Traditional and Emerging Pollutants: Human Exposure Profiles and Health Effects

A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Human Toxicology and Epidemiology".

Deadline for manuscript submissions: 19 July 2024 | Viewed by 668

Special Issue Editor


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Guest Editor
Department of Public Health and Preventive Medicine, School of Medicine, Jinan University, Guangzhou 510632, China
Interests: environmental exposure and fetal development; environmental exposure and reproductive health
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Studies have shown that the number of high-volume toxic and hazardous chemicals, which are persistent, bioaccumulative, carcinogenic, mutagenic, and have reproductive toxicity, has now reached more than 600. These chemicals can enter the environment at all stages of production, processing, use, and consumption, posing potential environmental and health risks.

Toxic and hazardous chemicals are the main sources of emerging contaminants (ECs), and there are currently four main categories of ECs that we are concerned about: persistent organic pollutants (POPs), endocrine disruptors, antibiotics, and microplastics. They are considered to be hot research topics in the future. Humans can be exposed to them either due to their occupations or through dietary and environmental exposure (water, soil, and air), and it is becoming increasingly difficult to avoid exposure to traditional and emerging pollutants. However, the paucity of studies on ECs and the inconsistency of their findings remain controversial. The aim of this Special Issue is to identify reliable evidence showing the effects of compound exposure to traditional and emerging pollutants on the health of adult male and female, as well as on fetus growth and development.

Therefore, in this Special Issue, “Traditional and Emerging Pollutants: Human Exposure Profiles and Health Effects”, we accept excellent research that addresses one or more of the following topics, among others:

  • Emerging pollutants;
  • Human exposure profiles;
  • Mixed exposure;
  • Health damage.

Prof. Dr. Pan Yang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • exposure assessment
  • emerging pollutants
  • mixed exposure
  • health effect and damage
  • epigenomics

Published Papers (1 paper)

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Research

13 pages, 851 KiB  
Article
Temporal Trend of Serum Perfluorooctanoic Acid and Perfluorooctane Sulfonic Acid among U.S. Adults with or without Comorbidities in NHANES 1999–2018
by Jinhua Pan, Changping Ouyang, Shengze Zhou, Xuemei Wang, Heming Liu, Jia Zhang, Xiao Wang, Xiaoru Shi, Aimin Yang and Xiaobin Hu
Toxics 2024, 12(5), 314; https://doi.org/10.3390/toxics12050314 - 26 Apr 2024
Viewed by 521
Abstract
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are associated with adverse health effects. This study examined the trend of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) levels in individuals with and without pre-existing comorbidities. We analyzed the characteristics of 13,887 participants across nine U.S. [...] Read more.
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are associated with adverse health effects. This study examined the trend of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) levels in individuals with and without pre-existing comorbidities. We analyzed the characteristics of 13,887 participants across nine U.S. NHANES cycles (1999–2000 to 2017–2018) and calculated the geometric mean (GM) of PFOA and PFOS levels, standardized by sex and age. A joinpoint regression model was used to analyze the temporal trends of serum PFOA and PFOS levels. We observed declining PFOA and PFOS serum levels among adults in NHANES from 1999–2000 to 2017–2018. Serum PFOA and PFOS concentrations were higher in men, smokers, and individuals with pre-existing CKD, hyperlipidemia, CVD, and cancer. We observed faster decline rates in PFOA levels among individuals with diabetes and CKD and faster decline rates in PFOS levels among individuals with diabetes and those without CKD. This study provided evidence of varying levels and changing trends of PFOA and PFOS between groups with and without established chronic disease, highlighting the role of environmental chemicals in the onset and development of chronic diseases. Full article
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