Search Results (2,837)

Fine particulate matter (PM_2.5) exposure in public transport microenvironments has important implications for commuter health, yet concentration-based assessments may not adequately reflect the dose actually inhaled by passengers. This study quantified dynamic PM_2.5 inhaled doses in Taiyuan, China, using 1 Hz portable monitoring and matched travel surveys across 19 bus and metro routes during summer and winter 2025. After data screening, 1103 valid commuter samples were retained. We combined dose estimation with DML, XGBoost-SHAP, SEM, and Random Forest analysis to examine adjusted associations, explore potential nonlinear patterns, and characterize behavioral responses. Trip-averaged PM_2.5 concentrations exceeded the WHO 24 h guideline on most monitored routes when interpreted as a health-based reference benchmark for short commuting exposures rather than as a direct regulatory exceedance metric. More importantly, a clear concentration-dose decoupling pattern was observed: 6.6% of trips fell into a low-concentration but high-dose category, indicating that prolonged in-vehicle exposure could substantially elevate inhaled dose even when PM_2.5 concentrations remained below the sample median. The mean inhaled dose in the longer observed-duration group (top 20% by observed in-vehicle duration) reached 612.26 ± 412.21 μg, which was 7.2 times that of the remaining trips (84.87 ± 115.71 μg). DML results showed that inhaled dose, rather than PM_2.5 concentration alone, was significantly associated with psychological distress. SHAP analysis suggested an exploratory threshold-like pattern at approximately 300 μg per trip, above which health-risk attribution increased rapidly. SEM results indicated that inhaled dose was associated with higher self-reported somatic burden, whereas PM_2.5 concentration mainly influenced health indirectly through risk perception. These findings suggest that public transport exposure assessment should move beyond static concentration metrics and incorporate dynamic inhaled dose to better identify high-risk commuting scenarios and support more targeted health-oriented transit management. Full article

Background/Objectives: Insomnia is highly prevalent among patients with asthma and has been associated with systemic inflammation, reduced lung function, and increased mortality. This study investigated whether insomnia mediates the relationship between asthma control and psychosocial dysfunction, including social anhedonia and functional impairment. Methods: This cross-sectional study included 153 adults with physician-diagnosed asthma classified as controlled (n = 51) or uncontrolled (n = 102) according to the Asthma Control Test (ACT). Insomnia severity was assessed using the Athens Insomnia Scale (AIS), social anhedonia using the Revised Social Anhedonia Scale (RSAS), psychological distress using DASS-21, and functional impairment using the Functioning Assessment Short Test (FAST). Results: Uncontrolled asthma was associated with significantly higher insomnia severity and greater depression, anxiety, and stress levels (all p < 0.001). Asthma control emerged as the strongest independent predictor of insomnia severity (β = −0.451, p < 0.001). Although asthma control was not directly associated with social anhedonia or functional impairment, insomnia significantly mediated these relationships. The indirect effect of asthma control on social anhedonia via insomnia was significant (B = −0.1162, 95% CI [−0.2384, −0.0029]), as was the indirect effect on functional impairment (B = −0.4953, 95% CI [−0.8656, −0.1038]). Spirometric indices were not independently associated with psychosocial outcomes. Conclusions: Insomnia may represent an important intermediary process linking poor asthma control to psychosocial dysfunction. These findings highlight the clinical importance of assessing sleep disturbances in asthma patients and suggest that insomnia may contribute to broader psychosocial impairment beyond respiratory symptoms alone. Full article

