Pharmaceutical Nanotechnology for Biomedical Applications: Current Advances and Future Prospects
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Nanochemistry".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 18993
Special Issue Editor
Interests: nanotechnology; ocular drug delivery; age-related macular degeneration treatment using functional nanoparticles; breast cancer treatment using nanotechnology; ovarian cancer treatment using nanotechnology; delivery of siRNA using nanoparticles; implantable drug delivery systems
Special Issue Information
Dear Colleagues,
Nanotechnology has attracted considerable attention due to its outstanding diversity in the biomedical applications. Nano-encapsulation of drugs modifies their physicochemical properties such as charges, size, and solubility, providing more effective treatment than conventional drug therapy, with fewer side effects. The use of nanoparticles offers many advantages, such as improving drugs’ penetration through biological membranes, enhancing drugs absorption and bioavailability, accumulating drugs at the target site, ability to incorporate small molecules and large biomacromolecules, enhancing drugs’ stability, and reducing their toxicity and cost. Various types of nanoparticles have been developed to date, each with different materials and properties, to be administered through various routes. Their small size enables them to escape the macrophages and to remain in systemic circulation for a longer time to reach the site of action via a passive targeting mechanism. Surface modulation with ligands permits a directed targeted mechanism (active targeting) and enhances nanoparticles’ intracellular transport through various endocytotic processes. In addition to drug delivery and targeting, nanotechnology has also been exploited in imaging and diagnose.
In this Special Issue, we invite researchers to contribute original research articles, as well as review articles that are related to nanotechnology in biomedical applications. We are particularly interested in research on current nanotechnology application in ocular, pulmonary, oral, and skin drug delivery. Nanotechnology for cancer treatment and its application in diagnosis and imaging are also of interest and focus in this issue.
Dr. Raida Al-Kassas
Guest Editor
Manuscript Submission Information
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Keywords
- Nanoparticles design
- Ocular delivery
- Cancer targeting
- Pulmonary delivery
- Skin delivery
- Oral delivery
- Nanoparticles for imaging
- Functionalized nanoparticles
- Nanoparticles for diagnosis