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102 pages, 3538 KB  
Review
Mapping EEG Metrics to Human Affective and Cognitive Models: An Interdisciplinary Scoping Review from a Cognitive Neuroscience Perspective
by Evgenia Gkintoni and Constantinos Halkiopoulos
Biomimetics 2025, 10(11), 730; https://doi.org/10.3390/biomimetics10110730 (registering DOI) - 1 Nov 2025
Abstract
Background: Electroencephalography (EEG) offers millisecond-precision measurement of neural oscillations underlying human cognition and emotion. Despite extensive research, systematic frameworks mapping EEG metrics to psychological constructs remain fragmented. Objective: This interdisciplinary scoping review synthesizes current knowledge linking EEG signatures to affective and cognitive [...] Read more.
Background: Electroencephalography (EEG) offers millisecond-precision measurement of neural oscillations underlying human cognition and emotion. Despite extensive research, systematic frameworks mapping EEG metrics to psychological constructs remain fragmented. Objective: This interdisciplinary scoping review synthesizes current knowledge linking EEG signatures to affective and cognitive models from a neuroscience perspective. Methods: We examined empirical studies employing diverse EEG methodologies, from traditional spectral analysis to deep learning approaches, across laboratory and naturalistic settings. Results: Affective states manifest through distinct frequency-specific patterns: frontal alpha asymmetry (8–13 Hz) reliably indexes emotional valence with 75–85% classification accuracy, while arousal correlates with widespread beta/gamma power changes. Cognitive processes show characteristic signatures: frontal–midline theta (4–8 Hz) increases linearly with working memory load, alpha suppression marks attentional engagement, and theta/beta ratios provide robust cognitive load indices. Machine learning approaches achieve 85–98% accuracy for subject identification and 70–95% for state classification. However, significant challenges persist: spatial resolution remains limited (2–3 cm), inter-individual variability is substantial (alpha peak frequency: 7–14 Hz range), and overlapping signatures compromise diagnostic specificity across neuropsychiatric conditions. Evidence strongly supports integrated rather than segregated processing, with cross-frequency coupling mechanisms coordinating affective–cognitive interactions. Conclusions: While EEG-based assessment of mental states shows considerable promise for clinical diagnosis, brain–computer interfaces, and adaptive technologies, realizing this potential requires addressing technical limitations, standardizing methodologies, and establishing ethical frameworks for neural data privacy. Progress demands convergent approaches combining technological innovation with theoretical sophistication and ethical consideration. Full article
27 pages, 2119 KB  
Article
Analyzing Surface Spectral Signature Shifts in Fire-Affected Areas of Elko County Nevada
by Ibtihaj Ahmad and Haroon Stephen
Fire 2025, 8(11), 429; https://doi.org/10.3390/fire8110429 (registering DOI) - 31 Oct 2025
Abstract
This study investigates post-fire vegetation transitions and spectral responses in the Snowstorm Fire (2017) and South Sugarloaf Fire (2018) in Nevada using Landsat 8 Operational Land Imager (OLI) surface reflectance imagery and unsupervised ISODATA classification. By comparing pre-fire and post-fire conditions, we have [...] Read more.
