Molecular Research on Host-Microbe Interactions

A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Molecular Genetics and Genomics".

Deadline for manuscript submissions: closed (25 April 2023) | Viewed by 2182

Special Issue Editors


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Guest Editor
School of Biological Sciences and Technology, Yangzhou University, Yangzhou, China
Interests: next-generation sequencing data analysis; microbiome; the interaction between the microbiome and the host and the interaction between the microbiome and specific microorganisms (such as pathogenic bacteria)
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Guest Editor
College of Bioscience and Biotechnology, Yangzhou University, Yangzhou, China
Interests: zoonotic pathogens

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Guest Editor
China National Rice Research Institute, Hangzhou, China
Interests: plant-associated pathogens and beneficial bacteria
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is intended to provide new insights into the molecular mechanisms underlying the interactions of bacteria, including pathogenic and symbiotic bacteria, with the host to adapt to host-associated microenvironments. In the host-associated microbiome, certain pathogenic and symbiotic microbes can overcome host- and microbiome-derived selective pressures and form mutualistic relationships with the hosts or cause diseases. By understanding how bacteria respond and adapt to host-associated niches to form mutualistic or pathogenic relationships with the hosts, we can develop novel approaches to manage the bacterial infectious diseases and utilize the beneficial bacteria. Currently, besides the classic forward genetic approaches, omics and associated bioinformatics-aided reverse genetic approaches play an important role in revealing the mechanisms underlying bacteria–host interactions. This Special Issue focuses on studies using genetic and (meta)genomic technologies to explore interactions between pathogenic or symbiotic bacteria and hosts on multiple levels (communities or single cells).

Prof. Dr. Yunzeng Zhang
Dr. Chengkun Zheng
Dr. Lijuan Wu
Guest Editors

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Published Papers (1 paper)

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Research

18 pages, 6320 KiB  
Article
Genomic Insights and Functional Analysis Reveal Plant Growth Promotion Traits of Paenibacillus mucilaginosus G78
by Dan Wang, Verena Poinsot, Wangxi Li, Yusheng Lu, Chong Liu, Yaying Li, Kaizhi Xie, Lili Sun, Chaohong Shi, Huanlong Peng, Wanling Li, Changmin Zhou and Wenjie Gu
Genes 2023, 14(2), 392; https://doi.org/10.3390/genes14020392 - 2 Feb 2023
Cited by 3 | Viewed by 1974
Abstract
Paenibacillus mucilaginosus has widely been reported as a plant growth-promoting rhizobacteria (PGPR). However, the important genomic insights into plant growth promotion in this species remain undescribed. In this study, the genome of P. mucilaginosus G78 was sequenced using Illumina NovaSeq PE150. It contains [...] Read more.
Paenibacillus mucilaginosus has widely been reported as a plant growth-promoting rhizobacteria (PGPR). However, the important genomic insights into plant growth promotion in this species remain undescribed. In this study, the genome of P. mucilaginosus G78 was sequenced using Illumina NovaSeq PE150. It contains 8,576,872 bp with a GC content of 58.5%, and was taxonomically characterized. Additionally, a total of 7337 genes with 143 tRNAs, 41 rRNAs, and 5 ncRNAs were identified. This strain can prohibit the growth of the plant pathogen, but also has the capability to form biofilm, solubilize phosphate, and produce IAA. Twenty-six gene clusters encoding secondary metabolites were identified, and the genotypic characterization indirectly proved its resistant ability to ampicillin, bacitracin, polymyxin and chloramphenicol. The putative exopolysaccharide biosynthesis and biofilm formation gene clusters were explored. According to the genetic features, the potential monosaccharides of its exopolysaccharides for P. mucilaginosus G78 may include glucose, mannose, galactose, fucose, that can probably be acetylated and pyruvated. Conservation of the pelADEFG compared with other 40 Paenibacillus species suggests that Pel may be specific biofilm matrix component in P. mucilaginosus. Several genes relevant to plant growth-promoting traits, i.e., IAA production and phosphate solubilization are well conserved compared with other 40 other Paenibacillus strains. The current study can benefit for understanding the plant growth-promoting traits of P. mucilaginosus as well as its potential application in agriculture as PGPR. Full article
(This article belongs to the Special Issue Molecular Research on Host-Microbe Interactions)
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