You are currently viewing a new version of our website. To view the old version click .

4,125 Results Found

  • Review
  • Open Access
358 Citations
29,484 Views
31 Pages

Most bacteria attach to biotic or abiotic surfaces and are embedded in a complex matrix which is known as biofilm. Biofilm formation is especially worrisome in clinical settings as it hinders the treatment of infections with antibiotics due to the fa...

  • Review
  • Open Access
1 Citations
2,688 Views
23 Pages

Antibiotic Resistance Gene Expression in Veterinary Probiotics: Two Sides of the Coin

  • Ádám Kerek,
  • István Román,
  • Ábel Szabó,
  • Nikolett Palkovicsné Pézsa and
  • Ákos Jerzsele

2 March 2025

The rapid proliferation of antimicrobial resistance has emerged as one of the most pressing animal and public health challenges of our time. Probiotics, extensively employed in human and veterinary medicine, are instrumental in maintaining a balanced...

  • Article
  • Open Access
8 Citations
3,051 Views
15 Pages

Novel Antibiotic Resistance Genes Identified by Functional Gene Library Screening in Stenotrophomonas maltophilia and Chryseobacterium spp. Bacteria of Soil Origin

  • Laurita Klimkaitė,
  • Ignas Ragaišis,
  • Renatas Krasauskas,
  • Modestas Ružauskas,
  • Edita Sužiedėlienė and
  • Julija Armalytė

As one of the most diverse habitats of microorganisms, soil has been recognised as a reservoir of both antibiotics and the antibiotic resistance genes (ARGs). Bacteria naturally inhabiting soil or water often possess innate ARGs to counteract the che...

  • Article
  • Open Access
14 Citations
4,044 Views
18 Pages

The continuous spread of antimicrobial resistance is endangering the efficient control of enterotoxigenic Escherichia coli (ETEC), which is mainly responsible for post-weaning diarrhea onset in piglets. Thymol, the key constituent of thyme essential...

  • Article
  • Open Access
8 Citations
3,940 Views
16 Pages

Bacterial Community and Antibiotic Resistance Gene Profiles of Fish Gut Contents and Their Aquaculture Environment in Tianjin, China

  • Qiushui Wang,
  • Xin Zhou,
  • Yue Liu,
  • Qi Ding,
  • Zan Wu,
  • Jie Deng,
  • Jia Zuo,
  • Liyan Yuan,
  • Peng Shao and
  • Bo Cheng
  • + 1 author

2 November 2022

The continuous expansion of freshwater fish culture is confronted with environmental problems owing to their high antibiotic inputs and antibiotic-resistant bacteria. This study explored the antibiotic resistance gene (ARG) profiles of water and fish...

  • Article
  • Open Access
4 Citations
1,452 Views
20 Pages

2 December 2024

The study aimed to assess the high-pressure processing (HPP) impact on antibiotic resistance gene transfer in L. monocytogenes from food and food processing environments, both in vitro (in microbiological medium) and in situ (in carrot juice), using...

  • Article
  • Open Access
10 Citations
4,538 Views
14 Pages

31 March 2023

Antibiotic resistance is a critical problem that results in a high morbidity and mortality rate. The process of discovering new chemotherapy and antibiotics is challenging, expensive, and time-consuming, with only a few getting approved for clinical...

  • Article
  • Open Access
932 Views
21 Pages

Bacterivorous Ciliate Tetrahymena pyriformis Facilitates vanA Antibiotic Resistance Gene Transfer in Enterococcus faecalis

  • Temilola O. Olanrewaju,
  • James S. G. Dooley,
  • Heather M. Coleman,
  • Chris McGonigle and
  • Joerg Arnscheidt

Background: Wastewater treatment plants (WWTPs) are hotspots for the emergence and spread of antibiotic resistance genes (ARGs). In activated sludge treatment systems, bacterivorous protozoa play a crucial role in biological processes, yet their impa...

  • Article
  • Open Access
2 Citations
1,147 Views
25 Pages

29 July 2025

Antibiotic resistance genes (ARGs) in suburban freshwater ecosystems pose a growing public health concern by potentially reducing the effectiveness of medical treatments. This study investigated how rainfall influences ARG dynamics in Lake Katherine,...