This study investigates post-fire vegetation transitions and spectral responses in the Snowstorm Fire (2017) and South Sugarloaf Fire (2018) in Nevada using Landsat 8 Operational Land Imager (OLI) surface reflectance imagery and unsupervised ISODATA classification. By comparing pre-fire and post-fire conditions, we have assessed changes in vegetation composition, spectral signatures, and the emergence of novel land cover types. The results revealed widespread conversion of shrubland and conifer-dominated systems to herbaceous cover with significant reductions in near-infrared reflectance and elevated shortwave infrared responses, indicative of vegetation loss and surface alteration. In the South Sugarloaf Fire, three new spectral classes emerged post-fire, representing ash-dominated, charred, and sparsely vegetated conditions. A similar new class emerged in Snowstorm, highlighting the spatial heterogeneity of fire effects. Class stability analysis confirmed low persistence of shrub and conifer types, with grassland and herbaceous classes showing dominant post-fire expansion. The findings highlight the ecological consequences of high-severity fire in sagebrush ecosystems, including reduced resilience, increased invasion risk, and type conversion. Unsupervised classification and spectral signature analysis proved effective for capturing post-fire landscape change and can support more accurate, site-specific post-fire assessment and restoration planning. Full article
29 pages, 10037 KB  
Article
Assessing the Feasibility of Satellite-Based Machine Learning for Turbidity Estimation in the Dynamic Mersey Estuary (Case Study: River Mersey, UK)
by Deelaram Nangir, Manolia Andredaki and Iacopo Carnacina
Remote Sens. 2025, 17(21), 3617; https://doi.org/10.3390/rs17213617 (registering DOI) - 31 Oct 2025
Abstract
The monitoring of turbidity in estuarine environments is a challenging essential task for managing water quality and ecosystem health. This study focuses on the lower reaches of the River Mersey, Liverpool. Harmonized Sentinel-2 MSI Level-2A imagery was integrated with in situ measurements from [...] Read more.
The monitoring of turbidity in estuarine environments is a challenging essential task for managing water quality and ecosystem health. This study focuses on the lower reaches of the River Mersey, Liverpool. Harmonized Sentinel-2 MSI Level-2A imagery was integrated with in situ measurements from seven Environment Agency monitoring stations for two consecutive years (January 2023–January 2025). The workflow included image preprocessing, spectral index calculation, and the application of four machine learning algorithms: Gradient Boosting Regressor, XGBoost, Support Vector Regressor, and K-Nearest Neighbors. Among these, Gradient Boosting Regressor achieved the highest predictive accuracy (R2 = 0.84; RMSE = 15.0 FTU), demonstrating the suitability of ensemble tree-based methods for capturing non-linear interactions between spectral indices and water quality parameters. Residual analysis revealed systematic errors linked to tidal cycles, depth variation, and salinity-driven stratification, underscoring the limitations of purely data-driven approaches. The novelty of this study lies in demonstrating the feasibility and proof-of-concept of using machine learning to derive spatially explicit turbidity estimates under data-limited estuarine conditions. These results open opportunities for future integration with Computational Fluid Dynamics models to enhance temporal forecasting and physical realism in estuarine monitoring systems. The proposed methodology contributes to sustainable coastal management, pollution monitoring, and climate resilience, while offering a transferable framework for other estuaries worldwide. Full article
29 pages, 7616 KB  
Article
Dynamic Modeling and Analysis of Rotary Joints with Coupled Bearing Tilt-Misalignment Faults
by Jun Lu, Zixiang Zhu, Jie Ji, Yichao Yang, Xueyang Miao, Xiaoan Yan and Qinghua Liu
Entropy 2025, 27(11), 1123; https://doi.org/10.3390/e27111123 (registering DOI) - 31 Oct 2025
Abstract
This study systematically analyzes the dynamic behavior of bearing tilt-misalignment coupling faults in rotary joints and establishes a high-fidelity nonlinear dynamic model for a dual-support bearing–rotor system. By integrating Hertzian contact theory, the nonlinear contact forces induced by the tilt of the inner/outer [...] Read more.
