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354 Results Found

  • Article
  • Open Access
17 Citations
1,363 Views
5 Pages

Labor epidural analgesia and the incidence of instrumental assisted delivery

  • Kęstutis Rimaitis,
  • Olga Klimenko,
  • Marius Rimaitis,
  • Asta Morkūnaitė and
  • Andrius Macas

25 March 2015

Objective: To assess the influence of labor epidural analgesia on the course of labor and to determine its association with instrumental assisted delivery rate. Materials and methods: A retrospective case–control study was performed during 2007–2011...

  • Systematic Review
  • Open Access
7 Citations
6,694 Views
21 Pages

Influence of Physical Activity during Pregnancy on Type and Duration of Delivery, and Epidural Use: Systematic Review and Meta-Analysis

  • Dingfeng Zhang,
  • Stephanie-May Ruchat,
  • Cristina Silva-Jose,
  • Javier Gil-Ares,
  • Rubén Barakat and
  • Miguel Sánchez-Polán

5 August 2023

Cesarean delivery may increase the need for anesthesia administration, thereby causing potential risks to both maternal and fetal health. This article aimed to investigate the effect of physical activity during pregnancy on the type of delivery, the...

  • Article
  • Open Access
116 Citations
10,613 Views
27 Pages

Double Optimization of Rivastigmine-Loaded Nanostructured Lipid Carriers (NLC) for Nose-to-Brain Delivery Using the Quality by Design (QbD) Approach: Formulation Variables and Instrumental Parameters

  • Sara Cunha,
  • Cláudia Pina Costa,
  • Joana A. Loureiro,
  • Jorge Alves,
  • Andreia F. Peixoto,
  • Ben Forbes,
  • José Manuel Sousa Lobo and
  • Ana Catarina Silva

Rivastigmine is a drug commonly used in the management of Alzheimer’s disease that shows bioavailability problems. To overcome this, the use of nanosystems, such as nanostructured lipid carriers (NLC), administered through alternative routes se...

  • Article
  • Open Access
1,458 Views
15 Pages

The Development of a Forceps-Adaptable Pressure Device for Instrumental Delivery: A Proof-of-Concept Study for Clinical and Educational Applications

  • Mathieu Hivert,
  • Cyril Bengler,
  • Julien De Jonckheere,
  • Franck Gaultier,
  • Marie Pécout,
  • Olivier Mayeur and
  • Chrystèle Rubod

8 December 2024

Objective: To develop and validate a device that measures the pressure exerted by forceps on the fetal head for clinical use. Background: The lack of clinical tools to quantify forceps pressure on the fetal head may impact maternal and neonatal outco...

  • Article
  • Open Access
4 Citations
2,721 Views
23 Pages

Operative Vaginal delivery (OVD) can reduce perinatal and maternal morbidity and mortality especially in low resource setting such as South Africa. We evaluated the trends and determinants of OVD rates using join point regression at Charlotte Maxeke...

  • Systematic Review
  • Open Access
15 Citations
2,942 Views
21 Pages

Assisted Reproductive Technique and Abnormal Cord Insertion: A Systematic Review and Meta-Analysis

  • Shinya Matsuzaki,
  • Yutaka Ueda,
  • Satoko Matsuzaki,
  • Yoshikazu Nagase,
  • Mamoru Kakuda,
  • Misooja Lee,
  • Michihide Maeda,
  • Hiroki Kurahashi,
  • Harue Hayashida and
  • Tsuyoshi Hisa
  • + 2 authors

Abnormal cord insertion (ACI) is associated with adverse obstetric outcomes; however, the relationship between ACI and assisted reproductive technology (ART) has not been examined in a meta-analysis. This study examines the association between ACI an...

  • Article
  • Open Access
2 Citations
3,150 Views
10 Pages

The Logarithmic Spiral Neutron Guide

  • Christine Klauser and
  • Jochen Stahn

We present a neutron guide which is curved in the shape of a logarithmic spiral. Simulations and calculations for such a spiral guide are presented and the potential use of the guide for a reflectometer is investigated and compared to the conventiona...

