Vitamins and Human Health: 2nd Edition

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Micronutrients and Human Health".

Deadline for manuscript submissions: 25 August 2024 | Viewed by 1674

Special Issue Editor


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Guest Editor
1. Sports Medicine Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USA
2. Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA
3. Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT, USA
Interests: anterior cruciate ligament injury; osteoarthritis; cachexia; vitamin D; cytokines; systemic inflammation; precision nutrition
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Special Issue Information

Dear Colleagues,

Vitamins are essential compounds involved in fundamental functions of the body. Vitamins differ in physiological functions and are broadly classified as water-soluble or fat-soluble. The purpose of this Special Issue, “Vitamins and Human Health: 2nd Edition”, is to build upon the first edition by providing cutting-edge original research and review articles regarding the diverse properties of various vitamins in disease and healthy living conditions. This Special Issue will discuss the potential role of vitamins on health and disease etiology, progression, treatment, and the recovery from injury and/or surgery. Articles eloquently discussing the various or new determinants of endogenous vitamin levels in disease and non-disease related conditions are encouraged. Submissions discussing the influence of a vitamin or vitamins on physical performance and survival are welcome.

Dr. Tyler Barker
Guest Editor

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Keywords

  • vitamin C
  • vitamin B complex
  • vitamin A
  • vitamin D
  • vitamin E

Published Papers (2 papers)

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Research

13 pages, 418 KiB  
Article
The Influence of Vitamin D Levels on Dental Caries: A Retrospective Study of the United States Population
by Man Hung, Himani Patel, Samantha Lee, Justin Nguyen and Amir Mohajeri
Nutrients 2024, 16(11), 1572; https://doi.org/10.3390/nu16111572 - 22 May 2024
Viewed by 737
Abstract
(1) Background: This study examines vitamin D’s impact on dental caries to inform prevention strategies, given its critical role in bone and calcium regulation, vital for dental health. (2) Methods: Data from 18,683 participants of the National Health and Nutrition Examination Survey (NHANES) [...] Read more.
(1) Background: This study examines vitamin D’s impact on dental caries to inform prevention strategies, given its critical role in bone and calcium regulation, vital for dental health. (2) Methods: Data from 18,683 participants of the National Health and Nutrition Examination Survey (NHANES) 2011–2016 were analyzed. NHANES collects U.S. population data through interviews, physical exams, and tests, including vitamin D levels and dental health assessed using both the decayed, missing, and filled teeth (DMFT) index and the presence of untreated dental caries. Vitamin D levels were measured according to serum 25(OH)D concentrations, and the analyses adjusted for confounders such as body mass index (BMI) and socioeconomic status (SES) using Chi-square, Mann–Whitney U, Kruskal–Wallis tests, as well as logistic and Poisson regression. (3) Results: This study found a mean DMFT score of 7.36 and a 33.2% prevalence of untreated dental caries. A higher caries prevalence was correlated with a lower SES (p < 0.001), the male gender (p < 0.001), and a higher BMI (p < 0.001). Severe vitamin D deficiency (<25 nmol/L) doubled the risk of dental caries, with odds ratios of 2.261 and 1.953 after adjusting for demographic factors and BMI. (4) Conclusions: Our study confirms a significant relationship between low vitamin D levels and an increased risk of dental caries nationwide, even after accounting for sociodemographic factors, emphasizing the importance of maintaining sufficient vitamin D levels for preventing caries. Full article
(This article belongs to the Special Issue Vitamins and Human Health: 2nd Edition)
14 pages, 653 KiB  
Article
Vitamin K Status Based on K1, MK-4, MK-7, and Undercarboxylated Prothrombin Levels in Adolescent and Adult Patients with Cystic Fibrosis: A Cross-Sectional Study
by Patrycja Krzyżanowska-Jankowska, Jan Nowak, Marta Karaźniewicz-Łada, Małgorzata Jamka, Eva Klapkova, Szymon Kurek, Sławomira Drzymała-Czyż, Aleksandra Lisowska, Irena Wojsyk-Banaszak, Wojciech Skorupa, Jarosław Szydłowski, Richard Prusa and Jarosław Walkowiak
Nutrients 2024, 16(9), 1337; https://doi.org/10.3390/nu16091337 - 29 Apr 2024
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Abstract
The available evidence on vitamin K status in cystic fibrosis (CF) is scarce, lacking data on vitamin K2 (menaquinones—MK). Therefore, we assessed vitamin K1, MK-4 and MK-7 concentrations (LC-MS/MS) in 63 pancreatic insufficient and modulator naïve CF patients, and compared to 61 healthy [...] Read more.
The available evidence on vitamin K status in cystic fibrosis (CF) is scarce, lacking data on vitamin K2 (menaquinones—MK). Therefore, we assessed vitamin K1, MK-4 and MK-7 concentrations (LC-MS/MS) in 63 pancreatic insufficient and modulator naïve CF patients, and compared to 61 healthy subjects (HS). Vitamin K1 levels did not differ between studied groups. MK-4 concentrations were higher (median <1st–3rd quartile>: 0.778 <0.589–1.086> vs. 0.349 <0.256–0.469>, p < 0.0001) and MK-7 levels lower (0.150 <0.094–0.259> vs. 0.231 <0.191–0.315>, p = 0.0007) in CF patients than in HS. MK-7 concentrations were higher in CF patients receiving K1 and MK-7 supplementation than in those receiving vitamin K1 alone or no supplementation. Moreover, vitamin K1 concentrations depended on the supplementation regime. Based on multivariate logistic regression analysis, we have found that MK-7 supplementation dose has been the only predictive factor for MK-7 levels. In conclusion, vitamin K1 levels in CF are low if not currently supplemented. MK-4 concentrations in CF patients supplemented with large doses of vitamin K1 are higher than in HS. MK-7 levels in CF subjects not receiving MK-7 supplementation, with no regard to vitamin K1 supplementation, are low. There do not seem to be any good clinical predictive factors for vitamin K status. Full article
(This article belongs to the Special Issue Vitamins and Human Health: 2nd Edition)
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