This study systematically analyzes the dynamic behavior of bearing tilt-misalignment coupling faults in rotary joints and establishes a high-fidelity nonlinear dynamic model for a dual-support bearing–rotor system. By integrating Hertzian contact theory, the nonlinear contact forces induced by the tilt of the inner/outer rings and axial misalignment are considered, and expressions for bearing forces incorporating time-varying stiffness and radial clearance are derived. The system’s vibration response is solved using the Newmark-β numerical integration method. This study reveals the influence of tilt angle and misalignment magnitude on contact forces, vibration patterns, and fault characteristic frequencies, demonstrating that the system exhibits multi-frequency harmonic characteristics under misalignment conditions, with vibration amplitudes increasing nonlinearly with the degree of misalignment. Furthermore, dynamic models for single-point faults (inner/outer ring) and composite faults are constructed, and Gaussian filtering technology is employed to simulate defect surface roughness, analyzing the modulation effects of faults on spectral characteristics. Experimental validation confirms that the theoretical model effectively captures actual vibration features, providing a theoretical foundation for health monitoring and intelligent diagnosis of rotary joints. Full article
(This article belongs to the Special Issue Entropy-Based Fault Diagnosis: From Theory to Applications)
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24 pages, 7432 KB  
Article
Simulation of the Growth and Yield of Maize (Zea mays L.) on a Loosened Plinthosol Amended with Termite Mound Material in the Lubumbashi Region
by John Banza Mukalay, Joost Wellens, Jeroen Meersmans, Yannick Useni Sikuzani, Emery Kasongo Lenge Mukonzo and Gilles Colinet
Agriculture 2025, 15(21), 2272; https://doi.org/10.3390/agriculture15212272 (registering DOI) - 31 Oct 2025
Abstract
The low fertility of plinthosols is a major constraint on agricultural production, largely due to the presence of plinthite, which restricts the availability of water and nutrients. This study aimed to simulate the growth and yield of grain maize on a loosened plinthosol [...] Read more.
The low fertility of plinthosols is a major constraint on agricultural production, largely due to the presence of plinthite, which restricts the availability of water and nutrients. This study aimed to simulate the growth and yield of grain maize on a loosened plinthosol amended with termite mound (from Macrotermes falciger) material in the Lubumbashi region. A 660-hectare perimeter was established, subdivided into ten maize blocks (B1–B10) and a control block (B0), which received the same management practices as the other blocks except for subsoiling and termite mound amendment. The APSIM model was used for simulations. The leaf area index (LAI) was estimated from Sentinel-2 imagery via Google Earth Engine, using the Simple Ratio (SR) spectral index, and integrated into APSIM alongside agro-environmental variables. Model performance was assessed using cross-validation (2/3 calibration, 1/3 validation) based on the coefficient of determination (R2), Nash–Sutcliffe efficiency (NSE), and root mean square error (RMSE). Results revealed a temporal LAI dynamic consistent with maize phenology. Simulated LAI matched observations closely (R2 = 0.85 − 0.93; NSE = 0.50 − 0.77; RMSE = 0.29 − 0.40 m2 m−2). Maize grain yield was also well predicted (R2 = 0.91; NSE > 0.80; RMSE < 0.50 t ha−1). Simulated yields reproduced the observed contrast between treated and control blocks: 10.4 t ha−1 (B4, 2023–2024) versus 4.1 t ha−1 (B0). These findings highlight the usefulness of combining remote sensing and biophysical modeling to optimize soil management and improve crop productivity under limiting conditions. Full article
(This article belongs to the Section Agricultural Soils)
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16 pages, 2535 KB  
Article
Characterization and Discrimination of Pure Standards of Phenolic Compounds Using FTIR Spectroscopy in the Terahertz Range
by Audrey Pissard, Vincent Baeten, Quentin Arnould, Hervé Rogez and François Stevens
Foods 2025, 14(21), 3737; https://doi.org/10.3390/foods14213737 (registering DOI) - 31 Oct 2025
Viewed by 32
Abstract
Phenolic compounds (PCs) are bioactive molecules synthesized by plants and recognized for their antioxidant, antimicrobial, and anti-inflammatory properties. Traditional methods for their analysis, such as HPLC or GC, are time-consuming and costly, which motivates the exploration of faster and non-destructive alternatives. This study [...] Read more.
