Nutrient and Metabolite Profiling in Food Science

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Food Science and Technology".

Deadline for manuscript submissions: 20 June 2024 | Viewed by 1612

Special Issue Editor


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Guest Editor
Department of Food Science and Technology, University of Peloponnese, 24100 Antikalamos, Greece
Interests: food technology; food engineering; food safety; food quality; extra virgin olive oil; mycotoxins; fermented foods
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Special Issue Information

Dear Colleagues,

Metabolic profiling and metabolomics are novel technologies in modern systems biology that have been used to fingerprint and analyse the total chemical composition of food products. Untargeted metabolomics uses different analytical methodologies, and targeted metabolomics is similar to traditional analytics. "Metabolic profiling" focuses on metabolite classes, and "metabolic fingerprinting" refers to analysing the entire set of metabolites without prior knowledge of any of the components. Both metabolic techniques are utilised in the search for new quality and authenticity biomarkers, and they undoubtedly contribute to a greater biochemical understanding of foods, as well as a molecular comprehension of bioactivities or changes in food production processes.

In this Special Issue, we will be addressing the area of nutrient and metabolic profiling in food science and technology. Metabolomics has been used in the evaluation of several food safety, food quality, authenticity, and traceability issues. It can be also used to define hundreds of compounds in foods, identify food byproducts in human biofluids or tissues, characterise nutrient deficits or excesses, follow biochemical reactions to dietary treatments, and track long-term or short-term eating habits. Hence, this research area is very significant.

This Special Issue aims to study both qualitative and quantitative analytical methodologies used to examine food metabolites holistically in connection to medicinal and nutritive variables. A particular emphasis will be given to the analytical breakthroughs that can be used to boost food metabolome coverage, as well as improve detection or extraction methodologies.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the application of metabolomics in food systems, such as food resources, food processing, and the human diet.

Prof. Dr. Theodoros Varzakas
Guest Editor

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Keywords

  • metabolite profiling
  • metabolomics
  • foods
  • nutrition
  • functional foods
  • natural products
  • food chemistry
  • food byproducts
  • eating habits
  • nutrient deficits or excesses
  • food security and sustainability

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Published Papers (2 papers)

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Review

21 pages, 834 KiB  
Review
Exploring Vitamin D Synthesis and Function in Cardiovascular Health: A Narrative Review
by Gilda Aiello, Mauro Lombardo and Sara Baldelli
Appl. Sci. 2024, 14(11), 4339; https://doi.org/10.3390/app14114339 - 21 May 2024
Viewed by 423
Abstract
Vitamin D plays a crucial role in the human body, influencing a wide range of physiological processes from bone health to immune function. The complex biochemical pathways involved in the synthesis, metabolism, and action of Vitamin D are explored, emphasizing its importance in [...] Read more.
Vitamin D plays a crucial role in the human body, influencing a wide range of physiological processes from bone health to immune function. The complex biochemical pathways involved in the synthesis, metabolism, and action of Vitamin D are explored, emphasizing its importance in nutrition and food technology. This review also investigates the regulatory mechanisms that control Vitamin D metabolism and its systemic effects on calcium homeostasis, cell proliferation, differentiation, and immune modulation. The role of Vitamin D3 in regulating blood pressure and atherosclerosis in the onset of cardiovascular disorders is discussed. Given the importance of Vitamin D in food science and technology, the regulatory mechanisms that control Vitamin D metabolism and its systemic effects on calcium homeostasis are also investigated, integrating innovative approaches and advanced technologies to improve human health through nutrition. Additionally, the review assesses the influence of food processing on Vitamin D levels and discusses cutting-edge technologies as innovative strategies to mitigate Vitamin D loss during food processing. This comprehensive exploration aims to improve our understanding of the biochemical pathways of Vitamin D and its relevance to food science, contributing to the development of new strategies for food fortification and the promotion of optimal health through diet. Full article
(This article belongs to the Special Issue Nutrient and Metabolite Profiling in Food Science)
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23 pages, 1058 KiB  
Review
A Narrative Review of Metabolomic Insights into Olive Oil’s Nutritional Value
by Marta Gonçalves, María Rodríguez-Pérez, Anna Calabrò, Emma Burgos-Ramos, Giulia Accardi and Paula Silva
Appl. Sci. 2024, 14(10), 4203; https://doi.org/10.3390/app14104203 - 15 May 2024
Viewed by 885
Abstract
This review explores the critical role of advanced metabolomic methodologies in interpreting the complex relationship between the bioactive compounds in olive oil and their health benefits. Olive oil, the cornerstone of the Mediterranean diet, is renowned for its numerous health benefits, including anti-inflammatory, [...] Read more.
This review explores the critical role of advanced metabolomic methodologies in interpreting the complex relationship between the bioactive compounds in olive oil and their health benefits. Olive oil, the cornerstone of the Mediterranean diet, is renowned for its numerous health benefits, including anti-inflammatory, antioxidant, and cardioprotective properties. This review begins with an overview of the importance of olive oil for nutrition and health, followed by a detailed discussion of the key metabolites that contribute to its therapeutic potential. It further explores the evolution of analytical techniques in metabolomics from traditional methods to cutting-edge technologies, such as mass spectrometry and nuclear magnetic resonance spectroscopy, which have enhanced our understanding of the complex composition of olive oil. This review highlights how these advanced analytical findings correlate with the known health properties of olive oil and presents case studies in which these methodologies have led to new insights. Finally, we address the challenges in standardizing these techniques and discuss future research directions, underscoring the significance of metabolomics in nutritional science and public health. This comprehensive analysis aims to provide a deeper understanding of the health benefits of olive oil, informed by the latest advancements in analytical methodologies. Full article
(This article belongs to the Special Issue Nutrient and Metabolite Profiling in Food Science)
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