Sexual Dimorphism in Aquatic Animals

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Animal Genetics and Genomics".

Deadline for manuscript submissions: closed (20 March 2024) | Viewed by 656

Special Issue Editors


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Guest Editor
Key Laboratory of Freshwater Fisheries and Germplasm Resources Utilization, Ministry of Agriculture and Rural Affairs, Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, China
Interests: Cyprinus carpio; Eriocheir sinensis; aquaculture; genetic breeding; sexual dimorphism; SNPs; SSRs; functional genes; signaling pathways

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Guest Editor Assistant
Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences, Wuxi 214081, China
Interests: Cyprinus carpio; crustaceans; sex determination; functional genes; signaling pathways; immunity of aquatic animals

Special Issue Information

Dear Colleagues,

Sexual dimorphism is a significant trait in various fish species and other aquatic animals. Certain traits, such as the growth rate, body size, coloration, morphology, behavior, and ornamentation, may be more pronounced in one gender. Consequently, researchers have implemented genetic breeding programs to create monosex populations to achieve a high ratio of either males or females, which would have enhanced value in aquaculture. Recently, there have been rapid advancements and expanding trends in both fundamental studies and practical applications on sex control worldwide. However, aquaculture animals display a diverse range of sex determination mechanisms, which are affected by genetics, the environment, or a combination of both. Many fish species exhibit a ubiquitous sexual phenotype plasticity, and sex reversal is even a natural part of the life cycle in some species.

For this Special Issue, submissions of research articles, reviews and short communications are welcome. The focus of this Special Issue will be on the understanding of sex determination and gonadal differentiation mechanisms, including molecular mechanisms and environmental effects. It also covers topics such as sex chromosome evolution, reproduction strategies, sexual dimorphism, and approaches for sex control breeding in aquaculture animals, such as the development of sex-linked molecular markers, artificial gynogenesis, artificial sex reversal, application of gene editing technology, etc.

We look forward to receiving your contributions.

Dr. Yongkai Tang
Guest Editor

Dr. Wenrong Feng
Guest Editor Assistant

Manuscript Submission Information

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Keywords

  • fish
  • aquatic animals
  • sexual dimorphism
  • sex determination
  • gonadal differentiation

Published Papers (1 paper)

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Research

12 pages, 4556 KiB  
Article
Developmental Delay and Male-Biased Sex Ratio in esr2b Knockout Zebrafish
by Wei Peng, Yunsheng Zhang, Bolan Song, Pinhong Yang and Liangguo Liu
Genes 2024, 15(5), 636; https://doi.org/10.3390/genes15050636 - 17 May 2024
Viewed by 443
Abstract
The estrogen receptor signaling pathway plays an important role in vertebrate embryonic development and sexual differentiation. There are four major estrogen receptors in zebrafish: esr1, esr2a, esr2b and gper. However, the specific role of different estrogen receptors in zebrafish is [...] Read more.
The estrogen receptor signaling pathway plays an important role in vertebrate embryonic development and sexual differentiation. There are four major estrogen receptors in zebrafish: esr1, esr2a, esr2b and gper. However, the specific role of different estrogen receptors in zebrafish is not clear. To investigate the role of esr2b in zebrafish development and reproduction, this study utilized TALENs technology to generate an esr2b knockout homozygous zebrafish line. The number of eggs laid by esr2b knockout female zebrafish did not differ significantly from that of wild zebrafish. The embryonic development process of wild-type and esr2b knockout zebrafish was observed, revealing a significant developmental delay in the esr2b knockout zebrafish. Additionally, mortality rates were significantly higher in esr2b knockout zebrafish than in their wild-type counterparts at 24 hpf. The reciprocal cross experiment between esr2b knockout zebrafish and wild-type zebrafish revealed that the absence of esr2b resulted in a decline in the quality of zebrafish oocytes, while having no impact on sperm cells. The knockout of esr2b also led to an abnormal sex ratio in the adult zebrafish population, with a female-to-male ratio of approximately 1:7. The quantitative PCR (qPCR) and in situ hybridization results demonstrated a significant downregulation of cyp19ab1b expression in esr2b knockout embryos compared to wild-type embryos throughout development (at 2 dpf, 3 dpf and 4 dpf). Additionally, the estrogen-mediated induction expression of cyp19ab1b was attenuated, while the estradiol-induced upregulated expression of vtg1 was disrupted. These results suggest that esr2b is involved in regulating zebrafish oocyte development and sex differentiation. Full article
(This article belongs to the Special Issue Sexual Dimorphism in Aquatic Animals)
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