Phenolic compounds (PCs) are bioactive molecules synthesized by plants and recognized for their antioxidant, antimicrobial, and anti-inflammatory properties. Traditional methods for their analysis, such as HPLC or GC, are time-consuming and costly, which motivates the exploration of faster and non-destructive alternatives. This study investigates the potential of Fourier Transform Infrared (FTIR) spectroscopy in the Terahertz (THz) range for the identification and discrimination of PCs. Fifty-five pure standards, including phenolic acids and flavonoids, were analyzed using an FTIR spectrometer equipped with an Attenuated Total Reflectance (ATR) accessory. Measurements were performed at room temperature with 2–4 replicates. Repeatability and time reproducibility were good overall but decreased towards lower frequencies. Partial Least Squares Discriminant Analysis (PLS-DA) was applied as an exploratory tool to assess the global spectral variability among PCs and to determine whether their class or family was associated with systematic spectral features. The models achieved moderate to high accuracy in distinguishing between phenolic acids, flavonoids, and their subclasses. This study demonstrates the ability of THz spectroscopy to discriminate pure phenolic compounds despite their complex spectral profiles and represents a first step toward its application in real food products. Future work should address the limited sensitivity of FTIR spectroscopy for trace detection and the high absorption of water in the FIR–THz range, through experiments on dry mixtures of pure PCs and model food supplements to establish suitable conditions for food analysis. Full article
(This article belongs to the Section Food Analytical Methods)
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20 pages, 4788 KB  
Article
Vortex Dynamics Effects on the Development of a Confined Turbulent Wake
by Ioannis D. Kalogirou, Alexandros Romeos, Athanasios Giannadakis, Giouli Mihalakakou and Thrassos Panidis
Fluids 2025, 10(11), 283; https://doi.org/10.3390/fluids10110283 (registering DOI) - 31 Oct 2025
Viewed by 37
Abstract
In the present work, the turbulent wake of a circular cylinder in a confined flow environment at a blockage ratio of 14% is experimentally investigated in a wind tunnel consisting of a parallel test section followed by a constant-area distorting duct, under subcritical [...] Read more.
In the present work, the turbulent wake of a circular cylinder in a confined flow environment at a blockage ratio of 14% is experimentally investigated in a wind tunnel consisting of a parallel test section followed by a constant-area distorting duct, under subcritical Re inlet conditions. The initial stage of wake development, extending from the bluff body to the end of the parallel section, is analyzed, with the use of hot-wire anemometry and laser-sheet visualization. The near field reveals partial similarity to unbounded wakes, with the principal difference being a modification of the Kármán vortex street topology, attributed to altered vortex dynamics under confinement. Further downstream, the mean and fluctuating velocity distributions of the confined wake gradually evolve toward channel-flow characteristics. To elucidate this transition, wake measurements are systematically compared with channel flow data obtained in the same configuration under identical inlet conditions and with reference channel-flow datasets from the literature. Experimental results show that a vortex-transportation mechanism exists due to confinement effect, resulting in the progressive crossing and realignment of counter-rotating vortices toward the tunnel centerline. Although wake flow characteristics are preserved, suppression of classical periodic shedding is clearly depicted. Furthermore, it is shown that the confined near-wake spectral peak persists up to x1/d~60 as in the free case and then vanishes as the spectra broadens. Coincidentally, the confined wake exhibits a narrower halfwidth than its free wake counterpart, while a centerline shift of the shed vortices is observed. Farfield wake-flow maintains strong anisotropy, while a weaker downstream growth of the streamwise integral scale is observed when compared to channel flow. Together, these findings explain how confinement reforms the nearfield topology and reorganizes momentum transport as the flow evolves to channel-like flow. Full article
(This article belongs to the Special Issue Industrial CFD and Fluid Modelling in Engineering, 3rd Edition)
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14 pages, 3245 KB  
Article
Investigation of Structural Properties of n-Hexane and Decane under Different Cooling Regimes by Raman Spectroscopy
by Sokolov Dmitriy Yurievich, Tolynbekov Aidos Beibitbekuly, Korshikov Yevgeniy Sergeyevich, Filippov Vladimir Dmitrievich and Aldiyarov Abdurakhman Ualievich
Crystals 2025, 15(11), 938; https://doi.org/10.3390/cryst15110938 - 30 Oct 2025
Viewed by 82
Abstract
The glass-forming ability of short-chain alkanes remains a fundamental challenge in condensed matter physics. This study investigates the structural properties of n-hexane (C6H14) and decane (C10H22) under two distinct cooling regimes using Raman spectroscopy: fast [...] Read more.
