Cellular ROS and Antioxidants: Physiological and Pathological Role
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "ROS, RNS and RSS".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 30814
Special Issue Editors
Interests: mitochondrial ROS signaling; oxidative stress; iron metabolism; mitochondrial dysfunction; nitric oxide metabolism; mitochondria targeted antioxidants, TCA cycle; oxoglutarate dehydrogenase complex; shock; inflammation; traumatic brain injury
Special Issues, Collections and Topics in MDPI journals
Interests: cell death; mitochondria; ROS; mitochondrial permeability transition; respiratory supercomplexes; cardiac ischemia-reperfusion; mitochondria-targeted ROS scavengers
Special Issues, Collections and Topics in MDPI journals
Interests: lung function and hemodynamic measurements; histology; mitochondrial function; targeted antioxidants; hypoxia; acute respiratory distress syndrome; pulmonary hypertension
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the past, reactive oxygen species (ROS) were considered the side products of cellular metabolism that could induce oxidative damage to biomolecules, leading to cellular dysfunction and death. However, studies during the last 30 years have provided strong evidence that ROS play an important role in intracellular signaling and regulate a number of important cellular functions, such as bactericidal activity, metabolic reaction, and gene expression, among others. Currently, it is commonly accepted that mitochondrial ROS play a predominant role in orchestrating ROS generated from other sources and regulating the ROS-dependent intracellular metabolism. This Special Issue invites submissions with a balanced consideration of the beneficial and deleterious impact of ROS, the identification of conditions (ROS types, sources, threshold concentrations) that switch between the beneficial and deleterious actions of ROS, considering the advantages and disadvantages of antioxidant therapy that aims to reduce the severity of diseases, and facilitating the recovery of patients. A comparison of targeted versus untargeted antioxidants and other mechanistic backgrounds helps to understand the pathophysiological mechanisms underlying ROS-mediated signaling pathways and different cell death mechanisms. The Special Issue invites original and review articles for publication.
Prof. Dr. Andrey V. Kozlov
Prof. Dr. Sabzali Javadov
Prof. Dr. Natascha Sommer
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- reactive oxygen and nitrogen species
- intracellular signaling
- oxidative stress
- iron metabolism
- mitochondrial dysfunction
- hypoxia
- inflammation
- targeted and untargeted antioxidants