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Characterization of DAG Binding to TRPC Channels by Target-Dependent cis–trans Isomerization of OptoDArG
- Hazel Erkan-Candag,
- Denis Krivic,
- Mathias A. F. Gsell,
- Mina Aleksanyan,
- Thomas Stockner,
- Rumiana Dimova,
- Oleksandra Tiapko and
- Klaus Groschner
Azobenzene-based photochromic lipids are valuable probes for the analysis of ion channel–lipid interactions. Rapid photoisomerization of these molecules enables the analysis of lipid gating kinetics and provides information on lipid sensing. Th...