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Alkaloids: Chemical Structures with Pharmaceutical Potential
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Alkaloids: Chemical Structures with Pharmaceutical Potential

A special issue of Plants (ISSN 2223-7747). This special issue belongs to the section "Phytochemistry".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 701

Special Issue Editors

Prof. Dr. Jaume Bastida

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Guest Editor
Group of Natural Products, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain
Interests: plant alkaloids; structural elucidation; NMR; MS
Special Issues, Collections and Topics in MDPI journals
Dr. Luciana R. Tallini

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Guest Editor
Group of Natural Products, Faculty of Pharmacy and Food Sciences, University of Barcelona, Av. Joan XXIII, 27-31, 08028 Barcelona, Spain
Interests: alkaloids; biological activities; GC-MS
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Alkaloids are natural products obtained from a wide range of organisms, mainly plants. They have attracted the attention of scientists from different research backgrounds due to their chemical diversity and notable biological and pharmacological properties, as well as their potential to be applied in therapeutic settings.

In this Special Issue, we invite manuscript submissions on alkaloid natural sources and their chemical identification/characterization, as well as on their biological properties and pharmacological potential.

Prof. Dr. Jaume Bastida
Dr. Luciana R. Tallini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Plants is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • alkaloids
  • extraction and isolation
  • chemical profile
  • structural elucidation
  • biological activities
  • pharmacological potential

Published Papers (1 paper)

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Review

27 pages, 1109 KiB  
Review
Health Benefits of the Alkaloids from Lobeira (Solanum lycocarpum St. Hill): A Comprehensive Review
by Felipe Tecchio Borsoi, Glaucia Maria Pastore and Henrique Silvano Arruda
Plants 2024, 13(10), 1396; https://doi.org/10.3390/plants13101396 - 17 May 2024
Viewed by 530
Abstract
Solanum is the largest genus within the Solanaceae family and has garnered considerable attention in chemical and biological investigations over the past 30 years. In this context, lobeira or “fruta-do-lobo” (Solanum lycocarpum St. Hill), a species predominantly found in the Brazilian Cerrado, [...] Read more.
Solanum is the largest genus within the Solanaceae family and has garnered considerable attention in chemical and biological investigations over the past 30 years. In this context, lobeira or “fruta-do-lobo” (Solanum lycocarpum St. Hill), a species predominantly found in the Brazilian Cerrado, stands out. Beyond the interesting nutritional composition of the fruits, various parts of the lobeira plant have been used in folk medicine as hypoglycemic, sedative, diuretic, antiepileptic, and antispasmodic agents. These health-beneficial effects have been correlated with various bioactive compounds found in the plant, particularly alkaloids. In this review, we summarize the alkaloid composition of the lobeira plant and its biological activities that have been reported in the scientific literature in the last decades. The compiled data showed that lobeira plants and fruits contain a wide range of alkaloids, with steroidal glycoalkaloid solamargine and solasonine being the major ones. These alkaloids, but not limited to them, contribute to different biological activities verified in alkaloid-rich extracts/fractions from the lobeira, including antioxidant, anti-inflammatory, anticancer, antigenotoxic, antidiabetic, antinociceptive, and antiparasitic effects. Despite the encouraging results, additional research, especially toxicological, pre-clinical, and clinical trials, is essential to validate these human health benefits and ensure consumers’ safety and well-being. Full article
(This article belongs to the Special Issue Alkaloids: Chemical Structures with Pharmaceutical Potential)
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