Background and Objectives: This research aimed to compare Type D personality characteristics and self-esteem between individuals with chronic NSLBP and healthy controls, while also exploring their relationships with functional status, psychological symptoms, and quality of life within the patient group. Materials and Methods: In this cross-sectional investigation, 34 patients with chronic NSLBP were compared with 34 healthy controls with similar age and sex distribution. Pain intensity was quantified via the Visual Analog Scale (VAS), while functional impairment was evaluated using the Oswestry Disability Index (ODI). Psychological profiling included the Type D Scale-14 (DS14) for personality traits, the Rosenberg Self-Esteem Scale (RSES) for self-worth, and the Hospital Anxiety and Depression Scale (HADS) for emotional distress. Health-related quality of life was captured through the 12-Item Short Form Health Survey (SF-12). Results: Type D personality was significantly more prevalent in the NSLBP group than in controls (50% vs. 20.6%, p = 0.011). Patients with NSLBP had significantly higher negative affectivity (NA) scores (p < 0.001) and anxiety scores (p = 0.007) and lower SF-12 Physical Component Summary scores (p < 0.001) than controls. Pain intensity and disability were positively correlated with Type D personality traits, particularly NA and the Type D composite score. In exploratory subgroup analyses, patients with Type D personality also had higher pain intensity, disability, anxiety, and depression scores and lower SF-12 Mental Component Summary (MCS) scores than those without Type D personality. In adjusted regression analyses within the NSLBP group, Type D personality was associated with higher VAS (p = 0.004) and ODI scores (p = 0.007) and lower SF-12 MCS scores (p = 0.003). Conclusions: Type D personality characteristics were more frequent in patients with chronic NSLBP than in healthy controls and were associated with higher pain intensity, greater disability, higher anxiety and depressive symptom scores, and poorer mental quality-of-life scores within the patient group. In contrast, self-esteem did not differ significantly between patients and controls. Due to the inherent constraints of a cross-sectional framework and the potential construct redundancy between NA and emotional distress, the current results signify correlational links rather than definitive causality. Consequently, subsequent prospective research is vital to delineate the temporal dynamics and the long-term predictive value of Type D personality traits in the progression of chronic NSLBP. Full article

Background: Puberty is a period of visible bodily change, heightened self-consciousness, and increased sensitivity to social evaluation. While prior studies have linked pubertal development to broad psychological outcomes, less attention has been given to adolescents’ social evaluative distress, defined here as discomfort when feeling looked at or talked about by others. Parenting style may also be relevant to this outcome. Methods: Using secondary survey data from 3591 secondary-school students in Shenzhen, China, this study employed Bayesian analysis to examine whether puberty stress, authoritarian parenting, and permissive parenting were associated with adolescents’ social evaluative distress, and whether authoritarian and permissive parenting moderated the association between puberty stress and social evaluative distress. Results: Puberty stress was positively associated with social evaluative distress, and authoritarian parenting was also positively associated with this outcome. Permissive parenting did not show a clear direct association. Neither authoritarian nor permissive parenting showed clear evidence of moderating the association between puberty stress and social evaluative distress. Conclusions: Social evaluative distress during adolescence appears to be associated more clearly with puberty stress and authoritarian parenting as direct correlates than with interaction effects between puberty stress and parenting style. The study extends existing literature by focusing on a narrower, socially focused form of adolescent distress in the Chinese context. Full article

Background: Non-invasive respiratory supports (High-Flow Nasal Oxygen, HFNO; Continuous Positive Airway Pressure, CPAP; Non-Invasive Ventilation, NIV) are frequently used in Acute Hypoxemic Respiratory Failure (AHRF). However, the experience of assisted breathing may profoundly affect patients’ psychological balance, particularly during acute critical illness and subsequent rehabilitation. Aims and objectives: This longitudinal study investigated the psychological burden associated with non-invasive respiratory support use in patients with COVID-19-related AHRF, exploring changes in psychological functioning from acute hospitalization (RICU/ICU) (T0) to follow-up, conducted at a mean of 6.0 ± 3.1 months after respiratory rehabilitation (T1). Methods: Fifty-two patients (mean age = 66.9 ± 9.17 years) were assessed at T0 and T1. Standardized measures evaluated anxiety, psychological distress, post-traumatic stress symptoms, depression, and resilience, in relation to perceived illness severity and subjective experience of non-invasive respiratory support. Results: During acute care, patients reported high levels of fear and anxiety related to illness severity and uncertainty. The experience of non-invasive respiratory support, often perceived as a marker of critical condition, was associated with increased fear and anxiety (t(14) = 2.79, p = 0.014) compared to the recovery phase, leading to feelings of loss of control and diminished psychological well-being (t(17) = 2.35, p = 0.031). However, resilience significantly improved over time (t(16) = −4.78, p < 0.001). Conclusions: Non-invasive respiratory support may represent a psychologically demanding experience, often perceived as challenging to patients’ sense of safety and control. Encouragingly, psychological adaptation and resilience can improve during rehabilitation. Integrating structured psychological support within respiratory rehabilitation pathways may promote recovery and restore psychological balance in patients requiring assisted ventilation. Full article