  • Perspective
  • Open Access
17 Citations
4,733 Views
12 Pages

Potential of Time-Resolved Serial Femtosecond Crystallography Using High Repetition Rate XFEL Sources

  • Raphaël de Wijn,
  • Diogo V. M. Melo,
  • Faisal H. M. Koua and
  • Adrian P. Mancuso

28 February 2022

This perspective review describes emerging techniques and future opportunities for time-resolved serial femtosecond crystallography (TR-SFX) experiments using high repetition rate XFEL sources. High repetition rate sources are becoming more available...

  • Article
  • Open Access
9 Citations
5,648 Views
16 Pages

Tablets Made from Paper—An Industrially Feasible Approach

  • Ayat Abdelkader,
  • Christoph Moos,
  • Adrien Pelloux,
  • Marcus Pfeiffer,
  • Christian Alter,
  • Stefan Kolling and
  • Cornelia M. Keck

26 September 2022

Many orally administrated drugs exhibit poor bioavailability due to their limited solubility. The smartFilm technology is an innovative approach to improve the drug aqueous solubility, where the drug is embedded within the matrix of cellulose-based p...

  • Systematic Review
  • Open Access
13 Citations
3,393 Views
18 Pages

Association between Endometriosis and Delivery Outcomes: A Systematic Review and Meta-Analysis

  • Yoshikazu Nagase,
  • Shinya Matsuzaki,
  • Yutaka Ueda,
  • Mamoru Kakuda,
  • Sahori Kakuda,
  • Hitomi Sakaguchi,
  • Michihide Maeda,
  • Tsuyoshi Hisa and
  • Shoji Kamiura

Endometriosis is a common benign gynecological disorder; however, delivery outcomes concerning pregnancies with endometriosis remain understudied. This study aimed to assess the effect of endometriosis on delivery outcomes, including the rate of inst...

  • Article
  • Open Access
13 Citations
4,605 Views
10 Pages

Epidural Analgesia and Neonatal Morbidity: A Retrospective Cohort Study

  • Antonio Hernández Martínez,
  • Julián Javier Rodríguez Almagro,
  • María Moreno-Cid García-Suelto,
  • María Ureña Barrajon,
  • Milagros Molina Alarcón and
  • Juan Gómez-Salgado

(1) Background: Epidural analgesia (EA), at the present time, is one of the most effective methods to reduce labor pain. In recent years its use has increased, being used between 20–70% of all deliveries; (2) Methods: Historical cohort on a tot...

  • Review
  • Open Access
4 Citations
3,863 Views
28 Pages

Ultrasound-Mediated Ocular Drug Delivery: From Physics and Instrumentation to Future Directions

  • Blair Duncan,
  • Raida Al-Kassas,
  • Guangming Zhang,
  • Dave Hughes and
  • Yongqiang Qiu

9 August 2023

Drug delivery to the anterior and posterior segments of the eye is impeded by anatomical and physiological barriers. Increasingly, the bioeffects produced by ultrasound are being proven effective for mitigating the impact of these barriers on ocular...

  • Article
  • Open Access
5 Citations
4,242 Views
12 Pages

Symptoms of Discomfort and Problems Associated with Mode of Delivery During the Puerperium: An Observational Study

  • Juan Miguel Martínez-Galiano,
  • Miguel Delgado-Rodríguez,
  • Julián Rodríguez-Almagro and
  • Antonio Hernández-Martínez

Despite abundant literature on antenatal and delivery care received by pregnant women, there is a wide knowledge gap on the prevalence of symptoms of discomfort or problems during the postpartum period and their relationship with the mode of delivery...

