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Review Special Issue: Recent Advances in Personalized Medicine
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Review Special Issue: Recent Advances in Personalized Medicine

A special issue of Journal of Personalized Medicine (ISSN 2075-4426).

Deadline for manuscript submissions: 30 September 2024 | Viewed by 408

Special Issue Editor

Prof. Dr. David Alan Rizzieri

E-Mail Website
Guest Editor
1. Novant Health Cancer Institute, Winston-Salem, NC 27103, USA
2. Division of Hematologic Malignancies and Cellular Therapy, Duke University, Durham, NC 27710, USA
Interests: hematopoietic blood or stem cell transplant; leukemia; lymphoma; malignant hematology; myelodysplastic syndromes

Special Issue Information

Dear Colleagues,

This Special Issue is a compilation of review articles that highlight the latest research findings and advancements in the field of personalized medicine. This series focuses on providing a comprehensive overview of various topics, including, but not limited to, diagnostic techniques, therapeutic interventions, emerging trends in biomarkers, etc. By featuring expert reviews, this Special Issue offers valuable insights and critical analyses of the current state of research in personalized medicine.

Prof. Dr. David Alan Rizzieri
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • personalized medicine
  • omics
  • informatics
  • pharmacogenetics
  • clinical medicine
  • cell
  • organism physiology
  • epidemiology
  • mechanisms of diseases
  • methodology
  • drug and device discovery
  • personalized therapy
  • drug delivery
  • evidence-based medicine
  • regenerative medicine and therapeutics
  • epigenetic therapy
  • sex-, gender- and hormone-based medicine
  • disease biomarker
  • personalized critical care
  • molecular targeted therapy

Published Papers (1 paper)

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Review

11 pages, 1629 KiB  
Review
Red-Haired People’s Altered Responsiveness to Pain, Analgesics, and Hypnotics: Myth or Fact?—A Narrative Review
by Annelie Augustinsson, Elisabeth Franze, Martina Almqvist, Margareta Warrén Stomberg, Carina Sjöberg and Pether Jildenstål
J. Pers. Med. 2024, 14(6), 583; https://doi.org/10.3390/jpm14060583 - 29 May 2024
Viewed by 221
Abstract
Red hair has been linked to altered sensitivity to pain, analgesics, and hypnotics. This alteration may be impacted by variants in the melanocortin-1 receptor (MC1R) gene, which are mainly found in redheads. The aim of this narrative review was to explore [...] Read more.
Red hair has been linked to altered sensitivity to pain, analgesics, and hypnotics. This alteration may be impacted by variants in the melanocortin-1 receptor (MC1R) gene, which are mainly found in redheads. The aim of this narrative review was to explore and present the current state of knowledge on red hair and its plausible associations with altered responsiveness to pain, analgesics, and hypnotics. Structured searches in the PubMed, CINAHL Complete, and Scopus electronic databases were conducted. Evidence suggests that women with red hair have an increased sensitivity to pain. Conversely, data also indicate a higher pain tolerance in homozygous carriers of MC1R variant alleles. Varied responses to analgesia have been reported, with both increased analgesic responsiveness in homozygous carriers of MC1R variant alleles and less analgesia in redheads. Data indicate an increased need for hypnotics in redheads. However, failed attempts to find statistical associations between red hair and altered responsiveness to hypnotics are also evident. Even though there seems to be an association between red hair and an altered responsiveness to pain, analgesics, and/or hypnotics, the results of this narrative review are inconclusive. Further research studies with larger populations and MC1R testing are needed. Full article
(This article belongs to the Special Issue Review Special Issue: Recent Advances in Personalized Medicine)
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