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Molecular Pharmacology

A section of Current Issues in Molecular Biology (ISSN 1467-3045).

Section Information

Receptor Theory and Drug Binding

  • Receptors and Biomolecules: Protein interactions and binding specifics.
  • Agonists and Antagonists: Analysis of antagonists and allosteric modulators.
  • Affinity and Efficacy: Evaluation of drug affinity, efficacy, and dose–response relationships.

Signal Transduction Pathways

  • Pharmacology Basics: Study of transmitters, protein synthesis, and release.
  • Cellular Cascades: Intracellular pathways involving G protein-coupled receptors (GPCRs), ion channels, and second messengers.

Pharmacogenomics and Personalized Medicine

  • Genetic Impact: How genetic makeup affects individual drug response.
  • Metabolic Aberrations: Genetic factors changing drug metabolism and therapeutic efficacy.
  • Design Strategies: Using personal genetic information for drug design.

Drug Discovery and Design

  • Discovery Methods: Recognition processes, molecular toxicology, and design.
  • Structural Approaches: Structure-based drug design and high-throughput screening assays.

Mechanisms of Drug Action and Metabolism

  • Molecular Characteristics: Biochemical and biophysical properties affecting biological macromolecules.
  • Enzyme Kinetics: Biotransformation pathways and molecular toxicology.

AI Approaches in Personalized Medicine

  • Concept Focus: Core concepts and algorithms for new results in AI-based drug design.
  • Exclusions: Programming-related topics are omitted from publication scope.

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Special Issues

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Papers Published

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