  • Article
  • Open Access
8 Citations
6,785 Views
8 Pages

Risk Factors for Perineal Wound Breakdown in Early Postpartum: A Retrospective Case–Control Study

  • Amandine Puissegur,
  • Marie Accoceberry,
  • Marion Rouzaire,
  • Bruno Pereira,
  • Marie Herault,
  • Clément Bruhat,
  • Amélie Delabaere and
  • Denis Gallot

21 April 2023

We conducted a retrospective case–control study in patients presenting a perineal tear (second degree or higher) or episiotomy complicated by wound breakdown during maternity stay to identify risk factors associated with wound breakdown in earl...

  • Article
  • Open Access
18 Citations
5,825 Views
9 Pages

Risk Factors in Third and Fourth Degree Perineal Tears in Women in a Tertiary Centre: An Observational Ambispective Cohort Study

  • Juan A. Barca,
  • Coral Bravo,
  • Maria P. Pintado-Recarte,
  • Ignacio Cueto-Hernández,
  • Javier Ruiz-Labarta,
  • Yolanda Cuñarro,
  • Julia Buján,
  • Melchor Alvarez-Mon,
  • Miguel A. Ortega and
  • Juan A. De León-Luis

21 July 2021

Objectives: To analyze the main risk factors associated with third and fourth degree postpartum perineal tears in women attended to in our obstetrics service. Methods: An observational, retrospective, hospital cohort study was carried out in women wh...

  • Article
  • Open Access
5 Citations
3,326 Views
14 Pages

Investigating the Effects of Different Sizes of Silicone Rubber Vacuum Extractors during the Course of Delivery on the Fetal Head: A Finite Element Analysis Study

  • Chuang-Yen Huang,
  • Kuo-Min Su,
  • Hsueh-Hsing Pan,
  • Fung-Wei Chang,
  • Yu-Ju Lai,
  • Hung-Chih Chang,
  • Yu-Chi Chen,
  • Chi-Kang Lin and
  • Kuo-Chih Su

14 February 2022

During certain clinical situations, some parturients require instruments for operative vaginal delivery, and various designs of vacuum extractors may affect the fetal head. To investigate the biomechanical effects of divergent sizes of silicone rubbe...

  • Review
  • Open Access
24 Citations
5,879 Views
29 Pages

Insights into Infusion-Based Targeted Drug Delivery in the Brain: Perspectives, Challenges and Opportunities

  • Asad Jamal,
  • Tian Yuan,
  • Stefano Galvan,
  • Antonella Castellano,
  • Marco Riva,
  • Riccardo Secoli,
  • Andrea Falini,
  • Lorenzo Bello,
  • Ferdinando Rodriguez y Baena and
  • Daniele Dini

Targeted drug delivery in the brain is instrumental in the treatment of lethal brain diseases, such as glioblastoma multiforme, the most aggressive primary central nervous system tumour in adults. Infusion-based drug delivery techniques, which direct...

  • Letter
  • Open Access
25 Citations
4,914 Views
8 Pages

In-Flight Calibration and Performance of the OSIRIS-REx Visible and IR Spectrometer (OVIRS)

  • Amy A. Simon,
  • Dennis C. Reuter,
  • Nicolas Gorius,
  • Allen Lunsford,
  • Richard G. Cosentino,
  • Galina Wind,
  • Dante S. Lauretta and
  • The OSIRIS-REx Team

18 September 2018

Performance of the Origins, Spectral Interpretation, Resource Identification, Security–Regolith Explorer (OSIRIS-REx) Visible and InfraRed Spectrometer (OVIRS) instrument was validated, showing that it met all science requirements during extensive th...

  • Review
  • Open Access
28 Citations
8,888 Views
20 Pages

Liposome-based drug delivery systems have revolutionized modern pharmaceutics, offering unparalleled versatility and precision in therapeutic delivery. These lipid vesicles, capable of encapsulating hydrophilic, hydrophobic, and amphiphilic drugs, ha...