The glass-forming ability of short-chain alkanes remains a fundamental challenge in condensed matter physics. This study investigates the structural properties of n-hexane (C6H14) and decane (C10H22) under two distinct cooling regimes using Raman spectroscopy: fast cooling (~50–100 K/s via contact freezing on a copper substrate at 77 K) and conventional cooling (~1–5 K/s). Despite employing rapid cooling protocols, both alkanes underwent crystallization without forming amorphous phases. n-Hexane formed a defective crystalline structure characterized by broad spectral bands (FWHM ~40–45 cm−1) and diffuse phase transitions in the 180–200 K range, while decane exhibited highly ordered crystalline structures with sharp spectral features (FWHM ~15–20 cm−1) and abrupt transitions at 220–240 K. Quantitative analysis of characteristic Raman bands (skeletal deformations, C-C stretching, and C-H stretching vibrations) revealed fundamental differences in crystallization mechanisms related to molecular chain length. The study demonstrates that contact freezing methods are fundamentally incapable of achieving the extreme cooling rates (>104 K/s) and ultra-thin film conditions (<1 μm) necessary for alkane vitrification. These findings establish spectroscopic diagnostic criteria for distinguishing between defective and well-ordered crystalline structures and define the limitations of conventional cryogenic techniques for glass formation in alkanes. Full article
(This article belongs to the Section Organic Crystalline Materials)
38 pages, 5789 KB  
Article
Rogue Wave Patterns for the Degenerate Three-Wave Resonant Interaction Equations: Spectral Jump and Deep Learning
by Hui-Min Yin, Gui Mu, Zhi-Qiang Yang and Kwok Wing Chow
Appl. Sci. 2025, 15(21), 11602; https://doi.org/10.3390/app152111602 - 30 Oct 2025
Viewed by 66
Abstract
Three-wave resonant interaction equations can model nonlinear dynamics in many fields, e.g., fluids, optics, and plasma. Rogue waves, i.e., modes algebraically localized in both space and time, are obtained analytically. The aim of this paper is to study degenerate three-wave resonant interaction equations, [...] Read more.
Three-wave resonant interaction equations can model nonlinear dynamics in many fields, e.g., fluids, optics, and plasma. Rogue waves, i.e., modes algebraically localized in both space and time, are obtained analytically. The aim of this paper is to study degenerate three-wave resonant interaction equations, where two out of the three interacting wave packets have identical group velocities. Physically, degenerate resonance typically occurs for dispersion relation, possessing many branches, e.g., internal waves in a continuously stratified fluid. Here, the Nth-order rogue wave solutions for this dynamical model are presented. Based on these solutions, we examine the effects of the group velocity on the width and structural profiles of the rogue waves. The width of the rogue waves exhibit a linear increase as the group velocity increases, a feature well-correlated with the prediction made using modulation instability. In terms of structural profiles, first-order rogue waves display ‘four-petal’ and ‘eye-shaped’ patterns. Second-order rogue waves can reveal intriguing configurations, e.g., ‘butterfly’ patterns and triplets. To ascertain the robustness of these modes, numerical simulations with random initial conditions were performed. Sequences of localized modes resembling these analytical rogue waves were observed. A spectral jump was observed, with the jump broadening in the case of rogue wave triplets. Furthermore, we predict new rogue waves based on information from two existing ones obtained using the deep learning technique in the context of rogue wave triplets. This predictive model holds potential applications in ocean engineering. Full article
(This article belongs to the Special Issue New Approaches for Nonlinear Waves)
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19 pages, 14128 KB  
Article
The Spectral Footprint of Neural Activity: How MUAP Properties and Spike Train Variability Shape sEMG
by Alvaro Costa-Garcia and Akihiko Murai
Bioengineering 2025, 12(11), 1181; https://doi.org/10.3390/bioengineering12111181 - 30 Oct 2025
Viewed by 153
Abstract
Surface electromyographic (sEMG) signals result from the interaction between motor unit action potentials (MUAPs) and neural spike trains, yet how specific features of spike timing shape the sEMG spectrum is not fully understood. Using a simplified convolutional model, we simulated sEMG by combining [...] Read more.
