Schiavone,
  • Gianluca Costa,
  • Marco Caricato,
  • Jim S. Khan and
  • Gabriella Teresa Capolupo

27 August 2024

Background: Anastomotic leakage (AL) is one of the most feared complications in colorectal surgery, with an incidence of 12–39% and associated risk of mortality of 2–24%. The causes of AL and the ways to prevent it are currently under inv...

  • Article
  • Open Access
1,036 Views
11 Pages

Local Myoelectric Sensing During Human Colonic Tissue Perfusion

  • Matan Ben-David,
  • Raj Makwana,
  • Tal Yered,
  • Gareth J. Sanger,
  • Charles H. Knowles,
  • Nir Wasserberg and
  • Erez Shor

20 December 2024

Objectives: Anastomotic leakage (AL) is one of the most devastating complications after colorectal surgery. The verification of the adequate perfusion of the anastomosis is essential to ensuring anastomosis integrity following colonic resections. Thi...

  • Article
  • Open Access
8 Citations
3,989 Views
11 Pages

Recognition of Postoperative Cystography Features by Artificial Intelligence to Predict Recovery from Postprostatectomy Urinary Incontinence: A Rapid and Easy Way to Predict Functional Outcome

  • I-Hung Shao,
  • Hung-Cheng Kan,
  • Hung-Yi Chen,
  • Ying-Hsu Chang,
  • Liang-Kang Huang,
  • Yuan-Cheng Chu,
  • Po-Hung Lin,
  • Kai-Jie Yu,
  • Cheng-Keng Chuang and
  • See-Tong Pang
  • + 1 author

8 January 2023

Purpose: Post-operative cystography has been used to predict the recovery of postprostatectomy urinary incontinence (PPI) in patients with localized prostate cancer. This study aimed to validate the predictive value of cystography for PPI and utilize...

  • Review
  • Open Access
21 Citations
4,215 Views
12 Pages

Current Insights: The Impact of Gut Microbiota on Postoperative Complications in Visceral Surgery—A Narrative Review

  • Ann-Kathrin Lederer,
  • Sophia Chikhladze,
  • Eva Kohnert,
  • Roman Huber and
  • Alexander Müller

13 November 2021

Postoperative complications are a major problem occurring in up to 50% of patients undergoing major abdominal surgery. Occurrence of postoperative complications is associated with a significantly higher morbidity and mortality in affected patients. T...

  • Article
  • Open Access
4 Citations
3,765 Views
10 Pages

Could Stoma Be Avoided after Laparoscopic Low Anterior Resection for Rectal Cancer? Experience with Transanal Tube in 195 Cases

  • Antonio Sciuto,
  • Roberto Peltrini,
  • Federica Andreoli,
  • Andrea Gianmario Di Santo Albini,
  • Maria Michela Di Nuzzo,
  • Nello Pirozzi,
  • Marcello Filotico,
  • Federica Lauria,
  • Giuseppe Boccia and
  • Michele D’Ambra
  • + 4 authors

Anastomotic leakage is the most-feared complication of rectal surgery. Transanal devices have been suggested for anastomotic protection as an alternative to defunctioning stoma, although evidence is conflicting, and no single device is widely used in...

  • Review
  • Open Access
8 Citations
2,965 Views
16 Pages

What Is the Role of the Gut Microbiota in Anastomotic Leakage After Colorectal Resection? A Scoping Review of Clinical and Experimental Studies

  • Georgios D. Lianos,
  • Maximos Frountzas,
  • Ilektra D. Kyrochristou,
  • Panagiotis Sakarellos,
  • Vasileios Tatsis,
  • Gerasimia D. Kyrochristou,
  • Christina D. Bali,
  • Maria Gazouli,
  • Michail Mitsis and
  • Dimitrios Schizas

5 November 2024

Background: Anastomotic leakage (AL) still remains a common complication after colorectal anastomosis that leads to increased morbidity and mortality. The gut microbiota has been hypothesized as one of the risk factors associated with anastomotic lea...

  • Article
  • Open Access
7 Citations
2,731 Views
10 Pages

Comparison of Two Endoscopic Therapeutic Interventions as Primary Treatment for Anastomotic Leakages after Total Gastrectomy

  • Moritz Senne,
  • Christoph R. Werner,
  • Ulrike Schempf,
  • Karolin Thiel,
  • Alfred Königsrainer and
  • Dörte Wichmann

16 June 2022

Introduction: An esophagojejunal anastomotic leak following an oncological gastrectomy is a life-threatening complication, and its management is challenging. A stent application and endoscopic negative pressure therapy are possible therapeutic option...

  • Article
  • Open Access
7 Citations
2,167 Views
10 Pages

18 November 2021

Background: We evaluated the feasibility and safety of stentless uretero-intestinal anastomosis (UIA) during radical cystectomy (RC) with an ileal orthotopic neobladder. Methods: We retrospectively reviewed 403 patients who underwent RC for bladder c...

  • Article
  • Open Access
2 Citations
1,576 Views
13 Pages

The Value of C-Reactive Protein and Peritoneal Cytokines as Early Predictors of Anastomotic Leak after Colorectal Surgery

  • Dubravka Mužina,
  • Mario Kopljar,
  • Zdenko Bilić,
  • Blaženka Ladika Davidović,
  • Goran Glavčić,
  • Suzana Janković and
  • Monika Mačkić

23 September 2024

Objectives: The aim of this study was to evaluate the accuracy of serum C-reactive protein (CRP) and intraperitoneal CRP, interleukin-6, and tumor necrosis factor-alpha in early diagnostics of anastomotic leakage in the first 4 postoperative days aft...