Background: Workplace victimization is a form of repeated and systematic psychological violence that can severely affect both mental and physical health. From a psychological perspective, it impacts mood states, defense mechanisms, and personality functioning. Methods: This cross-sectional study investigated the psychological and behavioural correlates of workplace victimization in a sample of 33 workers from various professional sectors, using a multidimensional assessment including standardized measures of personality traits, mood states, and defense mechanisms. Results: The MMPI-2 profile revealed elevated scores in Hypochondriasis (Hs: 72.00), Depression (D: 70.21), Hysteria (Hy: 67.61), and Paranoia (Pa: 68.76), indicating somatic symptoms, depressive features, and suspiciousness. The POMS showed increased Tension–Anxiety (T: 65.06), Depression–Dejection (D: 68.21), Anger–Hostility (A: 68.15), and Fatigue–Inertia (F: 65.24), alongside reduced Vigor–Activity (V: 43.18). The DMI analysis highlighted a high Reversal score (REV: 65.91), suggesting a predominant use of defense mechanisms such as altruism and idealization to cope with distress. Conclusions: In this selected sample of adults referred for psychological evaluation for suspected or documented workplace victimization, participants showed a clinically relevant psychological burden, including depressive symptoms, somatic concerns, Anger–Hostility, fatigue, reduced vigor, and specific defensive patterns. Given the cross-sectional design, small sample size, and absence of a control group, these findings should be interpreted as preliminary and cannot establish causality or the specificity of this profile to workplace victimization. Full article

Background: The COVID-19 pandemic has generated widespread concerns regarding its long-term effects on children’s mental health. While numerous studies documented increased psychological distress among children during the pandemic, less is known about how children’s emotional and behavioral functioning have evolved in the post-pandemic period. Objective: This study examines patterns of children’s mental health using survey data collected in 2023 and 2025. Guided by the dual-factor model of mental health, the analysis considers both psychological difficulties and positive social functioning in order to provide a multidimensional understanding of children’s well-being. Method: Data were collected using the Strengths and Difficulties Questionnaire (SDQ-25), a widely used behavioral screening instrument assessing emotional symptoms, conduct problems, hyperactivity/inattention, peer relationship problems, and prosocial behavior. These domains were analyzed across two time points to explore patterns of change in internalizing difficulties, externalizing difficulties, and social strengths among school-age children in the post-pandemic context (N = 1262 students in 2023 and N = 575 students in 2025). Results: The findings suggest that children’s mental health after the pandemic reflects both persistent vulnerability and adaptive capacity. Emotional symptoms and behavioral challenges remain present among a proportion of children, indicating that the psychological effects of pandemic-related disruptions may extend beyond the immediate crisis period. At the same time, many children demonstrate relatively stable levels of prosocial behavior, highlighting the continued importance of positive social functioning as a protective factor for psychological adjustment. Contributions: These results underscore the importance of adopting a comprehensive perspective on children’s mental health that recognizes both difficulties and strengths. The study highlights the role of schools and families in supporting children’s post-pandemic recovery through early mental health screening, social–emotional learning initiatives, and programs that promote empathy and peer support. Such approaches may contribute to strengthening children’s resilience and long-term well-being in the aftermath of large-scale social disruptions. Full article

Introduction: Multiple Sclerosis (MS) is frequently associated with a range of neurological, cognitive and psychological issues, presenting significant challenges to patients’ Quality of Life (QoL). Among non-invasive neuromodulation techniques, transcutaneous spinal Direct Current Stimulation (tsDCS) is emerging as a potential approach for symptom management in neurological conditions. However, the effects of tsDCS on MS remain poorly explored. Thus, this preliminary study aimed to evaluate the effects of tsDCS on MS symptomatology, focusing on cognitive and psychological variables. Methods: Six patients with MS were recruited for a randomized, sham-controlled, double-blind crossover study, and received anodal tsDCS or sham stimulation in two separate sessions at least one month apart. Assessment outcomes included cognitive and attentional-executive functions, depressive symptoms, and several QoL components. The tests were administered at baseline (T0), immediately after treatment (T1), one week (T2) and one month (T3) post-treatment. Results: Although protocol-by-time interactions did not reach statistical significance across all measures, protocol-independent improvements over time were observed in various QoL subscales, including Physical Functioning, Role Limitations due to Physical Health, Vitality, Health Distress, and Overall QoL. Conclusions: Our findings indicate that tsDCS is a feasible and well-tolerated intervention in patients with MS, with possible implications for QoL. Given the small sample size and the exploratory nature of this study, further research is needed to clarify whether tsDCS may represent a potentially beneficial non-invasive neuromodulation approach for improving well-being in patients with MS across both physical and mental dimensions. Full article

