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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genetic, Functional and Therapeutic Aspects of Procoagulant and Anticoagulant Factors 2.0
edited by and
submission deadline 31 May 2024 | 3 articles | Viewed by 3818 | Submission Open
Keywords: procoagulant factors; anticoagulant factors; hemostasis; inflammation; genetics; therapeutics; cell signaling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Interaction between Cell and Virus 2.0
edited by
submission deadline 31 May 2024 | 3 articles | Viewed by 3757 | Submission Open
Keywords: viral replication; gene expression; lytic infection; viral structure; viral assembly; cell signaling pathway; post-translational modification; immune evasion; viral tumorigenesis; antiviral medication
(This special issue belongs to the Section Molecular Microbiology)
In Honor of Elie Metchnikoff, a Nobel Prize Winner, Who Discovered Macrophages as Phagocyte Cells Involved in the Process of Innate Immunity
edited by
submission deadline 31 May 2024 | 3 articles | Viewed by 3541 | Submission Open
Keywords: macrophages; monocytes; phagocytes; fibroblast; cytokines; chronic disease; autoimmune disease; inflammatory disease; immune response; disease treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
New Sights: Genetic Advances and Challenges in Rare Diseases
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 3451 | Submission Open
Keywords: rare diseases; cavernomas; NGS; exome/genome; epigenome; undiagnosed rare diseases; phenotype– genotype correlations; transcription regulation; biomarkers; personalized medicine; precision medicine
(This special issue belongs to the Section Molecular Genetics and Genomics)
Mesenchymal Stem Cells and Cancer
edited by Krisztián Németh and Balazs Mayer
submission deadline 31 May 2024 | 2 articles | Viewed by 3359 | Submission Open
Keywords: cancer; microenvironment; tumor stroma; cancer-associated fibroblast; mesenchymal stem cell; cancer immunology; angiogenesis; metastasis; targeted cancer therapy; checkpoint inhibitor; CAR-T cells; immunotherapy; signal transduction; small molecules
(This special issue belongs to the Section Molecular Oncology)
Molecular Control of Metabolism and Growth Processes submission deadline 31 May 2024 | 3 articles | Viewed by 3347 | Submission Open
Keywords: metabolism; growth; micronutrients; feed additives; musculo-skeletal growth; orexigenic and anorexigenic signals; metabolic aging
(This special issue belongs to the Section Molecular Biology)
Molecular Advances in Platelets submission deadline 31 May 2024 | 1 articles | Viewed by 3273 | Submission Open
Keywords: platelets; immune thrombocytopenia; diagnosis; treatment; thrombopoietin; thrombopoietin receptor agonists; immunosuppression; eltrombopag; romiplostim; rituximab
(This special issue belongs to the Section Molecular Immunology)
New Advances in Mycoplasma Research
edited by
submission deadline 31 May 2024 | 2 articles | Viewed by 3255 | Submission Open
Keywords: mollicutes; mycoplasma; minimal cell; system biology; synthetic biology; omics; pathogenesis; host– pathogen interactions
(This special issue belongs to the Section Molecular Microbiology)
Genetic Engineering in Microbial Biotechnology submission deadline 31 May 2024 | 4 articles | Viewed by 3178 | Submission Open
Keywords: white biotechnology; red biotechnology; green biotechnology; yellow biotechnology; genetic engineering; microorganisms; bacteria; enzymes; genetics; bioproducts
(This special issue belongs to the Section Molecular Microbiology)
Glycobiology: The New Discoveries, Approaches, and Technical Developments
edited by Sanja Dabelić
submission deadline 31 May 2024 | 3 articles | Viewed by 3157 | Submission Open
Keywords: glycans; lectins; glycoconjugates; glycosylation; genetic disorders of glycosylation; glycomics and glycoproteomics
(This special issue belongs to the Section Macromolecules)
Dermatology: Advances on Pathophysiology and Therapies 2.0
edited by , Belén De la Hoz and
submission deadline 31 May 2024 | 2 articles | Viewed by 3101 | Submission Open
Keywords: immunodermatology; cutaneous lymphoma; cutaneous drug reaction; erythroderma; psoriasis; atopic dermatitis; eczematous reactions; cutaneous manifestation of systemic diseases; cutaneous vasculitis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Nanostructures: Preparation, Structural Characteristics and Properties
edited by
submission deadline 31 May 2024 | 2 articles | Viewed by 3070 | Submission Open
Keywords: nanostructures; synthesis methods; optical and electronic properties; morphology; band gap engineering; spectroscopy; photocatalysis; metal doping; nanoheterostructures; antioxidant and antimicrobial activity; biomedical applications
