Vitamins and Human Health: 2nd Edition

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".

Deadline for manuscript submissions: 25 August 2024 | Viewed by 765

Special Issue Editor


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Guest Editor
1. Sports Medicine Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA
2. Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA
3. Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA
Interests: anterior cruciate ligament injury; osteoarthritis; cachexia; vitamin D; cytokines; systemic inflammation; precision nutrition
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Special Issue Information

Dear Colleagues,

Vitamins are essential compounds involved in fundamental functions of the body. Vitamins differ in physiological functions and are broadly classified as water-soluble or fat-soluble. The purpose of this Special Issue, “Vitamins and Human Health: 2nd Edition”, is to build upon the first edition by providing cutting-edge original research and review articles regarding the diverse properties of various vitamins in disease and healthy living conditions. This Special Issue will discuss the potential role of vitamins on health and disease etiology, progression, treatment, and the recovery from injury and/or surgery. Articles eloquently discussing the various or new determinants of endogenous vitamin levels in disease and non-disease related conditions are encouraged. Submissions discussing the influence of a vitamin or vitamins on physical performance and survival are welcome.

Dr. Tyler Barker
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • vitamin C
  • vitamin B complex
  • vitamin A
  • vitamin D
  • vitamin E

Published Papers (1 paper)

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Research

14 pages, 653 KiB  
Article
Vitamin K Status Based on K1, MK-4, MK-7, and Undercarboxylated Prothrombin Levels in Adolescent and Adult Patients with Cystic Fibrosis: A Cross-Sectional Study
by Patrycja Krzyżanowska-Jankowska, Jan Nowak, Marta Karaźniewicz-Łada, Małgorzata Jamka, Eva Klapkova, Szymon Kurek, Sławomira Drzymała-Czyż, Aleksandra Lisowska, Irena Wojsyk-Banaszak, Wojciech Skorupa, Jarosław Szydłowski, Richard Prusa and Jarosław Walkowiak
Nutrients 2024, 16(9), 1337; https://doi.org/10.3390/nu16091337 - 29 Apr 2024
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Abstract
The available evidence on vitamin K status in cystic fibrosis (CF) is scarce, lacking data on vitamin K2 (menaquinones—MK). Therefore, we assessed vitamin K1, MK-4 and MK-7 concentrations (LC-MS/MS) in 63 pancreatic insufficient and modulator naïve CF patients, and compared to 61 healthy [...] Read more.
The available evidence on vitamin K status in cystic fibrosis (CF) is scarce, lacking data on vitamin K2 (menaquinones—MK). Therefore, we assessed vitamin K1, MK-4 and MK-7 concentrations (LC-MS/MS) in 63 pancreatic insufficient and modulator naïve CF patients, and compared to 61 healthy subjects (HS). Vitamin K1 levels did not differ between studied groups. MK-4 concentrations were higher (median <1st–3rd quartile>: 0.778 <0.589–1.086> vs. 0.349 <0.256–0.469>, p < 0.0001) and MK-7 levels lower (0.150 <0.094–0.259> vs. 0.231 <0.191–0.315>, p = 0.0007) in CF patients than in HS. MK-7 concentrations were higher in CF patients receiving K1 and MK-7 supplementation than in those receiving vitamin K1 alone or no supplementation. Moreover, vitamin K1 concentrations depended on the supplementation regime. Based on multivariate logistic regression analysis, we have found that MK-7 supplementation dose has been the only predictive factor for MK-7 levels. In conclusion, vitamin K1 levels in CF are low if not currently supplemented. MK-4 concentrations in CF patients supplemented with large doses of vitamin K1 are higher than in HS. MK-7 levels in CF subjects not receiving MK-7 supplementation, with no regard to vitamin K1 supplementation, are low. There do not seem to be any good clinical predictive factors for vitamin K status. Full article
(This article belongs to the Special Issue Vitamins and Human Health: 2nd Edition)
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