Background/Objectives: The COVID-19 pandemic has raised concerns about maternal mental health, particularly among women infected during pregnancy. This study aimed to examine longitudinal changes in depressive and anxiety symptoms and subjective distress among pregnant women in Slovakia with confirmed SARS-CoV-2 infection and to explore the role of obstetric complications and vaccination status in these trajectories. Methods: In this retrospective longitudinal study, women with SARS-CoV-2 infection during pregnancy were assessed at three time points: during infection, six weeks postpartum, and one year postpartum (11 March 2020–5 May 2023). Depressive symptoms were measured using the Edinburgh Postnatal Depression Scale (EPDS; cut-off ≥ 11), anxiety symptoms were measured using the EPDS-3A subscale (cut-off ≥ 5), and subjective distress was measured using visual analogue scales (VAS). A repeated-measures ANCOVA design was used to evaluate within-subject changes over time while adjusting for vaccination status and pregnancy complications. Results: Of 1184 contacted women, 170 provided complete data. The proportion of women exceeding the EPDS cut-off decreased from 27.6% during infection to 17.6% at six weeks postpartum and 4.7% at one year postpartum. Anxiety symptoms showed a similar pattern, declining from 27.6% during infection to 20.6% at six weeks postpartum and 7.6% at one year postpartum. Repeated-measures analyses confirmed significant time effects across psychological outcomes, with symptom levels decreasing over the postpartum year. Post-infection obstetric complications were associated with higher subjective distress at selected time points. Conclusions: Psychological symptoms were highest during the acute infection period and declined significantly over time. These findings support the importance of timely mental health screening during pregnancy affected by COVID-19, while suggesting that, in many women, psychological distress may decrease across the postpartum year. Full article

Background/Objectives: Sleep disturbances are highly prevalent in young individuals with eating disorders (EDs) and are associated with increased psychopathology and poorer clinical outcomes. However, sleep alterations in ED populations are heterogeneous and may reflect distinct underlying clinical profiles. The study aimed to identify sleep quality profiles and examine their clinical correlates in youth with EDs. Methods: A total of 288 youth outpatients with EDs completed the Pittsburgh Sleep Quality Index (PSQI), along with measures of eating and general psychopathology. Latent Profile Analysis (LPA) was conducted using PSQI scores to identify distinct sleep profiles. Multinomial logistic regression models were performed to assess clinical variables of profile membership. Results: A four-profile solution was identified: (1) less impaired sleepers, (2) medication-using sleepers, (3) global poor sleepers, and (4) sleep-initiation-difficulty sleepers. Profiles differed significantly in ED severity, affective symptoms, emotion regulation difficulties, and sleep-related eating behaviors. Profiles characterized by greater sleep impairment exhibited higher levels of binge eating, night eating, and psychological distress. Multinomial logistic regression analyses indicated that night eating was the largest contributor to latent profile membership across all comparisons, significantly increasing the likelihood of belonging to more impaired sleep profiles. Conclusions: Sleep in individuals with EDs is characterized by distinct and clinically meaningful profiles rather than a uniform pattern of impairment. These findings support the clinical utility of person-centered approaches to better characterize sleep disturbances in ED populations. Full article