(This special issue belongs to the Section Molecular Nanoscience)
Plant Phylogenomics and Genetic Diversity 2.0
edited by
submission deadline 31 May 2024 | 3 articles | Viewed by 2986 | Submission Open
Keywords: plant phylogenomics; genome; gene evolution; species diversity; speciation; ecogenomics
(This special issue belongs to the Section Molecular Plant Sciences)
Editorial Board Members’ Collection Series: Nanomedicine in Cancer submission deadline 31 May 2024 | 1 articles | Viewed by 2976 | Submission Open
Keywords: cancer; nanomedicine; nanoparticles; hyperthermia; nanodrug delivery; nanotoxicity; nanodiagnostics
(This special issue belongs to the Section Molecular Oncology)
Functional Optical Nano/Micromaterials 2.0
edited by and Won Yeop Rho
submission deadline 31 May 2024 | 2 articles | Viewed by 2939 | Submission Open
Keywords: optical materials SERS (surface-enhanced Raman scattering); metal; nanoparticles; quantum dots; carbon materials; biomedicine sensing
(This special issue belongs to the Section Materials Science)
Novel Psychoactive Substances: Pharmacokinetics, Pharmacodynamics and Pharmaco-Toxicological Aspects
edited by and
submission deadline 31 May 2024 | 3 articles | Viewed by 2934 | Submission Open
Keywords: novel psychoactive substances; synthetic cannabinoids; synthetic cathinones; synthetic opioids; phenethylamines; forensic toxicology; new benzodiazepines; genetic and epigenetic toxicology; neuropsychopharmacology; new approach methodologies (NAMs)-based studies
(This special issue belongs to the Section Molecular Toxicology)
Proteins and Mutations: Inherited Diseases, Drug Resistance and Pharmacogenomics
edited by and Carlo R. Largiadèr
submission deadline 31 May 2024 | 2 articles | Viewed by 2845 | Submission Open
Keywords: allostery; cancer; drug metabolism; drug resistance; drug and vaccine development; infectious diseases; missense mutations; pathogenicity; pharmacogenomics; rare diseases
(This special issue belongs to the Section Biochemistry)
Research Advances in Emerging Infectious Diseases
edited by
submission deadline 31 May 2024 | 3 articles | Viewed by 2776 | Submission Open
Keywords: infectious diseases; immuene system; combination treament
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Transport of Nutrients and Ions Relevant to Human Pathophysiology
edited by and Tiziano Mazza
submission deadline 31 May 2024 | 3 articles | Viewed by 2742 | Submission Open
Keywords: membrane transporters; SLC; transport system; nutrient transport; ion transport; metabolism; human pathophysiology
(This special issue belongs to the Section Biochemistry)
Kynurenic Acid: Emerging Research Advances and Therapeutic Implications
edited by Piotr Paluszkiewicz and Monika Turska-Kozłowska
submission deadline 31 May 2024 | 3 articles | Viewed by 2738 | Submission Open
Keywords: kynurenic acid; kynurenine pathway; kynurenine; therapeutic use; supply and distribution
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular Mechanisms Regulating Central and Peripheral Immunity in Neurodegenerative Diseases submission deadline 31 May 2024 | 2 articles | Viewed by 2736 | Submission Open
Keywords: signalling pathways; transcriptional regulation; immune system; neurodegenerative diseases; receptors; neuroinflammation; cytokines
(This special issue belongs to the Section Molecular Immunology)
Advances in the Renin-Angiotensin System
edited by
submission deadline 31 May 2024 | 3 articles | Viewed by 2736 | Submission Open
Keywords: renin– angiotensin system (RAS); renin; angiotensin; angiotensin receptor; new therapeutic target; RAS and hypertension; RAS and cardiovascular diseases
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
The NLRP3-Inflammasome in Health and Disease 2.0
edited by
submission deadline 31 May 2024 | 2 articles | Viewed by 2697 | Submission Open
Keywords: NLRP3-inflammasome; mitochondrial dysfunction; oxidative stress; IL-1β – IL-18; genetic variants of NLRP3 inflammasome
(This special issue belongs to the Section Molecular Immunology)
Toxicity Mechanism of Emerging Pollutants submission deadline 31 May 2024 | 5 articles | Viewed by 2606 | Submission Open
Keywords: emerging pollutant; toxicology; cancer; EDC; pesticides; microplastic; human cell lines; environment; molecular mechanisms
(This special issue belongs to the Section Molecular Toxicology)
Molecular Mechanisms in Tumorigenesis of NMSC
edited by and Panagiotis Kouklis
submission deadline 31 May 2024 | 2 articles | Viewed by 2606 | Submission Open
Keywords: skin cancer; NMSC; tumorigenesis; genetics; biomarkers; biology; microenvironment; exosomes
(This special issue belongs to the Section Molecular Oncology)
