Microbiota, Oxidative Stress and Epithelial Diseases

Dear Colleagues,

We are pleased to serve as Guest Editors for the new Special Issue "Microbiota, Oxidative Stress and Epithelial Diseases."

Mounting evidence demonstrates the important role of oxidative stress in the pathogenesis of several medical conditions, including epithelial diseases. Elevated reactive oxygen species (ROS) can contribute, with different mechanisms, to their transformation and tumoral progression, including non-melanoma skin cancer, melanoma, head and neck squamous cell carcinoma, genital, colon, or breast malignancies. Moreover, several chronic benign inflammatory conditions involving epithelial tissues, such as atopic dermatitis, psoriasis, inflammatory bowel disease, or asthma, are associated with oxidative stress.

In the last few decades, microbiota has been identified as a major player in several human pathological conditions. Indeed, microbiota unbalance, named dysbiosis, is associated with the onset, progression, relapse, and resistance to therapies in several epithelial cancers. Moreover, alteration of the microbiota niches is closely linked to the pathogenesis of several inflammatory epithelial diseases.

It is well-known that dysbiosis can be associated with oxidative stress and/or inflammation. However, although their interplay has been somewhat suggested, the connection between microbiota, oxidative stress, and epithelial diseases is still a largely unexplored field.

This Special Issue welcomes original research and literature reviews concerning the connection between microbiota and oxidative stress in epithelial diseases.

Dr. Stefania Pizzimenti
Dr. Barbara Azzimonti
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• microbiota
• oxidative stress
• epithelial diseases
• non-melanoma skin cancer
• melanoma
• head and neck squamous cell carcinoma
• breast, genital, colon or other epithelial cancers
• atopic dermatitis or other skin inflammatory conditions
• inflammatory bowel disease
• asthma