Dermoscopy in Skin Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".

Deadline for manuscript submissions: 14 February 2025 | Viewed by 1278

Special Issue Editors


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Guest Editor
Department of Health Science, University of Eastern Piedmont, 13100 Novara, Italy
Interests: non-melanoma skin cancer; field cancerization; organ transplant recipients; melanoma
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Health Science, University of Eastern Peidmont, Novara, Italy
Interests: melanoma; non-melanoma skin cancer; photoaging; cutaneous lymphomas
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Skin cancers are very frequent worldwide and account for a large number of clinical issues requiring dermatological evaluations. Despite the fact that some of these neoplasms can be easily diagnosed, dermoscopy examination is mandatory in order to properly recognize and classify cutaneous lesions.

The development of dermoscopy has led to the identification of a large number of different pathognomonic patterns, many of which have already been published. Interestingly, dermoscopy might provide a useful tool to differentiate between certain skin tumors and even between their diverse types; moreover, it can also be of help in the follow-up after surgery and medical treatment.

Of note, numerous methods of automatic and AI-based readings of dermoscopy have been recently developed, with controversial results. On the other hand, comparisons between dermoscopy and other non-invasive diagnostic tools have been reported, and we are strongly convinced of their importance.

This Special Issue will discuss the latest updates on the usefulness of dermoscopy, both in the diagnostic process and in the follow-up of skin tumors, and it is also focused on reporting novel developments in the field of dermatology.

You may choose our Joint Special Issue in Dermato.

Dr. Elisa Zavattaro
Prof. Dr. Paola Savoia
Guest Editors

Manuscript Submission Information

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Keywords

  • dermoscopy
  • skin cancer
  • differential diagnosis
  • dermoscopy patterns
  • non-invasive diagnostic tool

Published Papers (1 paper)

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Research

11 pages, 3804 KiB  
Article
Reflectance Confocal Microscopy and Dermoscopy of Facial Pigmented and Non-Pigmented Actinic Keratosis Features before and after Photodynamic Therapy Treatment
by Ewelina Mazur, Dominika Kwiatkowska and Adam Reich
Cancers 2023, 15(23), 5598; https://doi.org/10.3390/cancers15235598 - 27 Nov 2023
Viewed by 790
Abstract
Actinic keratosis (AK), due to its widespread prevalence, as well as the possibility of progression to an invasive form of squamous cell carcinoma, requires treatment regardless of the clinical stage. New imaging techniques, such as in vivo reflectance confocal microscopy (RCM), significantly increase [...] Read more.
Actinic keratosis (AK), due to its widespread prevalence, as well as the possibility of progression to an invasive form of squamous cell carcinoma, requires treatment regardless of the clinical stage. New imaging techniques, such as in vivo reflectance confocal microscopy (RCM), significantly increase the accuracy of diagnosis and allow noninvasive evaluation of the therapeutic efficacy of the ongoing treatment. Our objective was to evaluate the prevalence of specific (video)dermoscopy and RCM features of pigmented and classical subtypes of AK before and after photodynamic therapy (PDT) treatment. We included patients with facial grade II AKs (25 pigmented, 275 non-pigmented) were included in the study. Skin lesions were evaluated by (video)dermoscopy and RCM at the baseline and three months after PDT. In classic AK, the most frequent dermoscopic findings were fine wavy vessels (96%), scale (92%), microerosions (48%), and “strawberry” pattern (36%), while pigmented AK was characterized mostly by “rhomboidal pattern” (80%), scale (60%), white globules (48%), “jelly sign”, and superficial pigmentation (40%). RCM’s most characteristic classic AK findings were abnormal honeycomb pattern in the spinous layer, epidermal inflammatory infiltrate, and solar elastosis that were present in 96% of lesions. Pigmented AKs presented mostly with dark central areas of parakeratosis (72%), mottled pigmentation (72%), dermal inflammatory infiltrate (64%), solar elastosis (60%), and abnormal honeycomb pattern in the spinous layer (56%). Dermoscopically, PDT resulted in complete disappearance of the “rhomboidal pattern” in both classical and pigmented AKs, “starburst pattern” and “jelly sign” in classical AKs, and inner gray halo, “rosette sign” and central crust in pigmented AKs. Three months after one PDT session, RCM evaluation showed mostly solar elastosis in both classical and pigmented AK subtypes, epidermal inflammatory infiltrate in classical AKs, and dermal inflammatory infiltrate in pigmented AKs. New noninvasive imaging techniques such as RCM and (video)dermoscopy can help practitioners better visualize the efficacy of the ongoing PDT treatment in either classical or pigmented AK subtypes. Full article
(This article belongs to the Special Issue Dermoscopy in Skin Cancer)
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