Cardiovascular Diseases: From Basic Research to Clinical Application–2nd Edition

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1094

Special Issue Editors


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Guest Editor
Department of Preclinical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania
Interests: cardiovascular disease; pathophysiology; oxidative stress; inflammation; hemostasis; diabetes mellitus
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
1. Department of Pharmacy, Faculty of Medicine and Pharmacy, University of Oradea, 410028 Oradea, Romania
2. Doctoral School of Biomedical Sciences, University of Oradea, 410087 Oradea, Romania
Interests: pharmacology; alternative therapies; biochemistry; public health; therapeutics; One Health; sustainability in health; ecology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

With the first volume of this Special Issue being a great success (https://www.mdpi.com/journal/life/special_issues/0UO87783VR), we invite you to publish your research in the second volume.

Presently, cardiovascular disease (CVD) is the most prominent menace to human health. Because CVD is still the leading cause of death, research in this field is a critical task. Although recent decades have seen tremendous progress regarding the risk factors of CVD, the molecular basis of atherosclerosis, coronary revascularization and treatment of heart failure (these being only a few areas of research interest to be reminded), much remains to be done and the prospects are promising. In order to improve the quality and length of life for those at risk for CVD, research for better predictors of this disease and better means for prevention and treatment must be the target.

The purpose of this Special Issue is to identify several important advances in clinical and basic research in CVD that will provide the tools for further progress in the prevention and treatment of this disease. As artificial intelligence plays an increasingly important role in the prevention of CVD, it may be worth considering this aspect.

Therefore, it is our pleasure to cordially invite those of you with interest in CVD research and willing to be part of this Special Issue to publish papers that address novelties in both clinical and basic cardiovascular research. We encourage the submission of all types of manuscripts, including original studies, reviews and short communications.

Dr. Cristiana Bustea
Prof. Dr. Delia Mirela Tit
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • CVDs
  • risk factors
  • prevention
  • treatment
  • novelties in research
  • artificial intelligence

Published Papers (2 papers)

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Review

10 pages, 562 KiB  
Review
The Impact of Peri-Implant Diseases on the General Status of Patients with Cardiovascular Diseases: A Literature Review
by Ana Maria Hofer, Alexandra Dadarlat-Pop, Alexandru Mester, Bogdana Adriana Nasui, Monica Popa and Andrei Picos
Life 2024, 14(6), 665; https://doi.org/10.3390/life14060665 - 23 May 2024
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Abstract
Background and Objectives: The aim of this study is to connect peri-implantitis to cardiovascular diseases, following the association found between periodontitis and cardiovascular conditions in recent years. Materials and Methods: PubMed, Scopus, Web of Science online databases were searched up to June 2023, [...] Read more.
Background and Objectives: The aim of this study is to connect peri-implantitis to cardiovascular diseases, following the association found between periodontitis and cardiovascular conditions in recent years. Materials and Methods: PubMed, Scopus, Web of Science online databases were searched up to June 2023, with the exclusion criteria being research written in a language other than English. The MeSH search items were as follows: [“peri-implant health OR peri-implantitis OR peri-implant mucositis OR peri-implant disease”] AND [“cardiovascular diseases”]. Patient/population (P), intervention (I), comparison (C), outcome (O) framework questions were followed to identify the clinical evidence for the systematic review. Only clinical studies that used a control group to compare the relationship between cardiovascular diseases and peri-implantitis were selected. Results: A total of 118 studies were identified through electronic search of the keywords. After removing duplicates, there were 76 records to be screened. Upon exclusion of ineligible titles and abstracts, 27 studies remained for evaluation. Finally, 23 studies were excluded for not meeting the inclusion criteria, leaving 4 studies to be included in the qualitative analyses. Conclusions: This study found there is a linear association between mucosal/gingival inflammation and carotid intima–media thickness test (c-IMT) values. Peri-implant mucosal inflammation could be a contributor to the vascular disease burden of an individual; further specific clinical studies should be performed in order to demonstrate this connection. Full article
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20 pages, 2289 KiB  
Review
Role of Ectopic Olfactory Receptors in the Regulation of the Cardiovascular–Kidney–Metabolic Axis
by Mitchell R. Beito, Sadia Ashraf, Dorcas Odogwu and Romain Harmancey
Life 2024, 14(5), 548; https://doi.org/10.3390/life14050548 - 25 Apr 2024
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Abstract
Olfactory receptors (ORs) represent one of the largest yet least investigated families of G protein-coupled receptors in mammals. While initially believed to be functionally restricted to the detection and integration of odors at the olfactory epithelium, accumulating evidence points to a critical role [...] Read more.
Olfactory receptors (ORs) represent one of the largest yet least investigated families of G protein-coupled receptors in mammals. While initially believed to be functionally restricted to the detection and integration of odors at the olfactory epithelium, accumulating evidence points to a critical role for ectopically expressed ORs in the regulation of cellular homeostasis in extranasal tissues. This review aims to summarize the current state of knowledge on the expression and physiological functions of ectopic ORs in the cardiovascular system, kidneys, and primary metabolic organs and emphasizes how altered ectopic OR signaling in those tissues may impact cardiovascular–kidney–metabolic health. Full article
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