  • Article
  • Open Access
941 Views
18 Pages

Effects of Antibiotic Residues on Fecal Microbiota Composition and Antimicrobial Resistance Gene Profiles in Cattle from Northwestern China

  • Wei He,
  • Xiaoming Wang,
  • Yuying Cao,
  • Cong Liu,
  • Zihui Qin,
  • Yang Zuo,
  • Yiming Li,
  • Fang Tang,
  • Jianjun Dai and
  • Shaolin Wang
  • + 1 author

Grazing is a free-range farming model commonly practiced in low-external-input agricultural systems. The widespread use of veterinary antibiotics in livestock farming has led to significant environmental accumulation of antibiotic residues and antibi...

  • Communication
  • Open Access
10 Citations
5,110 Views
7 Pages

31 December 2020

The development of new antibacterial drugs has become one of the most important tasks of the century in order to overcome the posing threat of drug resistance in pathogenic bacteria. Many antibiotics originate from natural products produced by variou...

  • Article
  • Open Access
14 Citations
5,593 Views
18 Pages

Exploring Antibiotic Resistance Diversity in Leuconostoc spp. by a Genome-Based Approach: Focus on the lsaA Gene

  • Elisa Salvetti,
  • Ilenia Campedelli,
  • Ilaria Larini,
  • Giada Conedera and
  • Sandra Torriani

Leuconostoc spp. are environmental microorganisms commonly associated with fermented foods. Absence of antibiotic resistance (AR) in bacteria is a critical issue for global food safety. Herein, we updated the occurrence of AR genes in the Leuconostoc...

  • Article
  • Open Access
36 Citations
6,114 Views
15 Pages

Antibiotic Resistance and Virulence Gene Patterns Associated with Avian Pathogenic Escherichia coli (APEC) from Broiler Chickens in Qatar

  • Alreem Johar,
  • Najlaa Al-Thani,
  • Sara H. Al-Hadidi,
  • Elyes Dlissi,
  • Mahmoud H. Mahmoud and
  • Nahla O. Eltai

Avian Pathogenic Escherichia coli (APEC) is the contributing agent behind the avian infectious disease colibacillosis, which causes substantial fatalities in poultry industries that has a significant impact on the economy and food safety. Several vir...

  • Article
  • Open Access
945 Views
13 Pages

3 April 2025

Earthworm gut digestion plays a crucial role in reducing antibiotic resistance genes (ARGs) during vermicomposting, offering significant potential for controlling ARG dissemination in livestock manure. However, the impact of residual tetracycline ant...

  • Article
  • Open Access
4 Citations
864 Views
5 Pages

Prevalence of Antibiotic Resistance and blaIMP-1 Gene among Pseudomonas aeruginosa Strains Isolated from Burn and Urinary Tract Infections in Isfahan, Central Iran

  • Naeimeh Sadat Hashemi,
  • Meysam Mojiri,
  • Parivash Yazdani Kachouyi,
  • Shiva Eskandari,
  • Mehrsa Mohammadian and
  • Iman Alavi

7 November 2017

Pseudomonas aeruginosa is one of the most important opportunistic pathogens responsible for various types of hospital infections. High prevalence of antibiotic resistance in P. aeruginosa strains of human clinical samples cause more severe diseases f...

  • Article
  • Open Access
3 Citations
2,386 Views
12 Pages

Biofilm is considered as the hotspot of antibiotic resistance gene (ARG) dissemination. Bacterial growth substrates are important factors for biofilm formation, but its spatial–temporal effects on ARG spread in biofilm is still unclear. In this...

  • Article
  • Open Access
1 Citations
3,140 Views
14 Pages

20 August 2021

The research herein explored the possible mechanism of toxicity of the antibiotic sulfadiazine (SD) and the related antibiotic resistance gene transformation in lettuce by systematically investigating its growth responses, ultrastructural changes, an...

