Probing the Role of Metabolomics to Unveil the Molecular Landscape of Cardiovascular Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 20 August 2024 | Viewed by 2666
Special Issue Editors
Interests: metabolomics; lipidomics; cardiovascular diseases; biostatistics
Special Issue Information
Dear Colleagues,
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality. Despite significant advances in medical interventions and treatments, our understanding of the onset, progression, and related comorbidities of CVD remains incomplete. Thus, understanding of the molecular landscape and mechanisms involved in CVD and their interplay with related comorbidities are highly sought. Metabolomics enables the simultaneous measurement of hundreds of metabolites, leveraging the understanding of the molecular basis of CVD phenotypes. Recognising the importance of bridging the knowledge gap in this area, this Special Issue aims to gather research that sheds light on the intricate relationship between metabolisms and cardiovascular diseases.
This Special Issue will be a dedicated collection of relevant reviews or original articles using metabolomics to understand the molecular landscape of CVD and related comorbidities or risk factors, e.g., diabetes, dyslipidemias, obesity, hypertension, lifestyle, or nutrition. The scope encompasses a broad range of topics, including, but not limited to, the following:
- Metabolic risk factors and their impact on CVDs;
- Metabolic syndrome and its association with CVDs;
- Molecular mechanisms linking metabolism to CVD pathogenesis;
- Novel diagnostic and therapeutic strategies targeting metabolic dysregulation in CVDs;
- Comorbidities, such as diabetes, obesity, and dyslipidemia, concerning CVDs;
- Metabolic profiling and biomarker discovery for early detection and prognosis of CVDs;
- Bioinformatic and network analysis techniques to elucidate the molecular pathways involved in CVDs;
- Nutritional interventions and lifestyle modifications for prevention and management of CVDs.
By bringing together high-quality research expertise in the field, we aim to provide a comprehensive overview of the latest contribution of metabolomics for the unveiling of the molecular basis of CVD. We cordially invite researchers to submit their work and help showcase the added value of metabolomics in cardiovascular research. We also encourage manuscripts that address crucial technical issues, such as standardisation and harmonisation across various stages of research, including sample handling, data analysis, reporting, and sharing.
Dr. Sílvia O. Diaz
Dr. Antonio Barros
Guest Editors
Manuscript Submission Information
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Keywords
- cardiovascular disease
- metabolomics
- lipidomics
- metabolic phenotypes
- systems biology