Surface electromyographic (sEMG) signals result from the interaction between motor unit action potentials (MUAPs) and neural spike trains, yet how specific features of spike timing shape the sEMG spectrum is not fully understood. Using a simplified convolutional model, we simulated sEMG by combining synthetic spike trains with MUAP templates, varying firing rate, temporal jitter, and motor unit synchronization to examine their effects on spectral characteristics. Rather than addressing a particular experimental condition such as fatigue or workload, the main goal of this study is to provide a framework that clarifies how variability in neural timing and muscle properties affects the observed sEMG spectrum. We introduce extractability indices to measure how clearly neural activity appears in the spectrum. Results show that MUAPs act as spectral filters, reducing components outside their bandwidth and limiting the detection of high firing rates. Temporal jitter spreads spectral energy and blunts frequency peaks, while moderate synchronization improves spectral visibility, partially countering jitter effects. These findings offer a reference for interpreting how neural and muscular factors shape sEMG signals, supporting a more informed use of spectral analysis in both experimental and applied neuromuscular studies. Full article
(This article belongs to the Section Biosignal Processing)
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20 pages, 1579 KB  
Article
Audio’s Impact on Deep Learning Models: A Comparative Study of EEG-Based Concentration Detection in VR Games
by Jesus GomezRomero-Borquez, Carolina Del-Valle-Soto, José A. Del-Puerto-Flores, Juan-Carlos López-Pimentel, Francisco R. Castillo-Soria, Roilhi F. Ibarra-Hernández and Leonardo Betancur Agudelo
Inventions 2025, 10(6), 97; https://doi.org/10.3390/inventions10060097 - 29 Oct 2025
Viewed by 171
Abstract
This study investigates the impact of audio feedback on cognitive performance during VR puzzle games using EEG analysis. Thirty participants played three different VR puzzle games under two conditions (with and without audio) while their brain activity was recorded. To analyze concentration levels [...] Read more.
This study investigates the impact of audio feedback on cognitive performance during VR puzzle games using EEG analysis. Thirty participants played three different VR puzzle games under two conditions (with and without audio) while their brain activity was recorded. To analyze concentration levels and neural engagement patterns, we employed spectral analysis combined with a preprocessing algorithm and an optimized Deep Neural Network (DNN) model. The proposed processing stage integrates feature normalization, automatic labeling based on Principal Component Analysis (PCA), and Gamma band feature extraction, transforming concentration detection into a supervised classification problem. Experimental validation was conducted under the two gaming conditions in order to evaluate the impact of multisensory stimulation on model performance. The results show that the proposed approach significantly outperforms traditional machine learning classifiers (SVM, LR) and baseline deep learning models (DNN, DGCNN), achieving a 97% accuracy in the audio scenario and 83% without audio. These findings confirm that auditory stimulation reinforces neural coherence and improves the discriminability of EEG patterns, while the proposed method maintains a robust performance under less stimulating conditions. Full article
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26 pages, 3341 KB  
Review
A Comprehensive Review of Rubber Contact Mechanics and Friction Theories
by Raffaele Stefanelli, Gabriele Fichera, Andrea Genovese, Guido Napolitano Dell’Annunziata, Aleksandr Sakhnevych, Francesco Timpone and Flavio Farroni
Appl. Sci. 2025, 15(21), 11558; https://doi.org/10.3390/app152111558 - 29 Oct 2025
Viewed by 160
Abstract
This review surveys theoretical frameworks developed to describe rubber contact and friction on rough surfaces, with a particular focus on tire–road interaction. It begins with classical continuum approaches, which provide valuable foundations but show limitations when applied to viscoelastic materials and multiscale roughness. [...] Read more.
