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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovative Approaches to Understand, Prevent and Eradicate Biofilms and Related Infections—a New Look from Natural Compounds to Nanotechnology
edited by
submission deadline 15 Jun 2024 | 2 articles | Viewed by 3084 | Submission Open
Keywords: biofilm; natural compounds; nanotechnology; antibiotic resistance; mechanism of compound; bacteria; fungi; public health
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Research on Skeletal Muscle Diseases submission deadline 15 Jun 2024 | 4 articles | Viewed by 2616 | Submission Open
Keywords: muscle contraction; calcium regulation; desease-causing mutations; cross-bridge cycling and kinetics; thin filament; ATPase activity; actin– myosin interaction; therapeutic approaches
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Biodegradable Polymer: Structure, Properties and Applications submission deadline 15 Jun 2024 | 3 articles | Viewed by 2533 | Submission Open
Keywords: biodegradable polymers; synthesis; structure; properties; applications
(This special issue belongs to the Section Materials Science)
Regulation Mechanism of Osteoblast/Osteoclast Differentiation submission deadline 15 Jun 2024 | 2 articles | Viewed by 2511 | Submission Open
Keywords: bioactive compound; bone formation; bone remodeling; bone diseases; cancer; osteoblast; osteoclast
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Carbohydrate Structures in Targeted Drug Delivery
edited by Rosana Ribić
submission deadline 15 Jun 2024 | 1 articles | Viewed by 2429 | Submission Open
Keywords: carbohydrates; targeted drug delivery; drug– target interactions; glycoconjugates; glyconanoparticles; lipid-based drug delivery systems
(This special issue belongs to the Section Molecular Pharmacology)
Assimilate Production and Allocation in Plants under Abiotic Stress 2.0
edited by , and
submission deadline 15 Jun 2024 | 3 articles | Viewed by 2365 | Submission Open
Keywords: plant response; plant metabolism; abiotic stresses; drought; heat; cold; salt; heavy metal; high-light; low-light
(This special issue belongs to the Section Molecular Plant Sciences)
State-of-the-Art Molecular Immunology in Chile, 2nd Edition submission deadline 15 Jun 2024 | 2 articles | Viewed by 2151 | Submission Open
Keywords: innate immunity; adaptive immunity; host– pathogen interactions; immunopathology; osteoimmunology; immunosenescence; immunotherapy; antibody; vaccines; Chile
(This special issue belongs to the Section Molecular Immunology)
Molecular Research on Reproductive Toxicology
edited by Chiara Maria Motta
submission deadline 15 Jun 2024 | 2 articles | Viewed by 2115 | Submission Open
Keywords: environmental contamination; aquatic organisms; psychotropic drugs; gametogenesis; development; teratogenesis; gene expression; behavioral effects; oxidative stress; epigenotoxic effects; detoxification; bioaccumulation
(This special issue belongs to the Section Molecular Toxicology)
Epilepsy Research and Antiepileptic Drugs 2.0
edited by
submission deadline 15 Jun 2024 | 2 articles | Viewed by 1900 | Submission Open
Keywords: refractory epilepsy; pharmacoresistant epilepsy; antiepileptic drug; seizure; molecular mechanisms; prognosis; pharmacogenomics
(This special issue belongs to the Section Molecular Pharmacology)
Gynecological Cancer: Targeted Therapeutics and Future Perspectives
edited by Angela Santoro
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1896 | Submission Open
Keywords:   molecular background;   precision medicine;   histomolecular diagnosis;   targeted therapies;   clinical trials;   overall survival;   disease-free survival;   gynecological cancer;   whole genomic assay;   molecular biomarkers
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Effect of Food-Derived Compounds on Brown Fat Cell Function
edited by
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1593 | Submission Open
Keywords: brown adipocyte; beige adipocyte; nutrients; food-derived components; thermogenesis; energy homeostasis; inflammation; obesity; diabetes; insulin resistance; metabolic syndrome; adipokines; lipid and carbohydrate metabolism
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Molecular and Metabolic Insights into Neuroinflammation and Neurodegeneration
edited by and Marika Lanza
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1508 | Submission Open
Keywords: Parkinson’ s disease; Alzheimer’ s disease; metabolism; inflammation; neurodegeneration; drug discovery; pharmacological therapy