  • Review
  • Open Access
25 Citations
8,661 Views
20 Pages

piggyBac-Based Non-Viral In Vivo Gene Delivery Useful for Production of Genetically Modified Animals and Organs

  • Masahiro Sato,
  • Emi Inada,
  • Issei Saitoh,
  • Satoshi Watanabe and
  • Shingo Nakamura

In vivo gene delivery involves direct injection of nucleic acids (NAs) into tissues, organs, or tail-veins. It has been recognized as a useful tool for evaluating the function of a gene of interest (GOI), creating models for human disease and basic r...

  • Article
  • Open Access
1 Citations
1,873 Views
9 Pages

22 January 2024

Microcrystal delivery instruments are pivotal to performing serial femtosecond crystallography experiments at the XFEL facilities. We present a novel sample delivery technique based on a micro-tubing reeling system (MRS). Despite the tiny size of the...

  • Article
  • Open Access
1,677 Views
13 Pages

Validation of the Wijma Delivery Expectancy/Experience Questionnaire (Version B) Among Greek Postpartum Women

  • Pinelopi Varela,
  • Ioannis Zervas,
  • Christina Nanou,
  • Victoria Vivilaki,
  • Aikaterini Lykeridou and
  • Anna Deltsidou

Background/Objectives: Postnatal fear of childbirth (FOC) has a significant impact on women’s mental health following childbirth. A widely employed tool for evaluating postnatal FOC is the Wijma Delivery Expectancy/Experience Questionnaire vers...

  • Article
  • Open Access
75 Views
16 Pages

Higher education institutions commonly employ student evaluation of teaching (SET) instruments (e.g., course evaluation surveys) to enhance course quality and inform instructional strategies. However, conceptualizing and measuring SET as a unidimensi...

  • Article
  • Open Access
24 Citations
4,653 Views
17 Pages

Facing the aggravating trend of an aging population and a fragmented medical service delivery system, the Chinese Central Government has introduced a series of policies to promote the development of integrated care against the background of the &ldqu...

  • Article
  • Open Access
13 Citations
4,288 Views
11 Pages

Effect of Siblings and Type of Delivery on the Development of Motor Skills in the First 48 Months of Life

  • Miguel Rebelo,
  • João Serrano,
  • Pedro Duarte-Mendes,
  • Rui Paulo and
  • Daniel A. Marinho

This study aimed to verify whether the presence of siblings and the type of delivery had an influence on the motor skills development of children in the first 48 months of life. We developed a quantitative study with a sample of 405 children of both...

  • Article
  • Open Access
8 Citations
2,957 Views
11 Pages

A Critical Evaluation of the Undergraduate Endodontic Teaching in Dental Colleges of Saudi Arabia

  • Mohammed A. Alobaid,
  • Saeed Awod Bin Hassan,
  • Ali H. Alfarhan,
  • Salma Ali,
  • Mohammad Shahul Hameed and
  • Sadatullah Syed

Background: The purpose of the research was to evaluate the content and delivery of the undergraduate endodontic curriculum. Methods: A needs assessment survey was distributed among the Deans of all the dental colleges in Saudi Arabia. Results: The r...

  • Article
  • Open Access
4 Citations
3,641 Views
17 Pages

Analysis of Provincial Policies on the Development of Prefabricated Construction in China

  • Kangkang Yan,
  • Huer Shuang,
  • Yongtao Tan,
  • Shuang Xiang and
  • Xiaolong Gan

Currently, China has launched an ambitious governmental initiative to promote the development of prefabricated construction (PC). As the target of PC development has been allocated to lower-level government, the responsibility for PC development rest...

  • Brief Report
  • Open Access
2 Citations
3,224 Views
8 Pages

Impact of Thin Meconium on Delivery and Early Neonatal Outcomes

  • Hanoch Schreiber,
  • Adi Shilony,
  • Reut Batia Amrami,
  • Gal Cohen,
  • Ofer Markovitch,
  • Tal Biron-Shental,
  • Sofia Bauer-Rusek,
  • Shmuel Arnon and
  • Michal Kovo

26 January 2023

Several reports regarding the effects of thin meconium on maternal and neonatal outcomes are contradictory. This study evaluated the risk factors and obstetrical outcomes during deliveries complicated with thin meconium. This retrospective cohort stu...