  • Article
  • Open Access
303 Views
14 Pages

Felt Versus Pericardium for the Sandwich Technique in Type A Aortic Dissection: A Human Cadaver Study

  • Jasmine El-Nashar,
  • Thomas Poschner,
  • Mohamed El Din,
  • Paata Pruidze,
  • Giorgi Didava,
  • Amila Kahrovic,
  • Wolfgang J. Weninger,
  • Daniel Zimpfer,
  • Marek P. Ehrlich and
  • Emilio Osorio-Jaramillo

31 October 2025

Background: The Sandwich technique is a commonly adopted method for reinforcing the dissected aortic wall during acute Type A aortic dissection (ATAAD) repair, using either felt or bovine pericardial strips. However, complications such as anastomotic...

  • Article
  • Open Access
1 Citations
1,658 Views
13 Pages

Influence of Neoadjuvant Therapy on Success of Endoscopic Vacuum Therapy in Anastomotic Leakage after Rectal Resection Because of Rectal Cancer

  • Rahel M. Strobel,
  • Julia E. Wellner,
  • Konrad Neumann,
  • Susanne D. Otto,
  • Sophie M. Eschlboeck,
  • Claudia Seifarth,
  • Christian H. W. Schineis,
  • Katharina Beyer,
  • Martin E. Kreis and
  • Johannes C. Lauscher

8 July 2024

Background: For locally advanced rectal cancer, neoadjuvant therapy (NT) is an established element of therapy. Endoscopic vacuum therapy (EVT) has been a relevant treatment option for anastomotic leakage after rectal resection since 2008. The aim was...

  • Article
  • Open Access
1 Citations
2,174 Views
14 Pages

Evaluation of Key Risk Factors Associated with Postoperative Complications in Colorectal Cancer Surgery

  • Silviu Stefan Marginean,
  • Mihai Zurzu,
  • Dragos Garofil,
  • Anca Tigora,
  • Vlad Paic,
  • Mircea Bratucu,
  • Florian Popa,
  • Valeriu Surlin,
  • Dan Cartu and
  • Victor Strambu
  • + 1 author

Background: Colorectal surgery remains a cornerstone in the management of colorectal cancer, yet postoperative complications continue to impact surgical outcomes. This study investigates key risk factors influencing morbidity, focusing on patient com...

  • Systematic Review
  • Open Access
15 Citations
2,831 Views
10 Pages

The Role of Indocyanine Green Fluorescence in Rectal Cancer Robotic Surgery: A Narrative Review

  • Elena Belloni,
  • Edoardo Maria Muttillo,
  • Salomone Di Saverio,
  • Marcello Gasparrini,
  • Antonio Brescia and
  • Giuseppe Nigri

13 May 2022

Background: In rectal cancer surgery, anastomotic leakage (AL) remains the most feared complication, with a frequency of up to 30% in non-high-volume centers. The preservation of proper vascularization is a key factor for successful anastomosis. The...

  • Article
  • Open Access
4 Citations
2,213 Views
10 Pages

Management of Anastomotic Leakage after Colorectal Resection: Survey among the German CHIR-Net Centers

  • Flavius Șandra-Petrescu,
  • Nuh N. Rahbari,
  • Emrullah Birgin,
  • Konstantinos Kouladouros,
  • Peter Kienle,
  • Christoph Reissfelder,
  • Emmanouil Tzatzarakis and
  • Florian Herrle

27 July 2023

(1) Background: A widely accepted algorithm for the management of colorectal anastomotic leakage (CAL) is difficult to establish. The present study aimed to evaluate the current clinical practice on the management of CAL among the German CHIR-Net cen...

  • Article
  • Open Access
6 Citations
3,015 Views
20 Pages

Microbiota Phenotype Promotes Anastomotic Leakage in a Model of Rats with Ischemic Colon Resection

  • Diego Zamorano,
  • Dinka Ivulic,
  • Tomeu Viver,
  • Felipe Morales,
  • Francisco López-Kostner and
  • Roberto M. Vidal

Anastomotic leakage (AL) is a major cause of morbidity and mortality after colorectal surgery, but the mechanism behind this complication is still not fully understood. Despite the advances in surgical techniques and perioperative care, the complicat...

  • Article
  • Open Access
6 Citations
8,057 Views
10 Pages

Aim: An anastomotic leak is an unpredictable postoperative complication during recovery from colorectal surgery that may require a re-operation. Potentially pathogenic bacteria like Pseudomonas (and Enterococcus) contribute to the pathogenesis of an...

  • Article
  • Open Access
1 Citations
2,687 Views
8 Pages

Measurement of Suture Pullout Forces of the Pancreatic Duct and Capsule

  • Alex T. Gong,
  • Sophia L. Bidinger,
  • Aleah M. DeSchmidt,
  • Joaquin E. Batista,
  • Agnes Y. Song,
  • Alyssa L. Schul,
  • Everet Y. Wang,
  • Jack E. Norfleet,
  • Martin E. Palavecino and
  • Robert M. Sweet

A thorough biomechanical understanding of human organs is of increasing importance for designing and improving a wide range of medical technologies from simulators to medical devices. Despite the crucial need for data, little procedure-specific biome...

  • Article
  • Open Access
2,496 Views
8 Pages

Is Hartmann’s Pouch an Option in the Management of Acute Severe Ulcerative Colitis?

  • Myriam Renaud,
  • Ahmet Ayav,
  • Bénédicte Caron,
  • Laurent Peyrin-Biroulet and
  • Adeline Germain

3 July 2022

Background: The surgical management of remnant rectosigmoid after subtotal colectomy with end ileostomy for acute severe ulcerative colitis remains controversial with respect to the need to perform sigmoidostomy or Hartmann’s pouch. The aim of this r...

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