  • Article
  • Open Access
53 Citations
5,254 Views
13 Pages

Human infections with Campylobacter are primarily associated with the consumption of contaminated poultry meat. In this study, we isolated Campylobacter jejuni from retail raw chicken and duck meat in Korea and compared their aerotolerance, antibioti...

  • Article
  • Open Access
14 Citations
4,148 Views
22 Pages

Non-Clinical In Vitro Evaluation of Antibiotic Resistance Gene-Free Plasmids Encoding Human or Murine IL-12 Intended for First-in-Human Clinical Study

  • Spela Kos,
  • Masa Bosnjak,
  • Tanja Jesenko,
  • Bostjan Markelc,
  • Urska Kamensek,
  • Katarina Znidar,
  • Urska Matkovic,
  • Andrej Rencelj,
  • Gregor Sersa and
  • Rosana Hudej
  • + 3 authors

Interleukin 12 (IL-12) is a key cytokine that mediates antitumor activity of immune cells. To fulfill its clinical potential, the development is focused on localized delivery systems, such as gene electrotransfer, which can provide localized delivery...

  • Article
  • Open Access
16 Citations
3,428 Views
20 Pages

Removal of Antibiotic Resistance Genes, Class 1 Integrase Gene and Escherichia coli Indicator Gene in a Microalgae-Based Wastewater Treatment System

  • Abdullahi B. Inuwa,
  • Qaisar Mahmood,
  • Jamshed Iqbal,
  • Emilie Widemann,
  • Sarfraz Shafiq,
  • Muhammad Irshad,
  • Usman Irshad,
  • Akhtar Iqbal,
  • Farhan Hafeez and
  • Rashid Nazir

2 November 2022

Microalgae-based wastewater treatment systems (AWWTS) have recently shown promise in the mitigation of antibiotic resistance genes (ARGs) from municipal wastewater (MWW). However, due to the large number of ARGs that exist in MWW, the use of indirect...

  • Article
  • Open Access
399 Views
19 Pages

5 November 2025

Antibiotic resistance genes (ARGs) are regarded as a major threat to public health and ecological security globally. The Dongliao River Basin is a typical farming–pastoral ecotone in the northeast of China. It is of great practical significance...

  • Article
  • Open Access
76 Citations
9,562 Views
11 Pages

Antibiotic Resistance and Antibiotic Resistance Genes in Escherichia coli Isolates from Hospital Wastewater in Vietnam

  • La Thi Quynh Lien,
  • Pham Thi Lan,
  • Nguyen Thi Kim Chuc,
  • Nguyen Quynh Hoa,
  • Pham Hong Nhung,
  • Nguyen Thi Minh Thoa,
  • Vishal Diwan,
  • Ashok J. Tamhankar and
  • Cecilia Stålsby Lundborg

The environmental spread of antibiotic-resistant bacteria has been recognised as a growing public health threat for which hospitals play a significant role. The aims of this study were to investigate the prevalence of antibiotic resistance and antibi...

  • Article
  • Open Access
8 Citations
3,715 Views
16 Pages

Gut microbiomes play important functional roles in human health and are also affected by many factors. However, few studies concentrate on gut microbiomes under exercise intervention. Additionally, antibiotic resistance genes (ARGs) carried by gut mi...

  • Review
  • Open Access
18 Citations
14,951 Views
34 Pages

Acquired Bacterial Resistance to Antibiotics and Resistance Genes: From Past to Future

  • Michela Galgano,
  • Francesco Pellegrini,
  • Elisabetta Catalano,
  • Loredana Capozzi,
  • Laura Del Sambro,
  • Alessio Sposato,
  • Maria Stella Lucente,
  • Violetta Iris Vasinioti,
  • Cristiana Catella and
  • Amienwanlen Eugene Odigie
  • + 3 authors

21 February 2025

The discovery, commercialization, and regular administration of antimicrobial agents have revolutionized the therapeutic paradigm, making it possible to treat previously untreatable and fatal infections. However, the excessive use of antibiotics has...

