Using Wearable Sensor Technology to Measure Motion Complexity in Infants at High Familial Risk for Autism Spectrum Disorder
Abstract
:1. Introduction
2. Materials and Methods
2.1. Procedures
2.1.1. Quantitative and Standardized Motor Assessment
2.1.2. Developmental Evaluation
2.1.3. Sensor Data
2.1.4. Sensor Data Pre-Processing and Development of the Motion Complexity Index
2.1.5. Evaluation of Motion Complexity Score and Developmental Outcomes
3. Results
3.1. Motion Complexity Score
3.2. Developmental Outcomes
3.3. Relationship of the Motion Complexity Score and Developmental Outcomes
4. Discussion
4.1. Limitations
4.2. Next Steps
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Visit in Months | N | Age (days) | Weight (kg) | Body Length (cm) | Head (cm) | AIMS Percentile |
---|---|---|---|---|---|---|
3 | 4 | 111 (32), (90–158) | 7.375 (1.4), (5.7–8.9) | 63.9 (5.0), (60.1–71.0) | 41.8 (1.5), (39.8–43.2) | 38 (20), (14–67) |
6 | 5 | 198 (29), (180–250) | 8.5 (1.9), (5.9–10.7) | 67.8 (5.3), (59.2–74.0) | 43.9 (1.5), (41.9–45.5) | 41 (27), (5–81) |
9 | 5 | 290 (9), (269–345) | 9.2 (2.0), (6.6–11.5) | 69.3 (3.9), (64.5–73.5) | 45.6 (1.7), (43.6–47.5) | 58 (25), (6–81) |
12 | 5 | 379 (28), (358–429) | 10.3 (2.0), (7.6–12.8) | 74.8 (4.0), (69.0–80.2) | 46.4 (1.23), (44.5–47.9) | 56 (35), (1–90) |
Infant | ADOS Score (18 m) | ADOS Outcome (18 m) | ADOS Score (36 m) | ADOS Outcome (36 m) | MSEL ELC (36 m) | VABS ABC (36 m) |
---|---|---|---|---|---|---|
HR1 | 17 | Autism (moderate-severe concern) | 9 | Autism | 118 | 86 |
HR2 | 18 | Autism (moderate-severe concern) | 12 | Autism | 76 | 70 |
HR3 | 3 | Little to no concern | 6 | Non-spectrum | 113 | 101 |
HR4 | 12 | Mild-moderate concern | 4 | Non-spectrum | 138 | 82 |
HR5 | 1 | Little to no concern | 0 | Non-Spectrum | 116 | 104 |
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Wilson, R.B.; Vangala, S.; Elashoff, D.; Safari, T.; Smith, B.A. Using Wearable Sensor Technology to Measure Motion Complexity in Infants at High Familial Risk for Autism Spectrum Disorder. Sensors 2021, 21, 616. https://doi.org/10.3390/s21020616
Wilson RB, Vangala S, Elashoff D, Safari T, Smith BA. Using Wearable Sensor Technology to Measure Motion Complexity in Infants at High Familial Risk for Autism Spectrum Disorder. Sensors. 2021; 21(2):616. https://doi.org/10.3390/s21020616
Chicago/Turabian StyleWilson, Rujuta B., Sitaram Vangala, David Elashoff, Tabitha Safari, and Beth A. Smith. 2021. "Using Wearable Sensor Technology to Measure Motion Complexity in Infants at High Familial Risk for Autism Spectrum Disorder" Sensors 21, no. 2: 616. https://doi.org/10.3390/s21020616