New Trends in Hepatocellular Carcinoma: Artificial Intelligence, Robotics and Innovative Treatments

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Methods and Technologies Development".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 376

Special Issue Editor


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Guest Editor
Service Chirurgie Digestive et Transplantation Hépatique, Hôpital Trousseau CHU, 37170 Tours, France
Interests: hepatocellular carcinoma; liver transplantation; robotic surgery

Special Issue Information

Dear Colleagues,

Hepatocellular carcinoma is a worldwide issue, and treatment has rapidly evolved in the recent years. Its prevalence and aetiology vary in different countries, but the incidence is increasing worldwide. Treatment and strategies are complex, with a wide range of medical and surgical solutions often combined, but frequently used differently and in different fashions according to countries, regions, hospitals, and even medical teams.  These variations reflect the combined presence of a complex neoplastic disease almost constantly associated with cirrhosis, necessitating a single strategy to treat two diseases at a time. Evolutions in immunotherapy and chemotherapy, technical innovations such as the R.A.P.I.D. technique in liver transplantation, the use of indocyanine green during liver resection, the progressive widespread of robotics, and the emerging role of artificial intelligence are changing the standard paradigms and opening new frontiers to future developments. The real benefits of these innovations are still under investigation, but precision medicine and precision surgery has become a cornerstone concept in the management of the disease. In this Special Issue, we aim to present the most recent advances and innovations in the management of hepatocellular carcinoma, in order to understand the most important trends and future directions.

Dr. Emanuele Felli
Guest Editor

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Keywords

  • hepatocellular carcinoma
  • innovations
  • future trends
  • robotics
  • artificial intelligence

Published Papers (1 paper)

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Research

10 pages, 352 KiB  
Article
Assessment of Segmentary Hypertrophy of Future Remnant Liver after Liver Venous Deprivation: A Single-Center Study
by Bader Al Taweel, Gianluca Cassese, Salah Khayat, Maurice Chazal, Francis Navarro, Boris Guiu and Fabrizio Panaro
Cancers 2024, 16(11), 1982; https://doi.org/10.3390/cancers16111982 - 23 May 2024
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Abstract
Background: Liver venous deprivation (LVD) is a recent radiological technique that has shown promising results on Future Remnant Liver (FRL) hypertrophy. The aim of this retrospective study is to compare the segmentary hypertrophy of the FRL after LVD and after portal vein [...] Read more.
Background: Liver venous deprivation (LVD) is a recent radiological technique that has shown promising results on Future Remnant Liver (FRL) hypertrophy. The aim of this retrospective study is to compare the segmentary hypertrophy of the FRL after LVD and after portal vein embolization (PVE). Methods: Patients undergoing PVE or LVD between April 2015 and April 2020 were included. The segmentary volumes (seg 4, seg2+3 and seg1) were assessed before and after the radiological procedure. Results: Forty-four patients were included: 26 undergoing PVE, 10 LVD and 8 eLVD. Volume gain of both segment 1 and segments 2+3 was significantly higher after LVD and eLVD than after PVE (segment 1: 27.33 ± 35.37 after PVE vs. 38.73% ± 13.47 after LVD and 79.13% ± 41.23 after eLVD, p = 0.0080; segments 2+3: 40.73% ± 40.53 after PVE vs. 45.02% ± 21.53 after LVD and 85.49% ± 45.51 after eLVD, p = 0.0137), while this was not true for segment 4. FRL hypertrophy was confirmed to be higher after LVD and eLVD than after PVE (33.53% ± 21.22 vs. 68.63% ± 42.03 vs. 28.11% ± 28.33, respectively, p = 0.0280). Conclusions: LVD and eLVD may induce greater hypertrophy of segment 1 and segments 2+3 when compared to PVE. Full article
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