This review surveys theoretical frameworks developed to describe rubber contact and friction on rough surfaces, with a particular focus on tire–road interaction. It begins with classical continuum approaches, which provide valuable foundations but show limitations when applied to viscoelastic materials and multiscale roughness. More recent formulations are then examined, including the Klüppel–Heinrich model, which couples fractal surface descriptions with viscoelastic dissipation, and Persson’s theory, which applies a statistical mechanics perspective and later integrates flash temperature effects. Grosch’s pioneering experimental work is also revisited as a key empirical reference linking friction, velocity, and temperature. A comparative discussion highlights the ability of these models to capture scale-dependent contact and energy dissipation while also noting practical challenges such as calibration requirements, parameter sensitivity, and computational costs. Persistent issues include the definition of cutoff criteria for roughness spectra, the treatment of adhesion under realistic operating conditions, and the translation of detailed power spectral density (PSD) data into usable inputs for predictive models. The review emphasizes progress in connecting material rheology, surface characterization, and operating conditions but also underscores the gap between theoretical predictions and real tire–road performance. Bridging this gap will require hybrid approaches that combine physics-based and data-driven methods, supported by advances in surface metrology, in situ friction measurements, and machine learning. Overall, the paper provides a critical synthesis of current models and outlines future directions toward more predictive and application-oriented tire–road friction modeling. Full article
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18 pages, 1819 KB  
Article
Speech Markers of Parkinson’s Disease: Phonological Features and Acoustic Measures
by Ratree Wayland, Rachel Meyer and Kevin Tang
Brain Sci. 2025, 15(11), 1162; https://doi.org/10.3390/brainsci15111162 - 29 Oct 2025
Viewed by 216
Abstract
Background/Objectives: Parkinson’s disease (PD) affects both articulatory and phonatory subsystems, leading to characteristic speech changes known as hypokinetic dysarthria. However, few studies have jointly analyzed these subsystems within the same participants using interpretable deep-learning-based measures. Methods: Speech data from the PC-GITA corpus, [...] Read more.
Background/Objectives: Parkinson’s disease (PD) affects both articulatory and phonatory subsystems, leading to characteristic speech changes known as hypokinetic dysarthria. However, few studies have jointly analyzed these subsystems within the same participants using interpretable deep-learning-based measures. Methods: Speech data from the PC-GITA corpus, including 50 Colombian Spanish speakers with PD and 50 age- and sex-matched healthy controls were analyzed. We combined phonological feature posteriors—probabilistic indices of articulatory constriction derived from the Phonet deep neural network—with harmonics-to-noise ratio (HNR) as a laryngeal measure. Linear mixed-effects models tested how these measures related to disease severity (UPDRS, UPDRS-speech, and Hoehn and Yahr), age, and sex. Results: PD participants showed significantly higher [continuant] posteriors, especially for dental stops, reflecting increased spirantization and articulatory weakening. In contrast, [sonorant] posteriors did not differ from controls, indicating reduced oral constriction without a shift toward more open, approximant-like articulations. HNR was predicted by vowel height and sex but did not distinguish PD from controls, likely reflecting ON-medication recordings. Conclusions: These findings demonstrate that deep-learning-derived articulatory features can capture early, subphonemic weakening in PD speech—particularly for coronal consonants—while single-parameter laryngeal indices such as HNR are less sensitive under medicated conditions. By linking spectral energy patterns to interpretable phonological categories, this approach provides a transparent framework for detecting subtle articulatory deficits and developing feature-level biomarkers of PD progression. Full article
(This article belongs to the Section Behavioral Neuroscience)
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14 pages, 916 KB  
Article
Limited Spectroscopy Data and Machine Learning for Detection of Zika Virus Infection in Aedes aegypti Mosquitoes
by Leonardo Reigoto, Rafael Maciel-de-Freitas, Maggy T. Sikulu-Lord, Gabriela A. Garcia, Gabriel Araujo and Amaro Lima
Trop. Med. Infect. Dis. 2025, 10(11), 308; https://doi.org/10.3390/tropicalmed10110308 - 29 Oct 2025
Viewed by 214
Abstract
This study presents a technique for categorizing Aedes aegypti mosquitoes infected with the Zika virus under laboratory conditions. Our approach involves the utilization of the near-infrared spectroscopy technique and machine learning algorithms. The model developed utilizes the absorption of light from 350 to [...] Read more.
