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Chitin: Structure, Modifications and Applications
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Chitin: Structure, Modifications and Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Macromolecules".

Deadline for manuscript submissions: closed (15 May 2024) | Viewed by 354

Special Issue Editors

Dr. Artur Valente

E-Mail Website
Guest Editor
Department of Chemistry, University of Coimbra, 3004-535 Coimbra, Portugal
Interests: transport phenomena; surfactants; biopolymers; polysaccharides; supramolecular chemistry
Special Issues, Collections and Topics in MDPI journals
Dr. Xesús Feás

E-Mail Website
Guest Editor
Academy of Veterinary Sciences of Galicia, E-15707 Santiago, Galicia, Spain
Interests: insect; analytical chemistry; biopolymers
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Chitin is a polysaccharide found in a variety of organisms (e.g., arthropods such as shrimps, crabs, etc.). Chitin is used industrially for many different purposes. This includes water and wastewater purification, and as a food additive to stabilize the state of food and pharmaceuticals. However, due to its low solubility and extraction and purification difficulties, introducing nanotechnology, chemical modification and other methods to chitin is urgently needed to achieve better performance. If you conduct scientific research on chitin and have any interesting results, please feel free to share them for this Special Issue of the International Journal of Molecular Sciences. Research and review papers are welcome.

Dr. Artur J. M. Valente
Dr. Xesús Feás
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • chitin
  • nanotechnology
  • chemical modification
  • chitin-based biomaterials

Published Papers (1 paper)

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Research

15 pages, 7777 KiB  
Article
Nanoarchitectonics and Biological Properties of Nanocomposite Thermosensitive Chitosan Hydrogels Obtained with the Use of Uridine 5′-Monophosphate Disodium Salt
by Katarzyna Pieklarz, Grzegorz Galita, Ireneusz Majsterek, Piotr Owczarz and Zofia Modrzejewska
Int. J. Mol. Sci. 2024, 25(11), 5989; https://doi.org/10.3390/ijms25115989 - 30 May 2024
Viewed by 105
Abstract
Currently, an important group of biomaterials used in the research in the field of tissue engineering is thermosensitive chitosan hydrogels. Their main advantage is the possibility of introducing their precursors (sols) into the implantation site using a minimally invasive method—by injection. In this [...] Read more.
Currently, an important group of biomaterials used in the research in the field of tissue engineering is thermosensitive chitosan hydrogels. Their main advantage is the possibility of introducing their precursors (sols) into the implantation site using a minimally invasive method—by injection. In this publication, the results of studies on the new chitosan structures in the form of thermosensitive hydrogels containing graphene oxide as a nanofiller are presented. These systems were prepared from chitosan lactate and chitosan chloride solutions with the use of a salt of pyrimidine nucleotide—uridine 5′-monophosphate disodium salt—as the cross-linking agent. In order to perform the characterization of the developed hydrogels, the sol–gel transition temperature of the colloidal systems was first determined based on rheological measurements. The hydrogels were also analyzed using FTIR spectroscopy and SEM. Biological studies assessed the cytotoxicity (resazurin assay) and genotoxicity (alkaline version of the comet assay) of the nanocomposite chitosan hydrogels against normal human BJ fibroblasts. The conducted research allowed us to conclude that the developed hydrogels containing graphene oxide are an attractive material for potential use as scaffolds for the regeneration of damaged tissues. Full article
(This article belongs to the Special Issue Chitin: Structure, Modifications and Applications)
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