Molecular and Cellular Mechanisms of Epilepsy 3.0
edited by
submission deadline 31 May 2024 | 2 articles | Viewed by 2506 | Submission Open
Keywords: epilepsy; epilepsy models; epileptogenesis; preventing epilepsy; neuroinflammation; neuroprotection; synaptic plasticity; neuron– astrocyte interaction
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Advances in Lung Diseases 2.0
edited by
submission deadline 31 May 2024 | 2 articles | Viewed by 2489 | Submission Open
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Advances in Luminescence: From Mechanisms to Applications submission deadline 31 May 2024 | 3 articles | Viewed by 2467 | Submission Open
Keywords: photoluminescence; halide perovskites; bioimaging; phonon-assisted upconversion; fluorescent sensors; photoluminescence microspectroscopy; luminescent nanothermometry; luminescence of biological tissues; color centers; quantum dots
(This special issue belongs to the Section Physical Chemistry and Chemical Physics)
Microanatomical and Molecular Updates on Brain Aging
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 2224 | Submission Open
Keywords: brain aging; brain structure; cryo-EM; confocal microscopy; cytokine; deconvolution; dementia; development; lightsheet imaging; neuroimmunity; proteinopathy; super-resolution imaging
(This special issue belongs to the Section Molecular Neurobiology)
Recent Molecular Advances in the Pathology and Therapeutics of Musculoskeletal Disease submission deadline 31 May 2024 | 2 articles | Viewed by 2212 | Submission Open
Keywords: osteoporosis; rheumatoid arthritis; bone metastasis; cytokines; immunopathology; immunotherapy; musculoskeletal
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Notch Signaling Pathways
edited by Marcia Bellon
submission deadline 31 May 2024 | 1 articles | Viewed by 2123 | Submission Open
Keywords: Notch signaling; Notch and the tumor microenvironment; Notch therapeutics; Notch neuronal aspects; Notch cardiac aspects; Notch immune aspects; Notch endocrine development processes; Notch and stem cells; Notch single cell analysis; Notch noncanonical signaling pathways; Notch as a tumor suppressor
(This special issue belongs to the Section Molecular Biology)
Applied and Translational Research on Bioactive Peptides and Proteins
edited by Paola Gagni
submission deadline 31 May 2024 | 2 articles | Viewed by 2053 | Submission Open
Keywords: bioactive proteins/peptides; applied/translational research; bioengineering; biosensors; biomarkers; biotechnology; biochemistry; nanotechnology; food industry
(This special issue belongs to the Section Molecular Biology)
Mechanism Research and Disease Assessment of Drug-Induced Liver Injury
edited by
submission deadline 31 May 2024 | 2 articles | Viewed by 2035 | Submission Open
Keywords: DILI; hepatotoxicity; DILI drugs; liver injury
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Novel Insight into Pulmonary Vascular Disease
edited by Charles E. Norton
submission deadline 31 May 2024 | 2 articles | Viewed by 1997 | Submission Open
Keywords: pulmonary hypertension; pulmonary fibrosis; hypoxia; smooth muscle cells; endothelial dysfunction; vasoconstriction; vascular remodeling
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Functional Nanomaterials: Structures, Compositions and Various Applications submission deadline 31 May 2024 | 2 articles | Viewed by 1937 | Submission Open
Keywords: functional materials; nanomaterials; nanostructures; nanoelectronics; molecular electronics; nanosensors; nanodevices; 2D materials; molecular magnetism
(This special issue belongs to the Section Molecular Nanoscience)
Immunity in Neurodegenerative Diseases: Systemic Immune Imbalance, Neuroinflammation, and Beyond
edited by and
submission deadline 31 May 2024 | 1 articles | Viewed by 1861 | Submission Open
Keywords: neurodegeneration; CNS immunosurveillance; neuroinflammation; neuro-immune axis; glia; T cells; phagocytosis; immunomodulation; autoimmunity; immunodeficiency
(This special issue belongs to the Section Molecular Neurobiology)
New Perspective in the Molecular Pathways Involved in Acute and Chronic Lung Injury
edited by
submission deadline 31 May 2024 | 2 articles | Viewed by 1835 | Submission Open
Keywords: acute lung injury; chronic lung injury; molecular pathways; treatment; therapeutic targets; inflammation; oxidative stress; respiratory disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Discovery and Development of Cisplatin 2.0
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 1825 | Submission Open
Keywords: cisplatin; cisplatin synthesis; mechanism of action; anticancer drugs; drug resistance; side effects
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Biology of Histamine Systems 2024
