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Terahertz Spectroscopic Sensing and Imaging Technology for Biomedicine

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: 25 August 2024 | Viewed by 1359

Special Issue Editors

School of Precise Instrument and Opto-Electronics, Tianjin University, Tianjin 300072, China
Interests: terehertz photonics; terahertz spectroscopy and imaging; nonlinear optics; all solid-state laser
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Guest Editor
Research Center of Super-Resolution Optics, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing 400714, China
Interests: terahertz near-field; terahertz bio-detection; terahertz devices

Special Issue Information

Dear Colleagues,

Terahertz spectroscopic sensing and imaging techniques based on optics and photonics technology open a new realm for biomedical applications, ranging from basic science investigations to real life. The focus of this issue is to provide an interdisciplinary forum for the current state-of-the-art developments in both fundamental and technological aspects of terahertz spectroscopic sensing and imaging for biomedical applications, including the recent progress and trends in terahertz source, sensing, spectroscopy, imaging, and their applications. The techniques suitable for unexplored regions are particularly encouraged. Both original research and review articles are accepted. Topics include but are not limited to:

  • Terahertz source;
  • Terahertz spectroscopic sensing;
  • Terahertz imaging;
  • Terahertz application in biomedicine;
  • Data processing for terahertz spectroscopy and imaging.

Dr. Yuye Wang
Dr. Huabin Wang
Guest Editors

Manuscript Submission Information

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Published Papers (1 paper)

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Research

11 pages, 2671 KiB  
Article
Calcium Imaging Characterize the Neurobiological Effect of Terahertz Radiation in Zebrafish Larvae
by Xin Song, Haibin Li, Xiuyun Liu, Meijun Pang and Yuye Wang
Sensors 2023, 23(18), 7689; https://doi.org/10.3390/s23187689 - 6 Sep 2023
Viewed by 914
Abstract
(1) Objective: To explore the neurobiological effects of terahertz (THz) radiation on zebrafish larvae using calcium (Ca2+) imaging technology. (2) Methods: Zebrafish larvae at 7 days post fertilization (dpf) were exposed to THz radiation for 10 or 20 min; the frequency [...] Read more.
(1) Objective: To explore the neurobiological effects of terahertz (THz) radiation on zebrafish larvae using calcium (Ca2+) imaging technology. (2) Methods: Zebrafish larvae at 7 days post fertilization (dpf) were exposed to THz radiation for 10 or 20 min; the frequency was 2.52 THz and the amplitude 50 mW/cm2. The behavioral experiments, neural Ca2+ imaging, and quantitative polymerase chain reaction (qPCR) of the dopamine-related genes were conducted following the irradiation. (3) Results: Compared with the control group, the behavioral experiments demonstrated that THz radiation significantly increased the distance travelled and speed of zebrafish larvae. In addition, the maximum acceleration and motion frequency were elevated in the 20 min radiation group. The neural Ca2+ imaging results indicated a substantial increase in zebrafish neuronal activity. qPCR experiments revealed a significant upregulation of dopamine-related genes, such as drd2b, drd4a, slc6a3 and th. (4) Conclusion: THz radiation (2.52 THz, 50 mW/cm2, 20 min) upregulated dopamine-related genes and significantly enhanced neuronal excitability, and the neurobiological effect of THz radiation can be visualized using neural Ca2+ imaging in vivo. Full article
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