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Migraines: Diagnosis and Treatment
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Migraines: Diagnosis and Treatment

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: closed (20 March 2024) | Viewed by 1717

Special Issue Editors

Dr. Vincenzo Raieli

E-Mail Website
Guest Editor
Child Neuropsychiatry Unit, ISMEP- ARNAS CIVICO, Palermo, Italy
Interests: aura and migraine; headaches in younger children; cranial autonomic symptoms and pediatric migraine; primary pediatric headaches
Special Issues, Collections and Topics in MDPI journals
Dr. Vittorio Sciruicchio

E-Mail Website
Guest Editor
Children Epilepsy and EEG Centre, S. Paolo Hospital, Bari, Italy
Interests: pediatric migraine; epilepsy in childhood; EEG and neurological diseases; fibromyalgia and children
Special Issues, Collections and Topics in MDPI journals
Dr. Andrea Santangelo

E-Mail Website
Guest Editor
1. Pediatric Neurology, Department of Pediatrics, AOUP Santa Chiara Hospital, Pisa, Italy
2. Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy
Interests: diabetes; risk factors; metabolic diseases; epilepsy; next generation sequencing; pediatric neurology; genetic association studies

Special Issue Information

Dear Colleagues,

Migraines have been a longstanding concern in the medical field, representing the most common neurological disorder. Despite extensive research, their precise causes and optimal treatment strategies remain mainly elusive. This Special Issue delves into the diagnosis and treatment of migraines, building upon the rich history of scientific inquiry in this area.

We aim to consolidate the latest advancements in understanding and managing migraines, and will explore innovative approaches to diagnosis, cutting-edge therapeutic interventions, and emerging trends in the field. By gathering diverse perspectives, this issue seeks to foster collaboration and improve outcomes for migraine sufferers.

This Special Issue will showcase groundbreaking research on migraines, highlighting studies that employ advanced diagnostic techniques, genetic analyses, and personalized medicine approaches. We will also include pioneering investigations into the role of lifestyle modifications, novel pharmaceutical agents, and neuromodulation techniques in migraine management. A wide range of contributions will be welcomed, including comprehensive reviews that synthesize existing knowledge, case series that shed light on unique patient experiences, and meta-analyses that provide robust evidence on specific diagnostic or therapeutic interventions. By encompassing a variety of research methodologies, we aim to offer a comprehensive overview of the current state of migraine research and treatment.

Dr. Vincenzo Raieli
Dr. Vittorio Sciruicchio
Dr. Andrea Santangelo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • migraine
  • pediatric migraine
  • migraine therapy
  • cranial autonomic symptoms
  • neuroimaging
  • aura
  • non-pharmacological therapies
  • comorbidity
  • neurophysiology

Published Papers (2 papers)

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16 pages, 1649 KiB  
Article
Gout and Migraines: Exploring the Complex Link in a 16-Year Longitudinal Study of the Korean Population
by Ho Suk Kang, Ji Hee Kim, Joo-Hee Kim, Woo Jin Bang, Hyo Geun Choi, Nan Young Kim, Ha Young Park, Kyung Chan Choi, Younghee Choi and Mi Jung Kwon
J. Clin. Med. 2024, 13(1), 138; https://doi.org/10.3390/jcm13010138 - 26 Dec 2023
Viewed by 943
Abstract
Despite the growing prevalence of gout and its associated health concerns as a chronic disorder, population-based studies on its link to migraines are scarce. We conducted a 16-year longitudinal study in a Korean population to investigate the relationship between gout and migraines, including [...] Read more.
Despite the growing prevalence of gout and its associated health concerns as a chronic disorder, population-based studies on its link to migraines are scarce. We conducted a 16-year longitudinal study in a Korean population to investigate the relationship between gout and migraines, including different subtypes. We enrolled 23,137 patients with gout and matched them with 92,548 controls based on age, sex, income, and residence. Using Cox proportional hazards models, we calculated hazard ratios to assess the likelihood of migraines while considering relevant factors. During the follow-up, 1000 gout patients and 3214 controls experienced migraines. After adjusting for various factors, including demographics, health-related variables, and weight categories, the gout group had a 1.26-fold higher likelihood of developing migraines compared to the group without gout. This association was particularly strong for migraines without aura, while it was not significant for migraines with aura. In summary, our study reveals a significant link between gout and migraines in the Korean population, emphasizing the complex relationship among chronic disorders, with a specific focus on migraine subtypes. Full article
(This article belongs to the Special Issue Migraines: Diagnosis and Treatment)
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Review

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10 pages, 617 KiB  
Review
Should We Rule out Celiac Disease in Recurrent Headache Disorders? A Review of the Literature
by Lorenzo Perilli, Samanta Carbone, Luca Franco Novelletto, Andrea Santangelo, Maria Rosaria Curcio, Federica Lotti and Salvatore Grosso
J. Clin. Med. 2024, 13(9), 2615; https://doi.org/10.3390/jcm13092615 - 29 Apr 2024
Viewed by 411
Abstract
Recurrent headaches, encompassing migraine and tension-type headaches, represent prevalent conditions affecting individuals across different age groups, exerting a substantial influence on daily functioning and quality of life. Headaches serve as common manifestations of underlying health issues. Among these, celiac disease, an autoimmune disorder [...] Read more.
Recurrent headaches, encompassing migraine and tension-type headaches, represent prevalent conditions affecting individuals across different age groups, exerting a substantial influence on daily functioning and quality of life. Headaches serve as common manifestations of underlying health issues. Among these, celiac disease, an autoimmune disorder activated by gluten consumption, has emerged as a noteworthy concern. Recent research indicates a correlation between celiac disease and heightened susceptibility to headaches, particularly migraines. Celiac disease (CD) is an immune-mediated systemic, widespread disorder presenting a heterogeneous constellation of symptoms with a relatively easy diagnosis and therapy. Among signs and symptoms exhibited in celiac disease patients, headache is one of the most common neurological issues addressed among both adults and children. Headache disorders and CD are highly prevalent in the general population; for this reason, any causal association between these conditions and the role of a gluten-free diet (GFD) has been debated. The aim of this manuscript is to review the current scientific literature regarding the potential association between CD and headaches and the beneficial effects of a GFD. Among the various authors, in our opinion, the current state of the evidence suggests a significant role for the early screening of CD during the initial diagnosis of recurrent headaches, either in adults or children. Full article
(This article belongs to the Special Issue Migraines: Diagnosis and Treatment)
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