Relationship between Periodontal Disease and Systemic Disease

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 733

Special Issue Editor


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Guest Editor
Department of Dental Hygiene, Dongnam Health University, 50 Cheoncheon-ro 74-beon-gil, Jangan-gu, Suwon 16328, Republic of Korea
Interests: periodontitis; periodontal disease; systemic disease; periodontal–systemic interactions

Special Issue Information

Dear Colleagues,

As a symptom of chronic bacterial infection, periodontal disease has a high prevalence rate, which not only endangers oral health but also has a close relationship with systemic diseases. In the past few decades, many studies have confirmed that periodontal disease is related to diabetes, cardiovascular and cerebrovascular diseases, rheumatoid arthritis, respiratory diseases, etc. Despite significant progress in the field, given that periodontitis is characteristic of different classes of disease, it is necessary to conduct in-depth studies on the pathogenesis of periodontal disease, the relationship between periodontal disease and other unrelated diseases, and the specific biological mechanisms of the interaction between periodontitis and systemic diseases. The purpose of this Special Issue is to explore the latest knowledge in the field of research on the association between periodontal disease and systemic disease. We welcome submissions of original research articles and review papers, including studies on the etiology, diagnosis, effects, treatment, and interactions of periodontitis.

Dr. Hye-Sun Shin
Guest Editor

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Published Papers (1 paper)

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Review

13 pages, 256 KiB  
Review
Unlocking the Future of Periodontal Regeneration: An Interdisciplinary Approach to Tissue Engineering and Advanced Therapeutics
by Tsung-Hsi Huang, Jui-Yi Chen, Wei-Hsin Suo, Wen-Rou Shao, Chih-Ying Huang, Ming-Tse Li, Yu-Ying Li, Yuan-Hong Li, En-Lun Liang, Yu-Hsu Chen and I-Ta Lee
Biomedicines 2024, 12(5), 1090; https://doi.org/10.3390/biomedicines12051090 - 14 May 2024
Viewed by 366
Abstract
Periodontal defects present a significant challenge in dentistry, necessitating innovative solutions for comprehensive regeneration. Traditional restoration methods have inherent limitations in achieving complete and functional periodontal tissue reconstruction. Tissue engineering, a multidisciplinary approach integrating cells, biomaterials, and bioactive factors, holds tremendous promise in [...] Read more.
Periodontal defects present a significant challenge in dentistry, necessitating innovative solutions for comprehensive regeneration. Traditional restoration methods have inherent limitations in achieving complete and functional periodontal tissue reconstruction. Tissue engineering, a multidisciplinary approach integrating cells, biomaterials, and bioactive factors, holds tremendous promise in addressing this challenge. Central to tissue engineering strategies are scaffolds, pivotal in supporting cell behavior and orchestrating tissue regeneration. Natural and synthetic materials have been extensively explored, each offering unique advantages in terms of biocompatibility and tunable properties. The integration of growth factors and stem cells further amplifies the regenerative potential, contributing to enhanced tissue healing and functional restoration. Despite significant progress, challenges persist. Achieving the seamless integration of regenerated tissues, establishing proper vascularization, and developing biomimetic scaffolds that faithfully replicate the natural periodontal environment are ongoing research endeavors. Collaborative efforts across diverse scientific disciplines are essential to overcoming these hurdles. This comprehensive review underscores the critical need for continued research and development in tissue engineering strategies for periodontal regeneration. By addressing current challenges and fostering interdisciplinary collaborations, we can unlock the full regenerative potential, paving the way for transformative advancements in periodontal care. This research not only enhances our understanding of periodontal tissues but also offers innovative approaches that can revolutionize dental therapies, improving patient outcomes and reshaping the future of periodontal treatments. Full article
(This article belongs to the Special Issue Relationship between Periodontal Disease and Systemic Disease)
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