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Chemosensors
Special Issues
Rapid Point-of-Care Testing Technology and Application
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Rapid Point-of-Care Testing Technology and Application

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "(Bio)chemical Sensing".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 1417

Special Issue Editors

Dr. Florina S. Iliescu

E-Mail Website
Guest Editor
National Institute for Research and Development in Microtechnologies (IMT Bucharest), Voluntari, Romania
Interests: diagnostic and therapeutic methods; microfluidics; biosensors
Special Issues, Collections and Topics in MDPI journals
Dr. Zenovia Moldovan

E-Mail Website
Guest Editor
Department of Analytical Chemistry, University of Bucharest, Bucharest, Romania
Interests: analytical chemistry; statistics; diagnostics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

It is a great honour to invite you to contribute to this Special Issue, entitled "Rapid Point-of-Care Testing Technology and Application". Since the first developed system in 1972 and the introduction of the term in the early 1980s, POCT has been widely accepted as a viable and valuable alternative to traditional laboratory-based testing, especially when rapid medical decisions are required or in low-resource and remote settings. Nevertheless, researchers are continuously involved in the process of understanding how new micro- and nanotechnologies could further improve traditional POCT diagnostics. With researchers' contributions to developing new ways of detecting target analytes at small volumes, POCT will be ASSURED (affordable, sensitive, specific, user-friendly, rapid and robust, equipment-free and deliverable to end-users). Eventually, POCT will become an essential tool that can significantly contribute to reduced morbidity, mortality and an increased quality of life. Therefore, we invite you to submit your research studies and help bring POCT to the next level: personalised active disease management.

Dr. Florina S. Iliescu
Dr. Zenovia Moldovan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • POCT
  • diagnostic
  • microfluidics
  • biosensors
  • antibody
  • immune response
  • prophylaxis

Published Papers (2 papers)

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Research

11 pages, 944 KiB  
Article
Portable Sensing Platform for the Visual Detection of Iodide Ions in Food and Clinical Samples
by Aizaz Khan, Ali Turab Jafry, Huma Ajab, Asim Yaqub, Shahaab Jilani, Dildar Hussain and Naseem Abbas
Chemosensors 2024, 12(6), 102; https://doi.org/10.3390/chemosensors12060102 - 5 Jun 2024
Viewed by 86
Abstract
The detection of iodide ions (I−), despite challenges due to low concentrations and potential masking, is crucial for studying physiological processes and diagnosing diseases. A colorimetric sensor was developed to improve I− ion monitoring and facilitate on-site detection based on [...] Read more.
The detection of iodide ions (I−), despite challenges due to low concentrations and potential masking, is crucial for studying physiological processes and diagnosing diseases. A colorimetric sensor was developed to improve I− ion monitoring and facilitate on-site detection based on filter paper, which is a cost-effective platform. The sensor observed color changes in response to the exposure of hydrogen peroxide (H2O2), 3,3′,5,5′-tetramethylbenzidine (TMB), from colorless to yellowish brown. The sensor demonstrated a detection limit of 0.125 × 10−6 M for I− ions in a relatively wide range of 0.01 to 15 × 10−6 M under optimized conditions including gel concentration, temperature, incubation time, TMB and H2O2 concentration, and pH. Furthermore, the proposed sensor was successfully employed in a variety of applications, such as biological (urine and blood serum), food (egg yolk and snacks), and environmental samples (tap water). The study established effective recoveries in complex media for visual on-site I− ion monitoring, indicating the developed assay as a potent, affordable, and practical platform. Full article
(This article belongs to the Special Issue Rapid Point-of-Care Testing Technology and Application)
12 pages, 3870 KiB  
Article
Rapid and Sensitive Detection of Influenza B Virus Employing Nanocomposite Spheres Based on Ag-Doped ZnIn2S4 Quantum Dots
by Jia-Xuan Hu, Li-Bang Zhu, Sheng-Tong Wu and Shou-Nian Ding
Chemosensors 2024, 12(4), 68; https://doi.org/10.3390/chemosensors12040068 - 19 Apr 2024
Viewed by 849
Abstract
Lateral flow immunoassay (LFIA) technology serves a significant role as a simple and rapid biosensor in the detection of influenza viruses. The focus of this study is the development of a rapid and convenient screening method for influenza B virus (IBV) proteins using [...] Read more.
Lateral flow immunoassay (LFIA) technology serves a significant role as a simple and rapid biosensor in the detection of influenza viruses. The focus of this study is the development of a rapid and convenient screening method for influenza B virus (IBV) proteins using a fluorescence lateral flow biosensor based on Ag-doped ZnIn2S4 quantum dots (Ag: ZIS QDs) as signal reporters. These Ag: ZIS QDs-emitting orange fluorescence are loaded onto dendritic mesoporous silica nanoparticles (DMSNs) and are further coated with a layer of silica shell to form a core–shell structured composite nanomaterial (SiO2 @ Ag: ZIS QDs @ DMSNs). The orange fluorescence effectively eliminates the interference of blue background fluorescence, significantly enhancing the detection sensitivity. This technology demonstrates outstanding performance in the immediate detection of IBV, with a minimum detection limit of 1 ng/mL, compared to the traditional colloidal gold strip with a detection limit of 6 ng/mL. Furthermore, both intra-assay and inter-assay coefficients of variation (CV) are less than 9%. This method holds promise for wide application in early diagnosis, epidemiological investigation, and epidemic surveillance of IBV. Full article
(This article belongs to the Special Issue Rapid Point-of-Care Testing Technology and Application)
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