(This special issue belongs to the Section Molecular Neurobiology)
Bio-Nanopesticides
edited by
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1457 | Submission Open
Keywords: bio-nanopesticides; sustainable agriculture; pest control; plant protection; nanotechnology; eco-friendly solutions; environmental impact; toxicity
(This special issue belongs to the Section Molecular Nanoscience)
Molecular Advances in Muscular Dystrophy
edited by Sonia Albini
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1306 | Submission Open
Keywords: (Muscular Dystrophy) MD; muscle regeneration; epigenetic regulators; biotherapeutic approaches
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances in Oral Biofilms
edited by José Antonio Poli De Figueiredo and Carlos Estrela
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1281 | Submission Open
Keywords: biofilms; oral tissues; dental tissues; molecular basis; dentine; enamel; microorganisms; prevention; treatment
(This special issue belongs to the Section Molecular Microbiology)
Advances in the Molecular Mechanisms in Gastrointestinal Tumorigenesis and Treatment submission deadline 15 Jun 2024 | 1 articles | Viewed by 1246 | Submission Open
(This special issue belongs to the Section Molecular Oncology)
Perspective Research on Antimicrobial Activities of Metals and Metal-Based Compounds
edited by Christopher Rensing
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1230 | Submission Open
Keywords: metal-based nanoparticles; antibiotics; nanomedicine; mechanism of antibacterial activity
(This special issue belongs to the Section Molecular Microbiology)
Stress-Related Disorders and Depression: From Molecular Basis to Therapy (2nd Edition) submission deadline 15 Jun 2024 | 1 articles | Viewed by 1161 | Submission Open
Keywords: psychobiology of stress; depression; posttraumatic stress disorder; anxiety disorders; animal models; biogenic monoamines; glucocorticoids; inflammation; antidepressant and anxiolytic drugs
(This special issue belongs to the Section Molecular Neurobiology)
The Role of Antithrombin in Blood Disorders
edited by
submission deadline 15 Jun 2024 | 1 articles | Viewed by 931 | Submission Open
Keywords: antithrombin; antithrombin deficiency; thrombosis; haemophilia; laboratory tests; molecular genetics; anticoagulant therapy  
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Macromolecules and Hydrogel Formulations: Synthesis, Characterization, Pharmacological Effects and Possible Environmental Applications 2.0
edited by
submission deadline 15 Jun 2024 | 1 articles | Viewed by 862 | Submission Open
Keywords: (cationic) antibacterial nanoparticles; (cationic) anticancer nanoparticles; water-soluble bioactive nanoparticles; cross-linked materials (resins); (cationic) solubilizing macromolecules; swelling polymers; hydrogels formulations; drug delivery systems; environmental application of resins; spectroscopic characterization; rheological experiments; swelling and porosity characteristics; water loss studies; kinetic mathematical models; multivariate analyses (PCA)
(This special issue belongs to the Section Macromolecules)
Advances in Developmental Neurotoxicology
edited by
submission deadline 15 Jun 2024 | 1 articles | Viewed by 753 | Submission Open
Keywords: developmental neurotoxicology; neurodevelopmental models; neurotoxicants; neurodevelopmental disorders
(This special issue belongs to the Section Molecular Toxicology)
Molecular Thermodynamics of Nanostructured Materials: Trends and Prospects
edited by Fernando J.A.L. Cruz and
submission deadline 15 Jun 2024 | Viewed by 746 | Submission Open
Keywords: nanomaterials; thermodynamics; applications; synthesis
(This special issue belongs to the Section Molecular Nanoscience)
Advanced Flame Retardant Polymeric Materials 2.0
edited by
submission deadline 15 Jun 2024 | 1 articles | Viewed by 597 | Submission Open
Keywords: flame retardants; flame retardancy; fire resistance; fire safety; bio-based flame retardants; flame-retardant coatings; hybrid materials; polymer composites; multi-functionality; fire behaviors; smoke suppression; toxicity reduction; flame-retardant mechanisms
(This special issue belongs to the Section Macromolecules)
Original Approaches and Advanced Techniques in Molecular Magnetism Research
edited by Sergey L. Veber
submission deadline 15 Jun 2024 | 1 articles | Viewed by 577 | Submission Open
Keywords: molecular magnetism; coordination chemistry; spin-crossover materials; single-molecule magnets; magnetocaloric/magnetoelectric materials; magnetic field effects; spectroscopy; large-scale facilities; extreme conditions; computational approaches