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 1752 | Submission Open
Keywords: histamine; molecular biology; genetics; mutations; disease; genomics; histamine signalling; synthesis; metabolism; isoforms; splicing; receptors; gene regulation; molecular structure; microbiome
(This special issue belongs to the Section Molecular Biology)
Gene Regulation and Genome Editing: New Insight in Plant Growth, Development, and Adaptation
edited by
submission deadline 31 May 2024 | 2 articles | Viewed by 1706 | Submission Open
Keywords: plant genes CRISPR/Cas9 editing technology; gene expression regulation; evolution of plant genes; gene function research; gene regulation mechanisms; machine learning genome data analysis and identification
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Medicine in Asthma and Allergic Diseases 2.0 submission deadline 31 May 2024 | 1 articles | Viewed by 1694 | Submission Open
Keywords: allergy; asthma; biologic treatments; molecular biomarkers; molecular diagnosis; endotypes; immunomodulation; vaccines
(This special issue belongs to the Section Molecular Immunology)
Signalling Pathway and Regulation of Oxidative Stress in Lung Diseases submission deadline 31 May 2024 | 1 articles | Viewed by 1566 | Submission Open
Keywords: oxidative stress; lung disease; airway epithelium; steroid resistance; antioxidant treatment
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Bladder Cancer: Molecular Advances in Pathology, Diagnostics and Therapeutics 2.0
edited by Georgios Gakis
submission deadline 31 May 2024 | 1 articles | Viewed by 1488 | Submission Open
Keywords: clinical relevance of molecular subtyping of bladder cancer; pathology and diagnosis of bladder cancer; evolution of bladder cancer markers on tumor organoids; simplified procedures to generate tumor organoids from urine samples; impedance-based discrimination of bladder cancer
(This special issue belongs to the Section Molecular Oncology)
Oral Cancer and Disease in Humans and Animals
edited by Maria Leonor Delgado and
submission deadline 31 May 2024 | 2 articles | Viewed by 1483 | Submission Open
Keywords: cancer biomarkers; mitosis; cell cycle; animal models; comparative pathology; cancer stem cell; cancer epidemiology; cancer risk factors; cancer biomarker; tissue microarray; immunohistochemistry; microarray; microRNA; molecular diagnostics; proteomics; tumor microenvironment; treatment response; targeted therapy; immunotherapy; translation cancer research; zoonosis; gross pathology
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Atherosclerosis: From Molecular Basis to Therapy
edited by Massimiliano Ruscica
submission deadline 31 May 2024 | 2 articles | Viewed by 1394 | Submission Open
Keywords: atherosclerosis; molecular basis; cardiovascular disease; artery disease; vascular dementia
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Investigating Molecular Footprint in Autism Spectrum Disorders: The Role of Genetics, Epigenetics and Neuroimaging in the Field
edited by and
submission deadline 31 May 2024 | 1 articles | Viewed by 1374 | Submission Open
Keywords: autism spectrum disorders; neurodevelopmental disorders; molecular underpinnings; epigenetic; genetic; and advanced neuroimaging; brain function; brain structure
(This special issue belongs to the Section Molecular Neurobiology)
Immunotherapy versus Immune Modulation of Leukemia
edited by Helga Maria Schmetzer
submission deadline 31 May 2024 | 1 articles | Viewed by 1369 | Submission Open
Keywords: leukemia; immunotherapy; immune modulation; antileukemic; drug resistance
(This special issue belongs to the Section Molecular Oncology)
Editorial Board Members’ Collection Series: Cancer Metastasis submission deadline 31 May 2024 | 2 articles | Viewed by 1354 | Submission Open
Keywords: biomarkers; liquid biopsy; premetastatic niche; angiogenesis; immune evasion and suppression; genetic and epigenetic determinants; chemoresistance; extracellular vesicles
(This special issue belongs to the Section Molecular Oncology)
Molecular Insights into Epigenetics in Cancer
edited by Giulia Pinton
submission deadline 31 May 2024 | 1 articles | Viewed by 1321 | Submission Open
(This special issue belongs to the Section Molecular Oncology)
Genotoxicity in Neurodegenerative Disease and Neuropsychiatric Disorders
edited by Glen E. Kisby, and David M Wilson III
submission deadline 31 May 2024 | 1 articles | Viewed by 1290 | Submission Open
Keywords: genomic instability; DNA damage; DNA damage response (DDR); DNA repair; apoptosis; cellular senescence; aging; neurodegeneration; psychiatric disorders
(This special issue belongs to the Section Molecular Neurobiology)
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