1,792,605 Results Found

Background/Objectives: Awake procedures performed under spinal anesthesia (SA) have been associated with reduced hospitalization, costs, and postoperative complications compared with general anesthesia (GA). Endocan, an endothelial cell-specific prot...

Background/Objectives: The global syndemic of obesity, undernutrition, and climate change highlight the complex health and environmental challenges faced by young adults. These challenges may intensify during the transition to university. As a matter...

Background/Objectives: Silicosis, a fibrotic lung disease, is re-emerging globally, driven by an aggressive form linked to engineered stone processing that rapidly progresses to progressive massive fibrosis (PMF). The standard diagnostic approach, ch...

Background/Objectives: The advent of tyrosine kinase inhibitors (TKI), therapeutic antibodies and inducers of apoptosis has revolutionized cancer treatment, yet their application in pediatric tumors, particularly medulloblastoma, remains understudied...

Spider-derived venoms are a rich source of cystine knot peptides with immense therapeutic potential. Many of these peptides exert unique biological activities through the modulation of ion channels, including of human voltage-gated sodium (NaV1.1&nda...

This paper systematically analyzes the challenges of stabilizing tunnel excavations in zones with low overburden in urban environments, through an engineering-validated case study of the Kobilja Glava Tunnel. A combined approach involving the New Aus...

Fullerenols are polyhydroxylated derivatives of fullerene (C60(OH)n) with antioxidant, antiviral, and antibacterial properties and potential biomedical applications due to their solubility and biocompatibility. However, comprehensive assessment of th...

This study aimed to evaluate the effect of rosemary and oregano extracts on the chemical composition, physicochemical parameters, and sensory characteristics of pork pâtés under cold storage for 1, 7, and 14 days. Five different experime...

Background: Mitoxantrone (MX) is regularly used to treat several cancers. Despite its long history in the clinic, recent studies continue to unveil novel protein targets. These targets may contribute to the cytotoxic effects of the drug, as well as p...

Rapeseed pomace, a by-product of oil processing, is a rich source of bioactive compounds with potential antioxidant properties. This study aimed to evaluate the tocopherol content and antioxidant capacity of rapeseed pomace in comparison with commonl...

Urban disasters pose severe, concentrated risks to dense populations, generating asymmetric and time-critical demands on emergency services and infrastructure. To address these challenges, we develop a behaviorally informed shelter siting framework t...

Jinghe County, as a typical arid area unit in the Ebinur Lake Basin, has a fragile ecosystem background and prominent soil erosion problems which have posed a serious threat to regional ecological security. Therefore, this paper takes Jinghe County a...

Red blood cell (RBC) deformability is a critical biophysical property that enables effective passage of RBCs through microvasculature and ensures proper oxygen delivery. Impairment of this property is associated with various pathological conditions,...

Automatic speech recognition (ASR) technology faces the dual challenges of model complexity and noise robustness when deployed on terminal devices (e.g., mobile devices, embedded systems). To meet the demand for lightweight and high-performance model...

pH-responsive technology enables precise control over the release of functional molecules, thereby maximizing their bioavailability. As the first comprehensive assessment of pH-responsive systems within food science, this review systematically examin...

Background/Objectives: Tinnitus lateralization, a perceptual characteristic often neglected in clinical assessment, may reflect underlying auditory plasticity. This study aimed to investigate whether changes in tinnitus lateralization following a mul...

Alzheimer’s disease (AD), a neurodegenerative disorder of the aging brain, is associated with behavioral and cognitive issues and poses a huge burden on the global health care system. One of the key features of AD is the deposition of abnormal...

Background: Compassion fatigue (CF) is a state of emotional and physical exhaustion in the caregiving relationship, which can negatively impact patient safety and quality of care. Maternity care professionals are particularly vulnerable to CF due to...

Deeply buried carbonate successions in China’s Tarim Basin host substantial hydrocarbons. In the southern Tahe Oilfield, Middle–Lower Ordovician limestones show little evidence of subaerial weathering because the Upper Ordovician strata p...

Gastrodiae Rhizoma (GR) is known to have a medicinal and food-based homology. It is used to treat infantile convulsion, epilepsy, spasm, tetanus, and vertigo. In this study, an ultra-high performance liquid chromatography/tandem mass spectrometry (UH...

Chronic stress is a key risk factor for depression and metabolic dysfunction, widely mediated through oxidative stress and inflammatory pathways. Natural products such as honey are increasingly investigated for their potential to attenuate stress-ind...

The Lower Passaic River (LPR), located within the New York/New Jersey Harbor Estuarine System, has experienced long-term industrial activities, resulting in elevated concentrations of trace metals in sediment and water. This study aims to assess the...

The goal of decompilation is to convert compiled low-level code (e.g., assembly code) back into high-level programming languages, enabling analysis in scenarios where source code is unavailable. This task supports various reverse engineering applicat...

Habituation is a fundamental form of non-associative learning that allows organisms to filter out repetitive, non-salient stimuli but declines with age. While the kynurenine pathway (KP) of tryptophan metabolism is implicated in psychiatric and neuro...

Background: Cervical cancer is a public health concern, as a vast number of women are dying from it in Southern Africa [...]

