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4 Results Found

  • Review
  • Open Access
4 Citations
3,778 Views
9 Pages

Ovarian Stem Cells for Women’s Infertility: State of the Art

  • Krzysztof Grettka,
  • Katarzyna Idzik,
  • Katarzyna Lewandowska,
  • Ksena Świętek,
  • Simone Palini and
  • Franco Silvestris

Today, women’s infertility is considered a social disease in females, occurring not only as an effect of POF (premature ovarian failure) but also as CTRI (cancer treatment-related infertility) in oncologic patients. Several procedures for FP (f...

  • Review
  • Open Access
7 Citations
4,131 Views
12 Pages

Ovarian Stem Cells (OSCs) from the Cryopreserved Ovarian Cortex: A Potential for Neo-Oogenesis in Women with Cancer-Treatment Related Infertility: A Case Report and a Review of Literature

  • Erica Silvestris,
  • Carla Minoia,
  • Attilio Guarini,
  • Giuseppina Opinto,
  • Antonio Negri,
  • Miriam Dellino,
  • Raffaele Tinelli,
  • Gennaro Cormio,
  • Angelo Virgilio Paradiso and
  • Giuseppe De Palma

Cancer treatment related infertility (CTRI) affects more than one third of young women undergoing anti-cancer protocols, inducing a premature exhaustion of the ovarian reserve. In addition to ovarian suppression by GnRHa, oocyte and cortex cryopreser...

  • Brief Report
  • Open Access
1,641 Views
9 Pages

Optimizing the Ovarian Tissue Cryopreservation in the ‘Oncofertility’ Institutional Program at an Italian National Cancer Institute

  • Erica Silvestris,
  • Carla Minoia,
  • Giuseppe De Palma,
  • Ondina Popescu,
  • Anna Altavilla,
  • Attilio Guarini,
  • Fabio Pavone,
  • Vera Loizzi,
  • Gennaro Cormio and
  • Raffaella Depalo

13 October 2023

Background: The majority of female cancer patients undergoing anticancer treatments are at risk of experiencing ‘cancer treatment-related infertility’, which can result in permanent damage to their reproductive prospects. Among the fertil...

  • Review
  • Open Access
1 Citations
4,122 Views
14 Pages

Fertility Preservation in BRCA1/2 Germline Mutation Carriers: An Overview

  • Erica Silvestris,
  • Gennaro Cormio,
  • Vera Loizzi,
  • Giacomo Corrado,
  • Francesca Arezzo and
  • Easter Anna Petracca

10 May 2024

BRCA1 and BRCA2 mutations are responsible for a higher incidence of breast and ovarian cancer (from 55% up to 70% vs. 12% in the general population). If their functions have been widely investigated in the onset of these malignancies, still little is...