(This special issue belongs to the Section Materials Science)
Natural Compounds in Cancer Therapy and Prevention 2.0 submission deadline 15 Jun 2024 | 1 articles | Viewed by 550 | Submission Open
Keywords: cancer therapy cancer prevention; natural compounds; metastasis; immunomodulation; adjuvant therapy; preventive therapy; drug discovery; natural drugs
(This special issue belongs to the Section Molecular Pharmacology)
Tumor Microenvironment in Cancer Cell Metastasis
edited by
submission deadline 15 Jun 2024 | Viewed by 370 | Submission Open
Keywords: tumour microenvironment; extracellular matrix; actin cytoskeleton; cancer cell metastasis
(This special issue belongs to the Section Molecular Oncology)
Modification and Functionalization of Polymers, Biopolymers, and Additives for Packaging Materials
edited by and Agnieszka Piegat
submission deadline 15 Jun 2024 | Viewed by 251 | Submission Open
Keywords: active packaging; biopolymers; bioactive additives; sustainable packaging; nanomaterials; antimicrobial packaging; antioxidant packaging; bio-based materials; functionalized packaging materials; characteristics of improved packaging performance
(This special issue belongs to the Section Materials Science)
Plant Bioactive Substances and Potential Applications submission deadline 15 Jun 2024 | Viewed by 245 | Submission Open
Keywords: bioactive compounds; chemical composition; natural-based extracts; biological activity; antimicrobial activity; antioxidant effect
(This special issue belongs to the Section Molecular Pharmacology)
Gene Transfer in Brain Disorders
edited by , Lluís Samaranch and Anne-Marie Duchemin
submission deadline 15 Jun 2024 | Viewed by 239 | Submission Open
Keywords: intellectual disability; neurodegenerative disorders; psychiatric diseases; gene transfer; AAV
(This special issue belongs to the Section Molecular Neurobiology)
Latest Advances in Proteomics in De- and Recellularized Tissue
edited by Karl Herbert Hillebrandt and
submission deadline 15 Jun 2024 | Viewed by 226 | Submission Open
Keywords: tissue and organ decellularisation; tissue and organ recellularisation; proteomics; matrisome; 3D matrix-based culture models
(This special issue belongs to the Section Molecular Informatics)
New Molecular Progression of Neuro-Orthopaedics: Musculoskeletal Disorders Caused by Neuromuscular Diseases
edited by
submission deadline 15 Jun 2024 | Viewed by 219 | Submission Open
Keywords: muscle regeneration; clinical application; cerebral palsy; stroke; spina bifida; molecular structure; spasticity; paresis; contractures; central and peripheral nervous system
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Role of Natural Products in Neurodegenerative Diseases submission deadline 15 Jun 2024 | Viewed by 208 | Submission Open
Keywords: neurodegeneration; autophagy; polyphenols; acetylation; oxidative stress; natural products
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Recent Research of Chemokines in Health and Disease submission deadline 15 Jun 2024 | Viewed by 191 | Submission Open
Keywords: chemokines; inflammation; cancer; infection; angiogenesis; fibrosis; hematopoiesis
(This special issue belongs to the Section Molecular Biology)
Insights into Antioxidant Compounds: From Extraction to Mechanism of Action submission deadline 15 Jun 2024 | Viewed by 171 | Submission Open
Keywords: antioxidants; oxidative stress; extraction methods; bioactive compounds; molecular mechanisms; reactive oxygen species (ROS); signaling pathways; therapeutic applications
(This special issue belongs to the Section Biochemistry)
Molecular Immunology of Liver Diseases
edited by
submission deadline 15 Jun 2024 | Viewed by 167 | Submission Open
Keywords: steatotic liver disease; metabolic-associated liver disease; alcohol-associated liver disease; inflammation; innate immunity; adaptive immunity; liver fibrosis; biomarker discovery
(This special issue belongs to the Section Molecular Immunology)
Recent Advances in Molecular Pathology, Drug Resistance and Diagnostics of Human Fungal Diseases
edited by
submission deadline 15 Jun 2024 | Viewed by 142 | Submission Open
Keywords: host-fungal interaction; pathogenesis; virulence; antifungal immunity; antifungal resistance; molecular diagnosis
(This special issue belongs to the Section Molecular Microbiology)
Molecular and Metabolic Insights into Age-Related Macular Degeneration
edited by Joanne Matsubara
submission deadline 15 Jun 2024 | Viewed by 130 | Submission Open
