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Marine Drugs
Volume 22
Issue 6
10.3390/md22060256
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Review

Revolutionizing Cardiovascular Health with Nano Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach

by
Richa Gill
1,
Mashael Al-Badr
1,
Mohammad Alghouti
2,
Nura Adam Mohamed
3,
Haissam Abou-Saleh
4,* and
Md Mizanur Rahman
1,*
1
Biological Science Program, Department of Biological and Environmental Sciences, College of Arts and Sciences, Qatar University, Doha P.O. Box 2713, Qatar
2
Environmental Science Program, Department of Biological and Environmental Sciences, College of Arts and Sciences, Qatar University, Doha P.O. Box 2713, Qatar
3
Biomedical Research Center, Qatar University, Doha P.O. Box 2713, Qatar
4
Biomedical Sciences Department, College of Health Sciences, Qatar University, Doha P.O. Box 2713, Qatar
*
Authors to whom correspondence should be addressed.
Mar. Drugs 2024, 22(6), 256; https://doi.org/10.3390/md22060256
Submission received: 17 April 2024 / Revised: 27 May 2024 / Accepted: 28 May 2024 / Published: 30 May 2024
(This article belongs to the Special Issue Value-Added Products from Marine Fishes)
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Abstract

Omega-3 polyunsaturated fatty acids (ω-3 PUFAs) offer diverse health benefits, such as supporting cardiovascular health, improving cognitive function, promoting joint and musculoskeletal health, and contributing to healthy aging. Despite their advantages, challenges like oxidation susceptibility, low bioavailability, and potential adverse effects at high doses persist. Nanoparticle encapsulation emerges as a promising avenue to address these limitations while preserving stability, enhanced bioavailability, and controlled release. This comprehensive review explores the therapeutic roles of omega-3 fatty acids, critically appraising their shortcomings and delving into modern encapsulation strategies. Furthermore, it explores the potential advantages of metal–organic framework nanoparticles (MOF NPs) compared to other commonly utilized nanoparticles in improving the therapeutic effectiveness of omega-3 fatty acids within drug delivery systems (DDSs). Additionally, it outlines future research directions to fully exploit the therapeutic benefits of these encapsulated omega-3 formulations for cardiovascular disease treatment.
Keywords: omega-3 fatty acids; cardiovascular disease; nanoparticle encapsulation; metal–organic framework; drug delivery systems omega-3 fatty acids; cardiovascular disease; nanoparticle encapsulation; metal–organic framework; drug delivery systems

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MDPI and ACS Style

Gill, R.; Al-Badr, M.; Alghouti, M.; Mohamed, N.A.; Abou-Saleh, H.; Rahman, M.M. Revolutionizing Cardiovascular Health with Nano Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach. Mar. Drugs 2024, 22, 256. https://doi.org/10.3390/md22060256

AMA Style

Gill R, Al-Badr M, Alghouti M, Mohamed NA, Abou-Saleh H, Rahman MM. Revolutionizing Cardiovascular Health with Nano Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach. Marine Drugs. 2024; 22(6):256. https://doi.org/10.3390/md22060256

Chicago/Turabian Style

Gill, Richa, Mashael Al-Badr, Mohammad Alghouti, Nura Adam Mohamed, Haissam Abou-Saleh, and Md Mizanur Rahman. 2024. "Revolutionizing Cardiovascular Health with Nano Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach" Marine Drugs 22, no. 6: 256. https://doi.org/10.3390/md22060256

APA Style

Gill, R., Al-Badr, M., Alghouti, M., Mohamed, N. A., Abou-Saleh, H., & Rahman, M. M. (2024). Revolutionizing Cardiovascular Health with Nano Encapsulated Omega-3 Fatty Acids: A Nano-Solution Approach. Marine Drugs, 22(6), 256. https://doi.org/10.3390/md22060256

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