Biosynthesis of Marine Microbial Natural Products

A special issue of Marine Drugs (ISSN 1660-3397). This special issue belongs to the section "Marine Biotechnology Related to Drug Discovery or Production".

Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 748

Special Issue Editor

Special Issue Information

Dear Colleagues,

The field of biosynthesis of marine microbial natural products is a dynamic and interdisciplinary area of research at the intersection of marine biology, microbiology, organic chemistry, and pharmacology. It explores the intricate processes by which marine microbes, residing in vast and diverse aquatic ecosystems, synthesize a plethora of unique natural products with pharmaceutical potential. This Special Issue will focus on unravelling the biosynthetic pathways and mechanisms underlying these processes, thus contributing to microbial biodiscovery and the identification of new metabolites. By investigating theis phenomenon, we aim to deepen the understanding of the ecological roles, genetic regulation, and enzymatic transformations involved, holding great promise for drug discovery, biotechnology, and environmental conservation. In-depth topical review articles discussing marine metabolites will also be taken into consideration.

Dr. Zeinab Khalil
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural product biodiscovery
  • marine microbes
  • drug discovery
  • ecological roles
  • enzymatic pathways
  • metabolite identification
  • genetic regulation
  • biosynthesis of new metabolites
  • microbial biodiscovery

Published Papers (1 paper)

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Review

28 pages, 1219 KiB  
Review
Engineering Fatty Acid Biosynthesis in Microalgae: Recent Progress and Perspectives
by Yanhui Song, Fangzhong Wang, Lei Chen and Weiwen Zhang
Mar. Drugs 2024, 22(5), 216; https://doi.org/10.3390/md22050216 - 9 May 2024
Viewed by 582
Abstract
Microalgal lipids hold significant potential for the production of biodiesel and dietary supplements. To enhance their cost-effectiveness and commercial competitiveness, it is imperative to improve microalgal lipid productivity. Metabolic engineering that targets the key enzymes of the fatty acid synthesis pathway, along with [...] Read more.
Microalgal lipids hold significant potential for the production of biodiesel and dietary supplements. To enhance their cost-effectiveness and commercial competitiveness, it is imperative to improve microalgal lipid productivity. Metabolic engineering that targets the key enzymes of the fatty acid synthesis pathway, along with transcription factor engineering, are effective strategies for improving lipid productivity in microalgae. This review provides a summary of the advancements made in the past 5 years in engineering the fatty acid biosynthetic pathway in eukaryotic microalgae. Furthermore, this review offers insights into transcriptional regulatory mechanisms and transcription factor engineering aimed at enhancing lipid production in eukaryotic microalgae. Finally, the review discusses the challenges and future perspectives associated with utilizing microalgae for the efficient production of lipids. Full article
(This article belongs to the Special Issue Biosynthesis of Marine Microbial Natural Products)
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