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8 Results Found

  • Review
  • Open Access
2 Citations
4,003 Views
21 Pages

The Patho-Neurophysiological Basis and Treatment of Focal Laryngeal Dystonia: A Narrative Review and Two Case Reports Applying TMS over the Laryngeal Motor Cortex

  • Maja Rogić Vidaković,
  • Ivana Gunjača,
  • Josipa Bukić,
  • Vana Košta,
  • Joško Šoda,
  • Ivan Konstantinović,
  • Braco Bošković,
  • Irena Bilić and
  • Nikolina Režić Mužinić

15 June 2022

Focal laryngeal dystonia (LD) is a rare, idiopathic disease affecting the laryngeal musculature with an unknown cause and clinically presented as adductor LD or rarely as abductor LD. The most effective treatment options include the injection of botu...

  • Review
  • Open Access
8 Citations
8,523 Views
22 Pages

Botulinum Neurotoxin Therapy in the Clinical Management of Laryngeal Dystonia

  • Winnie Yeung,
  • Amanda L. Richards and
  • Daniel Novakovic

1 December 2022

Laryngeal dystonia (LD), or spasmodic dysphonia (SD), is a chronic, task-specific, focal movement disorder affecting the larynx. It interferes primarily with the essential functions of phonation and speech. LD affects patients’ ability to commu...

  • Review
  • Open Access
2 Citations
2,856 Views
13 Pages

Exploring Neurophysiological Mechanisms and Treatment Efficacies in Laryngeal Dystonia: A Transcranial Magnetic Stimulation Approach

  • Maja Rogić Vidaković,
  • Joško Šoda,
  • Joshua Elan Kuluva,
  • Braco Bošković,
  • Krešimir Dolić and
  • Ivana Gunjača

15 November 2023

Laryngeal dystonia (LD), known or termed as spasmodic dysphonia, is a rare movement disorder with an unknown cause affecting the intrinsic laryngeal muscles. Neurophysiological studies point to perturbed inhibitory processes, while conventional genet...

  • Article
  • Open Access
1 Citations
2,088 Views
14 Pages

Safety and Effectiveness of OnabotulinumtoxinA in Patients with Laryngeal Dystonia: Final Report of a 52-Week, Multicenter Postmarketing Surveillance Study

  • Shigeomi Iimura,
  • Yasuyo Nose,
  • Keiko Tabata,
  • Kenji Oda,
  • Yoshiyuki Yamashita,
  • Naohiro Takahashi and
  • Yoshiaki Kawano

5 September 2023

This postmarketing surveillance study was conducted to evaluate the safety and effectiveness of onabotulinumtoxinA in Japanese patients with laryngeal dystonia (LD). Patients receiving onabotulinumtoxinA for the first time were enrolled and observed...

  • Article
  • Open Access
1 Citations
2,335 Views
10 Pages

The Cortical Silent Period in the Cricothyroid Muscle as a Neurophysiologic Feature for Dystonia Observation: E-Field-Navigated Transcranial Magnetic (TMS) Study

  • Ivan Konstantinović,
  • Braco Bošković,
  • Joško Šoda,
  • Krešimir Dolić,
  • Zoran Đogaš,
  • Mirko Lapčić,
  • Vlatko Ledenko,
  • Toni Vrgoč and
  • Maja Rogić Vidaković

The cortical silent period (cSP) is a period of electrical silence following a motor-evoked potential (MEP) in the electromyographic signal recorded from a muscle. The MEP can be elicited by transcranial magnetic stimulation (TMS) over the primary mo...

  • Review
  • Open Access
5 Citations
5,362 Views
16 Pages

Central Autonomic Mechanisms Involved in the Control of Laryngeal Activity and Vocalization

  • Marta González-García,
  • Laura Carrillo-Franco,
  • Carmen Morales-Luque,
  • Marc Stefan Dawid-Milner and
  • Manuel Víctor López-González

13 February 2024

In humans, speech is a complex process that requires the coordinated involvement of various components of the phonatory system, which are monitored by the central nervous system. The larynx in particular plays a crucial role, as it enables the vocal...

  • Feature Paper
  • Review
  • Open Access
12 Citations
15,476 Views
16 Pages

Chemodenervation of the Larynx

  • Rachel Kaye and
  • Andrew Blitzer

2 November 2017

Botulinum neurotoxin (BoNT) has existed for thousands of years; however, it was not medically utilized until investigations into its therapeutic use began in sincerity during the late 1970s and 1980s. This, coupled with the reclassification of spasmo...

  • Article
  • Open Access
6 Citations
3,853 Views
14 Pages

Machine Learning Assessment of Spasmodic Dysphonia Based on Acoustical and Perceptual Parameters

  • Federico Calà,
  • Lorenzo Frassineti,
  • Claudia Manfredi,
  • Philippe Dejonckere,
  • Federica Messina,
  • Sergio Barbieri,
  • Lorenzo Pignataro and
  • Giovanna Cantarella

Adductor spasmodic dysphonia is a type of adult-onset focal dystonia characterized by involuntary spasms of laryngeal muscles. This paper applied machine learning techniques for the severity assessment of spasmodic dysphonia. To this aim, 7 perceptua...