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8 Results Found

  • Article
  • Open Access
17 Citations
4,523 Views
16 Pages

Preparation of Topical Itraconazole with Enhanced Skin/Nail Permeability and In Vivo Antifungal Efficacy against Superficial Mycosis

  • Laxman Subedi,
  • Seung-Yub Song,
  • Saurav Kumar Jha,
  • Sung-Ho Lee,
  • Rudra Pangeni,
  • Kyo-Tan Koo,
  • Beum Joon Kim,
  • Seung-Sik Cho and
  • Jin Woo Park

In this study, a stable and highly skin-permeable topical delivery system for itraconazole (ITZ) was designed to provide effective treatment against superficial mycosis. Herein, ITZ was incorporated into a solution composed of ethanol, benzyl alcohol...

  • Article
  • Open Access
1 Citations
2,536 Views
17 Pages

Evaluation of a Bioabsorbable Scaffold and Interlocked Nail System for Segmental Bone Defect

  • Morshed Khandaker,
  • Reuben Lane,
  • Shannon Yeakley,
  • Hussein Alizereej,
  • Sadegh Nikfarjam,
  • Abdellah Ait Moussa,
  • Melville B. Vaughan and
  • Amgad M. Haleem

In the current study, we designed and manufactured a scaffold and fixation system for the reconstruction of long-bone segmental defects in a rabbit tibia model. We used biocompatible and biodegradable materials, polycaprolactone (PCL) and PCL soaked...

  • Article
  • Open Access
8 Citations
4,097 Views
8 Pages

The Influence of Resin Infiltration Pretreatment on Orthodontic Bonding to Demineralized Human Enamel

  • Marina Simunovic Anicic,
  • Cecilia Goracci,
  • Jelena Juloski,
  • Ivana Miletic and
  • Senka Mestrovic

23 May 2020

Prior research reveal that low-viscosity resin is able to significantly penetrate initial caries lesions, which leads to their stabilization. The objective of the present report is to assess the shear bond strength (SBS) of orthodontic brackets bonde...

  • Review
  • Open Access
3 Citations
4,805 Views
16 Pages

A Narrative Review of the Evolution of Diagnostic Techniques and Treatment Strategies for Acral Lentiginous Melanoma

  • Myoung Eun Choi,
  • Eun Ji Choi,
  • Joon Min Jung,
  • Woo Jin Lee,
  • Yoon-Seo Jo and
  • Chong Hyun Won

27 September 2024

Acral melanoma (AM) is a subtype of cutaneous melanoma located on the palms, soles, and nails. The pathogenesis of AM involves mechanical stimulation and characteristic tumor-promoting mutations, such as those in the KIT proto-oncogene. Dermoscopy is...

  • Review
  • Open Access
2,901 Views
10 Pages

Physiopathological Aspects of Synovial Fluid and Membrane in Psoriatic Arthritis

  • Amelia Carmela Damasco,
  • Roberta Ramonda,
  • Giacomo Cozzi,
  • Mariagrazia Lorenzin,
  • Paolo Sfriso,
  • Francesca Oliviero and
  • Chiara Baggio

5 November 2024

Background: Psoriatic arthritis (PsA) is a chronic inflammatory arthropathy characterized by a variety of clinical manifestations, mainly affecting joints and entheses, but also skin, nails, the eye, and the intestine. Objectives: In this review, we...

  • Article
  • Open Access
6 Citations
4,202 Views
23 Pages

Weldability Evaluation of Alloy 718 Investment Castings with Different Si Contents and Thermal Stories and Hot Cracking Mechanism in Their Laser Beam Welds

  • Pedro Álvarez,
  • Alberto Cobos,
  • Lexuri Vázquez,
  • Noelia Ruiz,
  • Pedro Pablo Rodríguez,
  • Ana Magaña,
  • Andrea Niklas and
  • Fernando Santos

1 March 2021

In this work, weldability and hot cracking susceptibility of five alloy 718 investment castings in laser beam welding (LBW) were investigated. Influence of chemical composition, with varying Si contents from 0.05 to 0.17 wt %, solidification rate, an...

  • Article
  • Open Access
3 Citations
2,535 Views
11 Pages

An Injecting Molding Method for Forming the HFRP/PA6 Composite Parts

  • Bin Xu,
  • Meng-Yang Wei,
  • Xiao-Yu Wu,
  • Jian-Guo Lei,
  • Zhi-Wen Zhou,
  • Lian-Yu Fu and
  • Li-Kuan Zhu

23 November 2022

Carbon/glass fiber-reinforced polymer hybrid composite (HFRP) has the advantages of a light weight and high strength. For the lightweight design of automobile parts, composite parts made of HFRP and polymer materials are increasingly in demand. The m...

  • Review
  • Open Access
463 Views
23 Pages

Esophageal Lichen Planus—Contemporary Insights and Emerging Trends

  • Wolfgang Kreisel,
  • Rebecca Diehl,
  • Annegrit Decker,
  • Adhara Lazaro,
  • Franziska Schauer and
  • Annette Schmitt-Graeff

Background: Lichen planus (LP) is a common inflammatory disease affecting skin, mucous membranes, hairs, and nails, with an unpredictable course involving remissions and relapses. LP is a Type-I-Inflammation disease involving IFN-γ and IL-17 as...