In Vitro Anti-Inflammatory Activities of Fucoidans from Five Species of Brown Seaweeds
Abstract
:1. Introduction
2. Results and Discussion
2.1. Fucoidan Compositions
2.2. Anti-Inflammatory Activity
2.2.1. The Antiradical and Total Antioxidant Activities
2.2.2. Determination of Mixture Effect
2.2.3. Inhibition of Proteins Denaturation and Membrane Stabilizing Effect
3. Materials and Methods
3.1. Materials
3.2. Extraction Procedures
3.3. Analysis of Fucoidan Composition
3.4. Determination of Antiradical/Antioxidant Activity
3.5. Determination of Mixture Effect
3.6. Inhibition of Proteins Denaturation
3.7. HRBC Membrane Stabilization
3.8. Statistical Analysis
4. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Seaweed Source | Sample Code | Method of Extraction | Yield (% DW) | Total Neutral Carbohydrate (g/100 g DW) | Sulfate (g/100 g DW) | Total Polyphenols Content (PhE/g DW) |
---|---|---|---|---|---|---|
Saccharina japonica | SJ | - | - | 48.4 ± 2.5 | 28.1 ± 0.2 | 10.1 ± 0.1 |
F. vesiculosus | FV1 | I | 22.3 | 64.1 ± 0.6 | 25.9 ± 2.6 | 139.6 ± 0.7 |
F. vesiculosus | FV2 | II | 6.6 | 62.6 ± 0.4 | 25.4 ± 1.0 | 13.3 ± 0.3 |
F. vesiculosus | FV3 | III | 8.2 | 53.7 ± 0.6 | 20.9 ± 1.5 | 132.2 ± 0.7 |
F. distichus | FD1 | I | 15.4 | 50.7 ± 1.1 | 17.6 ± 0.3 | 72.8 ± 0.6 |
F. serratus | FS1 | I | 13.6 | 45.5 ± 1.5 | 15.1 ± 0.1 | 64.0 ± 0.4 |
A. nodosum | AN1 | I | 16.1 | 49.9 ± 0.1 | 19.2 ± 0.1 | 62.4 ± 0.2 |
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Obluchinskaya, E.D.; Pozharitskaya, O.N.; Shikov, A.N. In Vitro Anti-Inflammatory Activities of Fucoidans from Five Species of Brown Seaweeds. Mar. Drugs 2022, 20, 606. https://doi.org/10.3390/md20100606
Obluchinskaya ED, Pozharitskaya ON, Shikov AN. In Vitro Anti-Inflammatory Activities of Fucoidans from Five Species of Brown Seaweeds. Marine Drugs. 2022; 20(10):606. https://doi.org/10.3390/md20100606
Chicago/Turabian StyleObluchinskaya, Ekaterina D., Olga N. Pozharitskaya, and Alexander N. Shikov. 2022. "In Vitro Anti-Inflammatory Activities of Fucoidans from Five Species of Brown Seaweeds" Marine Drugs 20, no. 10: 606. https://doi.org/10.3390/md20100606
APA StyleObluchinskaya, E. D., Pozharitskaya, O. N., & Shikov, A. N. (2022). In Vitro Anti-Inflammatory Activities of Fucoidans from Five Species of Brown Seaweeds. Marine Drugs, 20(10), 606. https://doi.org/10.3390/md20100606