  • Article
  • Open Access
1 Citations
2,408 Views
20 Pages

Developing policy instruments related to urban freight, such as congestion pricing, urban consolidation schemes, and off-hours delivery, requires an understanding of the distribution of shipment delivery times. Furthermore, agent-based urban freight...

  • Review
  • Open Access
37 Citations
6,620 Views
23 Pages

Gold Nanoparticles for Vectorization of Nucleic Acids for Cancer Therapeutics

  • Daniela Ferreira,
  • David Fontinha,
  • Catarina Martins,
  • David Pires,
  • Alexandra R. Fernandes and
  • Pedro V. Baptista

31 July 2020

Cancer remains a complex medical challenge and one of the leading causes of death worldwide. Nanomedicines have been proposed as innovative platforms to tackle these complex diseases, where the combination of several treatment strategies might enhanc...

  • Article
  • Open Access
2 Citations
1,936 Views
6 Pages

Substantial Obstetric Anal Sphincter Injury during Vacuum Assisted Delivery: An Obstetrical Issue or Device Related?

  • Yoav Baruch,
  • Ronen Gold,
  • Hagit Eisenberg,
  • Hadar Amir,
  • Yariv Yogev and
  • Asnat Groutz

26 November 2022

Background: Obstetric anal sphincter injuries (OASIS) might be associated with long-term urinary and anorectal morbidities. The aim of the study was to investigate the risk factors and clinical implications of OASIS associated with vacuum-assisted de...

  • Article
  • Open Access
2 Citations
1,944 Views
14 Pages

Risk Factors for Anal Continence Impairment Following a Second Delivery after a First Traumatic Delivery: A Prospective Cohort Study

  • Gabriel Marcellier,
  • Axelle Dupont,
  • Agnes Bourgeois-Moine,
  • Arnaud Le Tohic,
  • Celine De Carne-Carnavalet,
  • Olivier Poujade,
  • Guillaume Girard,
  • Amélie Benbara,
  • Laurent Mandelbrot and
  • Laurent Abramowitz

15 February 2023

Postpartum anal incontinence is common. After a first delivery (D1) with perineal trauma, follow-up is advised to reduce the risk of anal incontinence. Endoanal sonography (EAS) may be considered to evaluate the sphincter and in case of sphincter les...

  • Feature Paper
  • Article
  • Open Access
15 Citations
4,477 Views
11 Pages

Single-Shot Coherent X-ray Imaging Instrument at PAL-XFEL

  • Daeho Sung,
  • Daewoong Nam,
  • Myong-jin Kim,
  • Seonghan Kim,
  • Kyung Sook Kim,
  • Sang-Youn Park,
  • Sun Min Hwang,
  • Chulho Jung,
  • Heemin Lee and
  • Do Hyung Cho
  • + 5 authors

30 May 2021

We developed a single-shot coherent X-ray imaging instrument at the hard X-ray beamline of the Pohang Accelerator Laboratory X-ray Free Electron Laser (PAL-XFEL). This experimental platform was established to conduct a variety of XFEL experiments, in...

  • Article
  • Open Access
8 Citations
2,285 Views
13 Pages

Upgraded Combined Inject-and-Transfer System for Serial Femtosecond Crystallography

  • Keondo Lee,
  • Donghyeon Lee,
  • Jaehyun Park,
  • Jong-Lam Lee,
  • Wan Kyun Chung,
  • Yunje Cho and
  • Ki Hyun Nam

11 September 2022

Serial femtosecond crystallography (SFX) using an X-ray free-electron laser (XFEL) can be applied to determine the room-temperature structure of target molecules while minimizing radiation damage and visualizing molecular dynamics. In SFX, a sample d...