Background/Objectives: Ménière’s disease (MD) is a chronic inner-ear disorder characterized by vertigo, tinnitus, and fluctuating sensorineural hearing loss (SNHL) that impairs health-related quality of life (HRQoL) and is frequently accompanied by psychological distress. This study aims to quantify psychological distress and generic HRQoL in patients with definite MD compared with age- and sex-matched general-population controls and to examine the associations between hearing loss (HL) severity, symptom-related handicap, and these outcomes within the MD cohort. Methods: In this observational cross-sectional study, 45 adults with definite MD were recruited from an otolaryngology clinic in Portugal and individually matched (1:3) by sex and 10-year age strata to 135 participants from the EpiDoC population cohort. HRQoL was assessed using the SF-36v2 and EQ-5D-3L, psychological distress using the HADS, and tinnitus- and dizziness-related handicap using the THI and DHI. HL severity was staged using the AAO-HNS (1995) criteria. Results: Patients with MD had higher anxiety and depression scores and nearly twice the prevalence of abnormal anxiety compared with controls. SF-36v2 scores were significantly worse in several role and psychosocial domains, with less bodily pain but similar physical functioning and general health. EQ-5D-3L revealed a lower utility index and higher pain/discomfort and anxiety/depression. Within the MD cohort, HL stage was only weakly related to distress and HRQoL. In contrast, higher THI and DHI scores were consistently associated with more severe anxiety and depression and lower SF-36v2 scores. In multivariable analysis, abnormal anxiety was strongly associated with moderate-to-severe tinnitus handicap (OR = 17.5), whereas higher depressive symptoms independently predicted moderate-to-severe dizziness handicap, with abnormal anxiety showing a strong but borderline association with the latter. Conclusions: MD confers clinically meaningful HRQoL decrements and a higher psychological distress burden than in the general population. Tinnitus- and dizziness-related handicap and psychological distress, particularly anxiety, rather than HL severity, are key multidisciplinary management targets. Systematic screening for anxiety and depression, regardless of audiometric stage, should be integrated into MD care pathways. Full article

Background: Burnout is a relevant occupational health concern in Emergency Medical Services (EMSs), with potential implications for workforce well-being, occupational health, and the sustainability of prehospital care. Although burnout has been widely studied among healthcare professionals, evidence concerning Emergency Medical Technician (EMT) students remains limited. This exploratory study aimed to estimate high burnout prevalence among EMT students and practising EMT professionals in Madrid, Spain, describe burnout dimensions in both groups, and examine sociodemographic correlates of high burnout status. Methods: A cross-sectional comparative study was conducted between March and June 2024 using a convenience sample of 85 participants: 43 EMT students and 42 practising EMT professionals. Burnout was assessed using validated Spanish versions of the Maslach Burnout Inventory: the MBI-SS for students and the MBI-HSS for professionals. Because these instruments are population-specific and rely on different norms and thresholds, between-group comparisons of raw scores were interpreted as exploratory. Descriptive analyses, between-group comparisons with effect sizes, correlation analyses, and an exploratory binary logistic regression model were performed. Results: High burnout was identified in 22 EMT students (51.2%) and 23 practising EMT professionals (54.8%), with no statistically significant between-group difference detected (p = 0.73; Cramer’s V = 0.04). Between-group comparisons of burnout dimensions showed small effect sizes for Emotional Exhaustion (Cohen’s d = 0.17), Depersonalisation (Cohen’s d = 0.24), and Personal Accomplishment (Cohen’s d = −0.26). Age was positively associated with Emotional Exhaustion (r = 0.29, p = 0.008) and Depersonalisation (r = 0.24, p = 0.028), and negatively associated with Personal Accomplishment (r = −0.26, p = 0.019). In the exploratory adjusted logistic regression model, age was associated with high burnout status (OR = 1.05; 95% CI 1.01–1.10; p = 0.017), whereas group and sex were not significant correlates. Conclusions: High burnout levels were observed in both EMT students and practising EMT professionals in this regional exploratory sample. However, the findings should be interpreted cautiously due to the cross-sectional design, convenience sampling, modest sample size, limited statistical power, and use of population-specific burnout instruments. These results suggest that burnout-related distress may be relevant across the EMT training-to-practice pathway and support the need for larger longitudinal and multicentre studies incorporating occupational, educational, and organisational variables. Full article