  • Review
  • Open Access
58 Citations
10,718 Views
22 Pages

Antibiotic Resistance in the Drinking Water: Old and New Strategies to Remove Antibiotics, Resistant Bacteria, and Resistance Genes

  • Ana Catarina Duarte,
  • Sílvia Rodrigues,
  • Andrea Afonso,
  • António Nogueira and
  • Paula Coutinho

24 March 2022

Bacterial resistance is a naturally occurring process. However, bacterial antibiotic resistance has emerged as a major public health problem in recent years. The accumulation of antibiotics in the environment, including in wastewaters and drinking wa...

  • Review
  • Open Access
122 Citations
14,203 Views
14 Pages

30 April 2023

Antibiotics are commonly used to prevent and control diseases in aquaculture. However, long-term/overuse of antibiotics not only leaves residues but results in the development of antibiotic resistant bacteria (ARB) and antibiotic resistance genes (AR...

  • Communication
  • Open Access
27 Citations
4,438 Views
10 Pages

Antibiotic Resistance Genes Occurrence in Conventional and Antibiotic-Free Poultry Farming, Italy

  • Muhammad Farooq,
  • Camilla Smoglica,
  • Fausto Ruffini,
  • Lidia Soldati,
  • Fulvio Marsilio and
  • Cristina E. Di Francesco

6 September 2022

Antimicrobial resistance is a complex and widespread problem threatening human and animal health. In poultry farms, a wide distribution of resistant bacteria and their relative genes is described worldwide, including in Italy. In this paper, a compar...

  • Communication
  • Open Access
4 Citations
2,052 Views
11 Pages

Wastewater storage before reuse is regulated in some countries. Investigations of pathogens and antibiotic resistance genes (ARGs) during wastewater storage are necessary for lowering the risks for wastewater reuse but are still mostly lacking. This...

  • Article
  • Open Access
87 Citations
16,902 Views
18 Pages

4 January 2018

Wastewater treatment plants (WWTPs) have been identified as potential sources of antibiotic resistance genes (ARGs) but the effects of tertiary wastewater treatment processes on ARGs have not been well characterized. Therefore, the objective of this...

  • Article
  • Open Access
31 Citations
5,793 Views
15 Pages

The removal of antibiotics and widespread of antibiotic resistance genes (ARGs) have received continuous attention due to the possible threats to environment. However, little information is available on the evolution of antibiotic resistance and the...

  • Article
  • Open Access
3,306 Views
18 Pages

Comprehensive Study of Antibiotics and Antibiotic Resistance Genes in Wastewater and Impacted Mediterranean Water Environments

  • Maria Garcia-Torné,
  • Irene Falcó,
  • Xavier Borrell,
  • Arianna Bautista,
  • Rachida Mazigh,
  • Rosa Aznar,
  • Gloria Sánchez,
  • Marinella Farré and
  • Marta Llorca

Background: The spread of antimicrobial resistance is a central public health problem. Wastewater treatment plants and impacted environments are well-known hotspots for antibiotic resistance. However, there is still limited knowledge regarding where...

  • Review
  • Open Access
4 Citations
3,245 Views
18 Pages

10 February 2023

The reuse of household greywater is increasing globally. Wastewater and greywater treatment processes are not fully effective in removing all contaminants, such as emerging micropollutants, antimicrobial-resistant bacteria, and antibiotic resistance...

  • Article
  • Open Access
10 Citations
2,853 Views
15 Pages

Low Concentrations of Antibiotics Alter Microbial Communities and Induce High Abundances of Antibiotic-Resistant Genes in Ornamental Water

  • Lingyun Tian,
  • Hao Fang,
  • Qianbo Mao,
  • Yi Bai,
  • Zirui Ye,
  • Dingjun Hu,
  • Xiaoheng Wang,
  • Yiyu Hou,
  • Nan Ye and
  • Shuai Zhang
  • + 1 author

25 August 2023

Antibiotic resistance poses a significant threat to the public health domain. A favorable platform for generating and disseminating antibiotic-resistant genes (ARGs) and antibiotic-resistant bacteria (ARB) is provided by landscaped fish ponds created...