  • Article
  • Open Access
4 Citations
4,995 Views
16 Pages

A Meta-Analysis of Comparing Intermittent Epidural Boluses and Continuous Epidural Infusion for Labor Analgesia

  • I-Shiang Tzeng,
  • Ming-Chang Kao,
  • Po-Ting Pan,
  • Chu-Ting Chen,
  • Han-Yu Lin,
  • Po-Chun Hsieh,
  • Chan-Yen Kuo,
  • Tsung-Han Hsieh,
  • Woon-Man Kung and
  • Chu-Hsuan Cheng
  • + 1 author

With the development of medical equipment and techniques in labor anesthesia, it is a major issue to investigate the risks and treatment effects among techniques such as continuous epidural infusion (CEI) and intermittent epidural bolus (IEB). Howeve...

  • Article
  • Open Access
1 Citations
2,710 Views
19 Pages

Enhanced Channel Calibration for the Image Sensor of the TuMag Instrument

  • Eduardo Magdaleno,
  • Manuel Rodríguez Valido,
  • David Hernández,
  • María Balaguer,
  • Basilio Ruiz Cobo,
  • David Orozco Suárez,
  • Daniel Álvarez García and
  • Argelio Mauro González

8 March 2022

The Sunrise missions consist of observing the magnetic field of the sun continuously for a few days from the stratosphere. In these missions, a balloon supporting a telescope and associated instrumentation, including a Tunable Magnetograph (TuMag), i...

  • Article
  • Open Access
3 Citations
3,523 Views
9 Pages

Consumption of Food Offered by Delivery Applications (Apps)

  • Jamile Carvalho Tahim,
  • Sara Maria Moreira Lima Verde,
  • Carla Soraya Costa Maia and
  • Ilana Nogueira Bezerra

This study aimed to investigate whether the use of food delivery applications is related to food consumption practices. Methods: Data collection was carried out between 5 and 20 June 2020 in a Brazilian capital with a final sample of 2113 individuals...

  • Article
  • Open Access
14 Citations
6,115 Views
16 Pages

Background: This article identifies the preferences of the customer of logistics services in Indonesia using the Kansei engineering and conjoint analysis methods. The Conjoint Analysis aims to establish utility scores that represent factors in logist...

  • Article
  • Open Access
1 Citations
1,192 Views
19 Pages

14 March 2025

Drone delivery services have attracted increasing interest in the retail business market. Drone delivery services have both positive and negative aspects considering privacy risk and eco-friendliness. Given these points, this work investigates the re...

  • Article
  • Open Access
1 Citations
6,786 Views
16 Pages

Integrating Genetic Services in the Philippine Public Health Delivery System: The Value of Networks

  • Carmencita D. Padilla,
  • Michelle E. Abadingo,
  • Ebner Bon G. Maceda and
  • Maria Melanie Liberty B. Alcausin

13 June 2024

The delivery of genetic services in developing countries is faced with significant challenges, despite medical and technological advances globally. The Philippines, being an archipelago, faces even more challenges, with significant disparities in acc...

  • Article
  • Open Access
10 Citations
3,164 Views
13 Pages

Serial femtosecond crystallography (SFX) using an X-ray free electron laser (XFEL) enables the determination of room-temperature structures without causing radiation damage. Using an optical pump-probe or mix-and-injection, SFX enables the intermedia...

  • Article
  • Open Access
1 Citations
5,189 Views
13 Pages

Mode of Delivery in Greece: A Study of Obstetricians’ Personal Preferences Regarding Delivery of Their Offspring

  • Panagiotis Christopoulos,
  • Ermioni Tsarna,
  • Anna Eleftheriades,
  • Ilias Korompokis,
  • Grigorios Karampas and
  • Nikos F. Vlachos

3 April 2025

Background: In Greece, the cesarean section (CS) rate reached 62.15% in 2023. This study aims to document Greek obstetricians’ preferences and choices regarding the delivery mode of their own children. Methods: A questionnaire was emailed to Gr...

