Effects of Plant Extracts on Human Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: 25 October 2024 | Viewed by 367

Special Issue Editors


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Guest Editor
Institute of Cellular Bioelectricity (IBIOCEL): Science & Health, Departament of Biochemistry, Center of Biological Sciences, Campus Trindade, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil
Interests: natural compounds; diabetes; infertility; cancer; central nervous system diseases; chronic diseases; medicinal plants; pain and analgesia
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Guest Editor
Departamento de Farmácia, Facultad de Ciencias, Universidad Nacional de Colombia, Cra. 30 45-03, Bogotá 111321, DC, Colombia
Interests: drug delivery; pharmacokinetics; microparticles; nanoparticles; self-emulsifying delivery; extracts standardization, bioactive compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to announce a Special Issue titled "Effects of Plant Extracts on Human Health" in Nutrients. This issue aims to explore the diverse impacts of plant extracts on human health, spanning from their nutritional value to their potential therapeutic effects/nutraceuticals.

We invite researchers, scientists, and experts to contribute their original research and reviews to this Special Issue. Submissions may include, but are not limited to, studies investigating:

The bioactive compounds present in plant extracts;

The mechanisms underlying the health effects of plant extracts;

The role of plant extracts in preventing or treating various health conditions;

The potential synergistic effects of combining different plant extracts;

The impact of processing and preparation methods on the bioavailability of plant extract compounds;

The utilization of plant extracts in functional foods and nutraceuticals.

We encourage submissions that utilize diverse methodologies, including in vitro and in vivo studies, clinical trials, and meta-analyses, to provide comprehensive insights into the effects of plant extracts on human health.

We look forward to receiving your contributions and to the collective advancement of knowledge in this important area of research.

Prof. Dr. Fátima Regina Mena Barreto Silva
Prof. Dr. Diana Marcela Aragon Novoa
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant extracts
  • human health
  • bioactive compounds
  • therapeutic effects
  • nutraceuticals

Published Papers (1 paper)

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Research

14 pages, 2167 KiB  
Article
Antidiabetic Effect of Passiflora ligularis Leaves in High Fat-Diet/Streptozotocin-Induced Diabetic Mice
by Diana P. Rey, Sandra M. Echeverry, Ivonne H. Valderrama, Ingrid A. Rodriguez, Luis F. Ospina, Fatima Regina Mena Barreto Silva and Marcela Aragón
Nutrients 2024, 16(11), 1669; https://doi.org/10.3390/nu16111669 - 29 May 2024
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Abstract
Type 2 diabetes mellitus (T2DM) is a major global public health concern, prompting the ongoing search for new treatment options. Medicinal plants have emerged as one such alternative. Our objective was to evaluate the antidiabetic effect of an extract from the leaves of [...] Read more.
Type 2 diabetes mellitus (T2DM) is a major global public health concern, prompting the ongoing search for new treatment options. Medicinal plants have emerged as one such alternative. Our objective was to evaluate the antidiabetic effect of an extract from the leaves of Passiflora ligularis (P. ligularis). For this purpose, T2DM was first induced in mice using a high-fat diet and low doses of streptozotocin. Subsequently, an aqueous extract or an ethanolic extract of P. ligularis leaves was administered for 21 days. The following relevant results were found: fasting blood glucose levels were reduced by up to 41%, and by 29% after an oral glucose overload. The homeostasis model assessment of insulin resistance (HOMA-IR) was reduced by 59%. Histopathologically, better preservation of pancreatic tissue was observed. Regarding oxidative stress parameters, there was an increase of up to 48% in superoxide dismutase (SOD), an increase in catalase (CAT) activity by 35% to 80%, and a decrease in lipid peroxidation (MDA) by 35% to 80% in the liver, kidney, or pancreas. Lastly, regarding the lipid profile, triglycerides (TG) were reduced by up to 30%, total cholesterol (TC) by 35%, and low-density lipoproteins (LDL) by up to 32%, while treatments increased high-density lipoproteins (HDL) by up to 35%. With all the above, we can conclude that P. ligularis leaves showed antihyperglycemic, hypolipidemic, and antioxidant effects, making this species promising for the treatment of T2DM. Full article
(This article belongs to the Special Issue Effects of Plant Extracts on Human Health)
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