Oxidative Stress in Ear Damage

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 751

Special Issue Editor


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Guest Editor
1. Department of Otolaryngology, Chonnam National University Medical School, Gwangju 61469, Republic of Korea
2. Department of Otolaryngology, Gwangju Veterans Hospital, Gwangju 62284, Republic of Korea
Interests: tinnitus; facial nerve regeneration; tissue engineering & regeneration
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Dear Colleagues,

Reactive oxygen species levels may rise as a result of an imbalance between oxygen free radical production and antioxidant defense mechanisms. This can lead to an increase in reactive oxygen species, which can harm cells and tissues by peroxiding phospholipid membrane structures. In the beginning, the body produces more antioxidants, but if the oxidative stress is severe, antioxidant levels may drop. In this work, oxidative stress species expression levels in otologic illnesses are reported.

Prof. Dr. Chul Ho Jang
Guest Editor

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Keywords

  • oxidative stress
  • antioxidant
  • middle ear disease
  • inner ear disease
  • facial nerve disease

Published Papers (1 paper)

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Review

29 pages, 2322 KiB  
Review
A Consolidated Understanding of the Contribution of Redox Dysregulation in the Development of Hearing Impairment
by Xin Yi Yeo, Soohyun Kwon, Kimberley R. Rinai, Sungsu Lee, Sangyong Jung and Raekil Park
Antioxidants 2024, 13(5), 598; https://doi.org/10.3390/antiox13050598 - 13 May 2024
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Abstract
The etiology of hearing impairment is multifactorial, with contributions from both genetic and environmental factors. Although genetic studies have yielded valuable insights into the development and function of the auditory system, the contribution of gene products and their interaction with alternate environmental factors [...] Read more.
The etiology of hearing impairment is multifactorial, with contributions from both genetic and environmental factors. Although genetic studies have yielded valuable insights into the development and function of the auditory system, the contribution of gene products and their interaction with alternate environmental factors for the maintenance and development of auditory function requires further elaboration. In this review, we provide an overview of the current knowledge on the role of redox dysregulation as the converging factor between genetic and environmental factor-dependent development of hearing loss, with a focus on understanding the interaction of oxidative stress with the physical components of the peripheral auditory system in auditory disfunction. The potential involvement of molecular factors linked to auditory function in driving redox imbalance is an important promoter of the development of hearing loss over time. Full article
(This article belongs to the Special Issue Oxidative Stress in Ear Damage)
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