  • Article
  • Open Access
13 Citations
7,777 Views
19 Pages

26 July 2022

Sustainable consumption and production (SCP) is largely influenced by dynamics in the market system. Hence, this study adopts the systems thinking approach as a tool to understand the non-linearity and complexity of sustainable practices. The food de...

  • Review
  • Open Access
18 Citations
6,573 Views
27 Pages

Microneedles and Their Application in Transdermal Delivery of Antihypertensive Drugs—A Review

  • Ramsha Khalid,
  • Syed Mahmood,
  • Zarif Mohamed Sofian,
  • Ayah R. Hilles,
  • Najihah Mohd Hashim and
  • Yi Ge

One of the most cutting-edge, effective, and least invasive pharmaceutical innovations is the utilization of microneedles (MNs) for drug delivery, patient monitoring, diagnostics, medicine or vaccine delivery, and other medical procedures (e.g., intr...

  • Article
  • Open Access
9 Citations
3,531 Views
10 Pages

Quantification of Unknown Nanoscale Biomolecules Using the Average-Weight-Difference Method

  • Kyungwoo Lee,
  • Yonghyun Choi,
  • Kyobum Kim,
  • Hyung-Jun Koo and
  • Jonghoon Choi

2 January 2019

In order to quantify the amount of drug molecules in drug delivery systems, analytical techniques such as high-performance liquid chromatography are used due to their accuracy and reliability. However, the instruments required for such techniques are...

  • Article
  • Open Access
14 Citations
8,315 Views
14 Pages

8 March 2022

The aim of the study is to identify legal instruments, implemented in France, supporting short food supply chains and, more generally, local food systems. The research has identified these tools from a variety of domains and levels, including nationa...

  • Article
  • Open Access
4 Citations
5,607 Views
11 Pages

New Aspects in the Formulation of Drugs Based on Three Case Studies

  • Patrick Frohberg,
  • Thi Nhat Phuong Nguyen and
  • Joachim Ulrich

The improvement of pharmaceutical dosage forms, such as tablets, towards drug delivery control and cost efficiency is of great importance in formulation technologies. Here, three examples: in situ coating, freeze casting and protein-based biocomposit...

  • Review
  • Open Access
13 Citations
3,801 Views
28 Pages

Smart Supra- and Macro-Molecular Tools for Biomedical Applications

  • Mariana Pinteala,
  • Marc J. M. Abadie and
  • Radu D. Rusu

27 July 2020

Stimuli-responsive, “smart” polymeric materials used in the biomedical field function in a bio-mimicking manner by providing a non-linear response to triggers coming from a physiological microenvironment or other external source. They are...

  • Article
  • Open Access
5 Citations
5,130 Views
12 Pages

The Impact of Delayed Symptomatic Treatment Implementation in the Intensive Care Unit

  • Lesley Meng,
  • Krzysztof Laudanski,
  • Mariana Restrepo,
  • Ann Huffenberger and
  • Christian Terwiesch

25 December 2021

We estimated the harm related to medication delivery delays across 12,474 medication administration instances in an intensive care unit using retrospective data in a large urban academic medical center between 2012 and 2015. We leveraged an instrumen...

  • Review
  • Open Access
38 Citations
5,160 Views
17 Pages

Development and Characterization of Nanoemulsions for Ophthalmic Applications: Role of Cationic Surfactants

  • Ana R. Fernandes,
  • Elena Sanchez-Lopez,
  • Tiago dos Santos,
  • Maria L. Garcia,
  • Amelia M. Silva and
  • Eliana B. Souto

8 December 2021

The eye is a very complex organ comprising several physiological and physical barriers that compromise drug absorption into deeper layers. Nanoemulsions are promising delivery systems to be used in ocular drug delivery due to their innumerous advanta...

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