The Role of the Gut Microbiome in Health and Disease
A special issue of Pathogens (ISSN 2076-0817).
Deadline for manuscript submissions: closed (20 May 2024) | Viewed by 24746
Special Issue Editors
Interests: gut microbiome; microbially driven GI cancer; gastric cancer; inflammatory bowel disease; helicobacter pylori infection
Interests: microbiome; inflammation; infectious diseases; healthy microbiome; mental health and neuroscience; women and children’s health; and natural therapies; sex-differences in immune responses
Special Issue Information
Dear Colleagues,
Our understanding of the impact of microbes on their human hosts is only just emerging. These microbial communities have coevolved with us, forming astonishing ‘symbiotic relationships’ with our bodies that are largely responsible for our overall health. Our intestinal lining usually forms tight junctions that control absorption into the bloodstream. However, when this barrier becomes leaky, microbes and their metabolites can enter the bloodstream and trigger widespread inflammation and changes in the gut microbiome, known as gut dysbiosis. Gut dysbiosis has been associated with diseases such as autism, obesity, diabetes, cancer, inflammatory bowel disease, and dementia. The associations between the gut microbiome and the pathogenesis of disease have positioned the gut microbiome as a potential novel target for therapeutics.
This Special Issue focuses on the complex interplay between the gut microbiome and the balance between health and disease. You are invited to submit state-of the art reviews as well as original research articles on the role of microbiota found in disease, across multiple systems including but not limited to hepatobiliary, cardiovascular and urogynecological. We welcome research on all aspects of the gut microbiome in health, particularly works that demonstrate a role of gut microbiota in the pathogenesis of disease, with a focus on host–microbiota interactions, or research on the microbiome regarding its potential to yield biomarkers or therapeutics in disease.
Prof. Dr. Emad M. El-Omar
Dr. Fatima El-Assaad
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- microbiome
- gut microbiome
- intestinal permeability
- bacteria
- health
- dysbiosis