This study presents a technique for categorizing Aedes aegypti mosquitoes infected with the Zika virus under laboratory conditions. Our approach involves the utilization of the near-infrared spectroscopy technique and machine learning algorithms. The model developed utilizes the absorption of light from 350 to 1000 nm. It integrates Linear Discriminant Analysis (LDA) of the signal’s windowed version to exploit non-linearities, along with Support Vector Machine (SVM) for classification purposes. Our proposed methodology can identify the presence of the Zika virus in intact mosquitoes with a balanced accuracy of 96% (row C2HT, average of columns TPR (%) and SPC (%)) when heads/thoraces of mosquitoes are scanned at 4, 7, and 10 days post virus infection. The model was 97.1% (10 DPI, row C2AB, column ACC (%)) accurate for mosquitoes that were used to test it, i.e., mosquitoes scanned 10-days post-infection and mosquitoes whose abdomens were scanned. Notable benefits include its cost-effectiveness and the capability for real-time predictions. This work also demonstrates the role played by different spectral wavelengths in predicting an infection in mosquitoes. Full article
(This article belongs to the Special Issue Beyond Borders—Tackling Neglected Tropical Viral Diseases)
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32 pages, 2334 KB  
Review
Recent Advances in SERS-Based Detection of Organophosphorus Pesticides in Food: A Critical and Comprehensive Review
by Kaiyi Zheng, Xianwen Shang, Zhou Qin, Yang Zhang, Jiyong Shi, Xiaobo Zou and Meng Zhang
Foods 2025, 14(21), 3683; https://doi.org/10.3390/foods14213683 - 29 Oct 2025
Viewed by 336
Abstract
Surface-enhanced Raman spectroscopy (SERS) has rapidly emerged as a powerful analytical technique for the sensitive and selective detection of organophosphorus pesticides (OPPs) in complex food matrices. This review summarizes recent advances in substrate engineering, emphasizing structure–performance relationships between nanomaterial design and molecular enhancement [...] Read more.
Surface-enhanced Raman spectroscopy (SERS) has rapidly emerged as a powerful analytical technique for the sensitive and selective detection of organophosphorus pesticides (OPPs) in complex food matrices. This review summarizes recent advances in substrate engineering, emphasizing structure–performance relationships between nanomaterial design and molecular enhancement mechanisms. Functional groups such as P=O, P=S, and aromatic rings are highlighted as key determinants of Raman activity through combined chemical and electromagnetic effects. State-of-the-art substrates, including noble metals, carbon-based materials, bimetallic hybrids, MOF-derived systems, and emerging liquid metals, are critically evaluated with respect to sensitivity, stability, and applicability in typical matrices such as fruit and vegetable surfaces, juices, grains, and agricultural waters. Reported performance commonly achieves sub-μg L−1 to low μg L−1 detection limits in liquids and 10−3 to 10 μg cm−2 on surfaces, with reproducibility often in the 5–15% RSD range under optimized conditions. Persistent challenges are also emphasized, including substrate variability, quantitative accuracy under matrix interference, and limited portability for real-world applications. Structure–response correlation models and data-driven strategies are discussed as tools to improve substrate predictability. Although AI and machine learning show promise for automated spectral interpretation and high-throughput screening, current applications remain primarily proof-of-concept rather than routine workflows. Future priorities include standardized fabrication protocols, portable detection systems, and computation-guided multidimensional designs to accelerate translation from laboratory research to practical deployment in food safety and environmental surveillance. Full article
(This article belongs to the Special Issue Non-Destructive Analysis for the Detection of Contaminants in Food)
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