Identifying the key drivers behind the spatiotemporal dynamics of ecosystem service functions is essential for clarifying how ecosystems respond to environmental changes. Such insights deepen our understanding of the evolution of complex ecological p...

An experimental and theoretical investigation of the reaction between chlorine atoms and propane/deuterated propane (C3H8/C3D8) was performed. The experimental work aimed to determine absolute and site-specific rate constants for hydrogen and deuteri...

Background: Both clinical and research data support the contribution of IL6-mediated local immunosuppression coupled with IL6-initiated protumorigenic processes, e.g., sustained proliferation and angiogenesis in the development of many cancers, inclu...

Background: Adolescent sleep problems are a public health concern, as roughly 60–70% of U.S. teens obtain less sleep than is recommended. Negative affect is a risk factor for adolescent sleep problems. However, factors explaining this associati...

The pathological loss of nuclear TDP-43 is a hallmark of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), leading to extensive alterations in RNA metabolism and a broad number of neuronal transcripts. However, the key effectors...

Accurate segmentation of navigable waters and obstacles is critical for unmanned surface vessel navigation yet remains challenging in real aquatic environments characterized by complex water textures and blurred boundaries. Current models often strug...

Rhizosphere hypoxia, caused by soil compaction and waterlogging, is a major constraint on agricultural productivity. It severely impairs crop growth and yield by inhibiting root aerobic respiration, disrupting energy metabolism, and altering the rhiz...

Background/Objectives: Shift work and chronotype influence timing and type of food consumed, yet their combined influence is unclear. This study determined differences between temporal patterns of eating (times of first (FEO), last (LEO), and largest...

Accurate prediction of drilling speed is essential in mechanical drilling operations, as it improves operational efficiency, enhances safety, and reduces overall costs. Traditional prediction methods, however, are often constrained by delayed respons...

Background/Objectives: Following the global spread of SARS-CoV-2, there was an urgent need for vaccine development to support immune protection. This study aimed to evaluate the impact of active and hybrid immunity on the durability of immunoglobulin...

Urban densification intensifies the heat island effect, threatening ecological security. Green spaces, as crucial spatial elements in regulating the urban thermal environment, remain poorly understood in terms of their morphological characteristics a...

Introduction: Choosing the optimal inhaler is crucial for effective management of asthma and COPD. Preferences and experiences may differ between patients and healthcare providers. The NEXThaler®, a dry powder inhaler (DPI), was developed to simp...

Background: Artificial intelligence (AI) has been proposed as a transformative tool in suicide prevention, yet most evidence remains observational. To provide a rigorous benchmark, we systematically reviewed randomized controlled trials (RCTs) evalua...

With the continuous increase in the proportion of wind and solar power, the strong randomness and volatility of distributed new energy output have brought great challenges to the planning, regulation, and operation of the new distribution system. Dis...

Deep tech is a broad concept encompassing scientifically and technologically advanced innovations, enterprises, and projects based on profound scientific and engineering knowledge. It addresses complex technological challenges while considering envir...

Background: Gastric cancer is a major global health burden. Although neoadjuvant chemotherapy and conversion surgery can improve survival, treatment responses vary owing to chemotherapy resistance. Cancer stem cells (CSCs), characterized by self-rene...

Severe combined immunodeficiency (SCID) and spinal muscular atrophy (SMA) are being added to the Newborn Bloodspot Screening (NBS) programme in the Republic of Ireland. To support this expansion, we conducted a scoping review to identify reported tim...

Amaranthus L. includes valuable and promising crops of multi-purpose use, having high morphological diversity and complicated taxonomy. Their karyotypes and genomic relationships remain insufficiently studied. For the first time, a comparative repeat...

The micronutrient content is a major aspect of food quality and has been under threat after a gain in production post-green revolution. Calcium (Ca) and magnesium (Mg) are the micronutrients that are cofactors for many enzymes and play a critical rol...

In recent years, the number of diabetes patients worldwide has been increasing daily, and more than 700 million people are in a prediabetic state. Fructus arctii exhibits notable anti-diabetic activity, but its active components remain unclear. In th...

Biplot methods provide a framework for the simultaneous graphical representation of both rows and columns of a data matrix. Classical biplots were originally developed for continuous data in conjunction with principal component analysis (PCA). In rec...

Background/Objectives: Pregnant women with Inflammatory Bowel Disease (IBD) require careful management to ensure optimal maternal and fetal outcomes. Whether IBD is a risk factor for pre-eclampsia is controversial. We aimed to investigate the inciden...

Bufadienolides exert broad-spectrum pharmacological activities relevant to cardiology and novel cancer treatments. Their efficacy, toxicity, and pharmacokinetic profiles are significantly affected by modifications at carbon-3 (C3) of the steroid core...

This study presents a practical framework for the maximal covering location problem (MCLP) under uncertainty. The approach combines possibility theory with chance-constrained programming to represent both imprecision and randomness in demand. Demand...

Autism spectrum disorder (ASD) is a neurodevelopmental condition mainly characterized by social impairments and repetitive behaviors. An altered intestinal barrier morphology and increased transmucosal leaks have also been implicated in ASD; in fact,...