This study examines the relationship between Sudanese audiences’ exposure to digital media coverage of the civil war and their psychological immunity and post-traumatic stress disorder (PTSD) symptoms while also investigating the mediating role of psychological immunity. Data were collected through an online survey from a sample of 774 Sudanese respondents residing both inside and outside Sudan. The findings indicate a relatively high level of exposure to digital news coverage, particularly through social media platforms such as Facebook, reflecting the growing centrality of digitally mediated news environments in conflict reporting. The results also reveal moderate levels of psychological immunity and relatively high levels of PTSD symptoms, especially in the hyperarousal dimension. Statistical analysis shows a negative association between media exposure and psychological immunity, and a positive association between exposure and PTSD symptoms, with psychological immunity partially mediating this relationship. Beyond these findings, this study highlights important implications for journalism practice and media responsibility. The intensity and emotional nature of digital war coverage raise critical concerns regarding ethical news production, the circulation of distressing content, and the potential psychological impact on audiences. These findings underscore the need for more responsible digital journalism practices, including content moderation, trauma-sensitive reporting, and the promotion of media literacy, in order to mitigate the potential harm associated with repeated exposure to crisis-related news content. Full article

Background: Insomnia symptoms associated with late chronotypes are prevalent among young adults, and frequently lead to sleep deprivation, morning-awakening difficulties, and excessive daytime sleepiness. These conditions are associated with psychological distress, impaired academic functioning, and reduced self-esteem. Although chronobiological behavioral interventions are effective, their accessibility remains limited. To bridge this gap, we developed a smartphone application delivering digital brief behavioral treatment for insomnia (BBT-I). We also designed a four-week program integrating the app with light therapy (LT) via wearable glasses named “Digital BBT-I + LT”. This randomized controlled trial will evaluate the efficacy of digital BBT-I with LT and digital BBT-I alone compared with a waitlist control group. Methods: This three-arm parallel-group randomized controlled trial will target young adults with insomnia symptoms and late chronotypes. Participants will be randomized to receive digital BBT-I with adjunctive LT, digital BBT-I alone, or a waitlist control condition. The primary outcome will be insomnia symptom severity, assessed using the Insomnia Severity Index. Evaluations will be conducted at baseline, weekly during the four-week intervention period (days 8, 15, 22, and 29), and at the 3-month follow-up. Discussion: Late chronotypes and insomnia significantly impair sleep and mental health in young adults. Despite the recognized importance of chronobiology-based treatments, they are rarely adopted as standard care. This highlights the need for scalable digital interventions, such as digital BBT-I. By rigorously assessing these strategies, this trial aims to provide clinical evidence regarding accessible interventions to improve sleep and mental health outcomes in this population. Full article

Background/Objectives: Non-celiac gluten sensitivity (NCGS) is a syndrome characterized by intestinal and extraintestinal symptoms triggered by gluten ingestion. Although anti-gliadin IgG antibody (AGA IgG) has been proposed as a potential biomarker for NCGS, its sensitivity and specificity in real-world clinical settings remain unclear. This study aimed to evaluate the clinical utility of AGA IgG in NCGS and to characterize its clinical features, including psychological distress and physical quality of life (QOL), in patients with clinically suspected NCGS attending a specialized outpatient unit in Japan, where patients reported symptoms related to the ingestion of gluten-containing grains (primarily wheat). Methods: We evaluated plasma AGA IgG levels in 45 patients with suspected NCGS based on clinical presentation and in 83 age- and sex-matched healthy controls. Plasma AGA IgG was measured using ELISA. Clinical symptoms and QOL were assessed using validated scales, including the 36-Item Short Form Health Survey (SF-36), Patient Health Questionnaire (PHQ-9 and PHQ-15), Generalized Anxiety Disorder-7 (GAD-7), and the Japanese version of the Irritable Bowel Syndrome Quality of Life measure (IBS-QOL-J). Results: The AGA IgG positivity rate was significantly higher in the suspected NCGS group (33.3%) than in the control group (13.3%; p < 0.01). Using clinical suspicion as the reference, the sensitivity and specificity of AGA IgG were 33.3% and 86.7%, respectively. Patients with suspected NCGS exhibited significantly lower physical and mental QOL and higher scores for depressive, anxiety, and somatic symptoms compared to controls. No significant clinical differences were found between AGA IgG-positive and IgG-negative individuals within the suspected NCGS group. Conclusions: AGA IgG demonstrated a specificity of 86.7% and a sensitivity of 33.3% for suspected NCGS, indicating its limited utility as a standalone biomarker. These findings suggest that suspected NCGS involves significant somatic and psychological burdens regardless of serological status. Future studies should explore whether a multi-marker panel could improve the identification of “True NCGS” in diverse clinical populations. Full article