Non-Enzymatic Antioxidant Molecules and Their Defense Mechanisms
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Antioxidant Enzyme Systems".
Deadline for manuscript submissions: 30 September 2024 | Viewed by 3490
Special Issue Editors
Interests: antioxidant; anticancer; anti-inflammatory; phytochemical; small molecule
Special Issue Information
Dear Colleagues,
The imbalance between the production of reactive oxygen species (ROS) and the capacity of antioxidants to counteract the deleterious effects of oxidants, results in an increase of risk including multiple chronic disorders or cancer development. Various antioxidant enzymes and nonenzymatic antioxidants are engaged in the regulation of the oxidation/reduction (redox) balance. While enzymatic antioxidants function by converting oxidized metabolic products to hydrogen peroxide (H2O2) and then to water using cofactors through multi-step processes, nonenzymatic antioxidants intercept and terminate free radical chain reactions. Examples of nonenzymatic antioxidants are vitamin E, A, C, flavonoids, carotenoids, glutathione, plant polyphenols, uric acid, theaflavin, allyl sulfides, curcumin, melatonin, bilirubin, and polyamines. A better understanding of new aspects of well-known nonenzymatic antioxidants, discovery of new nonenzymatic antioxidants, and their interaction with the endogenous antioxidant signaling pathway would strengthen the relevance of their preventive or therapeutic use in health and diseases.
We invite researchers to submit research articles on new aspects of nonenzymatic antioxidants in the regulation of oxidative stresses and their action of mechanism. The topic includes the biological effects of non-enzymatic antioxidants and regulatory signaling pathway in the alleviation or prevention of chronic diseases.
Dr. Young‑Chang Cho
Dr. Su-Jin Park
Guest Editors
Manuscript Submission Information
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Keywords
- thiols
- glutathione
- vitamin C
- tocopherols
- phenols
- flavonoids
- carotenoids
- plants
- bacteria
- fungi
- animals
- human health