Keywords: non-exudative (dry) AMD; exudative (wet) AMD; subretinal fibrosis; pathogenesis; RPE; choroid; Bruch’ s membrane; senescence; ophthalmic imaging
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Toxic Effects of Nanoparticles
edited by
submission deadline 15 Jun 2024 | Viewed by 124 | Submission Open
(This special issue belongs to the Section Molecular Toxicology)
Molecular Advances in Water-Soluble Polymers: From Characterization, Surface Behaviour to Application submission deadline 15 Jun 2024 | Viewed by 82 | Submission Open
Keywords: water-soluble polymers; colloidal system stability; polymer chain conformation; toxic substances separation; suspension flocculation; polymer adsorption; surface behavior
(This special issue belongs to the Section Macromolecules)
Plant Rhizobium Interactions
edited by
submission deadline 16 Jun 2024 | 6 articles | Viewed by 5930 | Submission Open
(This special issue belongs to the Section Molecular Plant Sciences)
Immunological and Molecular Networks in the Skin and Skin Diseases
edited by
submission deadline 16 Jun 2024 | 2 articles | Viewed by 5300 | Submission Open
Keywords: skin diseases; skin immunology; skin inflammation; skin aging; skin cancers; cytokine/chemokine networks; molecular signaling pathways; non-coding RNAs; targeted therapies
(This special issue belongs to the Section Molecular Immunology)
Bioluminescent and Fluorescent Proteins: Molecular Mechanisms and Modern Applications 4.0
edited by
submission deadline 16 Jun 2024 | 3 articles | Viewed by 4546 | Submission Open
Keywords: bioluminescence; luciferase; photoprotein; luciferin; coelenterazine; GFP; GFP-like proteins; immuno and hybridization assays; BRET and FRET assays; imaging
(This special issue belongs to the Section Molecular Biophysics)
Hepatocellular Carcinoma: Latest Research in Pathogenesis, Detection and Treatment 2.0 submission deadline 16 Jun 2024 | 2 articles | Viewed by 3166 | Submission Open
Keywords: human hepatocellular carcinoma (HCC); tumour microenvironment; biomarkers; immunotherapy; epigenetic modulators; precise medicine; combination strategies
(This special issue belongs to the Section Molecular Oncology)
Innovative Approaches for Targeted Cancer Therapies
edited by
submission deadline 16 Jun 2024 | 2 articles | Viewed by 2860 | Submission Open
(This special issue belongs to the Section Molecular Oncology)
Chronic Liver Disease: Latest Research in Pathogenesis, Detection and Treatment 2.0 submission deadline 16 Jun 2024 | Viewed by 364 | Submission Open
Keywords: NASH/NAFLD: pathogenesis; detection; and treatment; hepatocellular carcinoma: pathogenesis; detection; and treatment; inflammation in liver disease; 3D liver models; microbiota and liver disease; mechanisms of damage and repair: ischemia-reperfusion injury; cellular pathology in acute and chronic liver damage of different origin; biomarkers in liver disease: emerging methods and potential applications; immunology in the liver— from homeostasis to disease
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
The Mast Cell in Breast Cancer: Friend or Foe
edited by
submission deadline 16 Jun 2024 | Viewed by 209 | Submission Open
Keywords: mast cells; tumor growth; oncogenes; cytokines; VEGF; breast cancer
(This special issue belongs to the Section Molecular Oncology)
Advances, Pitfalls and Future Perspectives for CRISPR/Cas9 Mediated Genome Editing 3.0 submission deadline 20 Jun 2024 | 6 articles | Viewed by 18137 | Submission Open
(This special issue belongs to the Section Molecular Biology)
Wheat Genetics and Genomics 2.0
edited by
submission deadline 20 Jun 2024 | 11 articles | Viewed by 13297 | Submission Open
Keywords: wheat; genetics; molecular breeding; genome variation; multiomics
(This special issue belongs to the Section Molecular Plant Sciences)
Lung Cancer: From Molecular Mechanisms to Novel Therapeutics submission deadline 20 Jun 2024 | 7 articles | Viewed by 12634 | Submission Open
Keywords: lung cancer; oncogene; targeted therapy; immunotherapy; predictive biomarkers; liquid biopsy
(This special issue belongs to the Section Molecular Oncology)
Highlights in Pathophysiology of the Musculoskeletal System 2.0 submission deadline 20 Jun 2024 | 3 articles | Viewed by 12464 | Submission Open
Keywords: musculoskeletal; skeletal; tendon; ligament; intervertebral; articular cartilage; osteoarthritis; rheumatoid arthritis; sarcopenia; muscle wasting; osteoporosis; bone necrosis; synovium; pain; inflammation
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
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