  • Article
  • Open Access
13 Citations
3,350 Views
13 Pages

Antibiotic-Resistant Escherichia coli Strains Isolated from Captive Giant Pandas: A Reservoir of Antibiotic Resistance Genes and Virulence-Associated Genes

  • Siping Fan,
  • Shaoqi Jiang,
  • Lijun Luo,
  • Ziyao Zhou,
  • Liqin Wang,
  • Xiangming Huang,
  • Haifeng Liu,
  • Shaqiu Zhang,
  • Yan Luo and
  • Zhihua Ren
  • + 14 authors

18 December 2022

Recent studies showed that Escherichia coli (E. coli) strains isolated from captive giant pandas have serious resistance to antibiotics and carry various antibiotic resistance genes (ARGs). ARGs or virulence-associated genes (VAGs) carried by antibio...

  • Article
  • Open Access
70 Citations
9,438 Views
16 Pages

Seasonal Variations in Water-Quality, Antibiotic Residues, Resistant Bacteria and Antibiotic Resistance Genes of Escherichia coli Isolates from Water and Sediments of the Kshipra River in Central India

  • Vishal Diwan,
  • Nada Hanna,
  • Manju Purohit,
  • Salesh Chandran,
  • Emilia Riggi,
  • Vivek Parashar,
  • Ashok J. Tamhankar and
  • Cecilia Stålsby Lundborg

Objectives: To characterize the seasonal variation, over one year, in water-quality, antibiotic residue levels, antibiotic resistance genes and antibiotic resistance in Escherichia coli isolates from water and sediment of the Kshipra River in Central...

  • Review
  • Open Access
40 Citations
10,551 Views
25 Pages

The rapidly emerging phenomenon of antibiotic resistance threatens to substantially reduce the efficacy of available antibacterial therapies. Dissemination of resistance, even between phylogenetically distant bacterial species, is mediated mainly by...

  • Review
  • Open Access
80 Citations
11,424 Views
14 Pages

Due to selective pressure from the widespread use of antibiotics, antibiotic resistance genes (ARGs) are found in human hosts, plants, and animals and virtually all natural environments. Their migration and transmission in different environmental med...

  • Article
  • Open Access
3 Citations
1,597 Views
17 Pages

Evolution of the Antibiotic Resistance Levels, Multi-Resistance Patterns, and Presence of Antibiotic Resistance Genes in E. coli Isolates from the Feces of Breeding Hens during the Rearing Period

  • Alejandro Fenollar-Penadés,
  • Pablo Catalá-Gregori,
  • Vicente Tallá-Ferrer,
  • María Ángeles Castillo,
  • Miguel García-Ferrús and
  • Ana Jiménez-Belenguer

The food chain acts as an entry point for antibiotic resistance to reach humans and environment. Because of the importance of the poultry sector, we investigated the prevalence and evolution of antibiotic resistance in Escherichia coli isolates from...

  • Article
  • Open Access
6 Citations
3,438 Views
28 Pages

Linking Antibiotic Residues and Antibiotic Resistance Genes to Water Quality Parameters in Urban Reservoirs: A Seasonal Perspective

  • Sihan Li,
  • Raphinos Tackmore Murava,
  • Qiyue Zhang,
  • Tong Zhou,
  • Armstrong Ighodalo Omoregie,
  • Adharsh Rajasekar and
  • Tariq Ouahbi

The interaction between antibiotics and antibiotic resistance genes (ARGs) in freshwater ecosystems has become a critical environmental concern. This study investigates seasonal variations of sulfonamide and tetracycline antibiotics and their relatio...

  • Review
  • Open Access
42 Citations
10,701 Views
28 Pages

31 May 2023

Antimicrobial resistance (AMR) is a serious problem for modern society, not only associated with clinical environments, but also the natural environment. Conventional wastewater treatment plants (WWTPs) are important nodes for the dissemination of an...

  • Article
  • Open Access
39 Citations
6,495 Views
11 Pages

3 July 2020

The proliferation of antibiotic-resistant bacteria (ARB) and the prevalence of antibiotic resistance genes (ARGs) in wastewaters are well-established factors that contribute to the reduced potency of antibiotics used in healthcare worldwide. The huma...

  • Article
  • Open Access
2 Citations
2,459 Views
9 Pages

Antibiotic Resistance Genes Detection in Several Local Cyanobacteria Isolates

  • Harith K. Buniya,
  • Nuha A. Mohammed and
  • Dhyauldeen Aftan Al-Hayani

23 November 2024

Antibiotic resistance in cyanobacteria represents a global threat to public health. The widespread presence of cyanobacteria in aquatic environments exposes them to antibiotic contamination. Cyanobacteria are also in direct contact with pathogenic ba...

  • Article
  • Open Access
61 Citations
8,757 Views
18 Pages

The exposure of both crop fields and humans to antibiotic-resistant bacteria in animal excreta is an emergent concern of the One Health initiative. This study assessed the contamination of livestock manure from poultry, pig, dairy farms and slaughter...

  • Article
  • Open Access
10 Citations
4,320 Views
16 Pages

Characterization of Antibiotic Resistant Coliform Bacteria and Resistance Genes Isolated from Samples of Smoothie Drinks and Raw Milk

  • Monika Krahulcová,
  • Klára Cverenkárová,
  • Petra Olejníková,
  • Barbora Micajová,
  • Júlia Koreneková and
  • Lucia Bírošová

1 May 2022

Raw foodstuffs have been marked as a healthier alternative in the context of nutrient content and are becoming more popular with consumers. Thermally untreated foods may represent a microbiological risk connected with the possible presence of antimic...

  • Article
  • Open Access
5 Citations
1,804 Views
15 Pages

Identification and Distribution of Antibiotic Resistance Genes and Antibiotic Resistance Bacteria in the Feces Treatment Process: A Case Study in a Dairy Farm, China

  • Hailun Wang,
  • Yongchao Gao,
  • Liwen Zheng,
  • Lei Ji,
  • Xue Kong,
  • Jianhua Du,
  • Hui Wang,
  • Luchun Duan,
  • Tian Niu and
  • Jianhui Liu
  • + 1 author

31 May 2024

The overuse of antibiotics has resulted in the prevalence of antibiotic resistance genes (ARGs) and antibiotic resistance bacteria (ARB) in the environment. High-density livestock farming is one of the major industries for antibiotic overuse. In this...

  • Article
  • Open Access
33 Citations
6,969 Views
14 Pages

26 November 2019

Effluents from wastewater treatment plants has been identified as a main point-source of antibiotics and antibiotic resistance genes in natural water environments. In this study, a typical municipal sewage treatment system in south China was taken as...

  • Article
  • Open Access
19 Citations
3,331 Views
15 Pages

8 November 2021

Background: Antibiotics releasing from the manufacturing sites to the surrounding environment has been identified as a risk factor for the development of antibiotic resistance of bacterial pathogens. However, the knowledge of the abundance and distri...

  • Article
  • Open Access
30 Citations
7,925 Views
9 Pages

Inactivation Effect of Antibiotic-Resistant Gene Using Chlorine Disinfection

  • Takashi Furukawa,
  • Atsushi Jikumaru,
  • Takahisa Ueno and
  • Kazunari Sei

21 July 2017

The aim of this study was to elucidate the inactivation effects on the antibiotic-resistance gene (vanA) of vancomycin-resistant enterococci (VRE) using chlorination, a disinfection method widely used in various water treatment facilities. Suspension...

  • Article
  • Open Access
17 Citations
4,399 Views
11 Pages

Prevalence of Antibiotic Resistance Genes in Pharmaceutical Wastewaters

  • Amarachukwu Obayiuwana,
  • Adeniyi Ogunjobi and
  • Abasiofiok Ibekwe

23 June 2021

Pharmaceutical wastewaters are recognized as reservoirs of antibiotic resistance genes (ARGs) and antibiotic resistant bacteria (ARB), and also as hotspots for their horizontal gene transfer (HGT) using mobile genetic elements. Our study employed the...

  • Article
  • Open Access
10 Citations
3,238 Views
12 Pages

Antibiotic resistance is an issue in many areas of human activity. The mobilization of antibiotic resistance genes within the bacterial community makes it difficult to study and control the phenomenon. It is known that certain insertion sequences, wh...

of 83