Marine Bacteriocins: An Evolutionary Gold Mine to Payoff Antibiotic Resistance
Abstract
:1. Introduction
2. Diverse Bacteriocins from Marine Bacteria
2.1. Leaderless Bacteriocins
2.1.1. Piscicocin
2.1.2. Mundticin KS
2.1.3. Divercin V41
2.1.4. Divergicin M35
2.1.5. BaCf3
2.1.6. Sonorensin
2.1.7. CAMT6
2.2. Lanthipeptides
2.2.1. Nisin Z
2.2.2. Subtilomycin
2.2.3. Viridisin
2.2.4. Thalassomonasin
2.2.5. Formicin
2.2.6. Mathermycin
2.2.7. Prochlorosins
3. Evolutionary Diversity of Marine Bacteriocins
4. Challenges and Future Directions
5. Conclusions
Author Contributions
Funding
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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AMP | Class | Producer Bacteria | Source | Activity Spectrum | References |
---|---|---|---|---|---|
Leaderless | |||||
Piscicocins V1a Piscicocin CS526 | Class IIa | C. piscicola V1 C. piscicola CS526 | Fresh fish, smoked and marinated fish, fish intestinal tract | L. monocytogenes L. sake L. curvatus L. plantarum L. mesenteroıdes P. acidilactici E. faecalis | [12,14] |
Mundticin KS | Class IIa | E. mundtii NFRI 7393 | Silverside (Odontesthes platensis) | E. faecium L. plantarum L. lactis L. curvatus L. monocytogenes P. pentosaceus S. thermophiles S. pyogenes P. aeruginosa S. putrefaciens | [15,16] |
Diversin V41 | Class IIa | C. divergens V41 | Fish viscera | Gram-positive bacteria | [12,17] |
Divergicin M35 | Class IIa | C. divergens M35 | Frozen smoked mussels | L. monocytogenes | [18] |
BaCf3 | Not assigned | B. amyloliquefaciens BTSS3 | Deep-sea shark (Centroscyllium fabricii) | Bacillus sp. S. warnie M. luteus G. stearothermophilus S. typhimurium C. perfringens E. faecalis | [19] |
Sonorensin | Not assigned | B. sonorensis MT93 | Marine | L. monocytogenes V. vulnificus B. subtilis S. aureus P. aeruginosa E. coli | [20] |
CAMT6 | Not assigned | E. durans YQ-6 | Marine fish (Larimichthys polyactis) | S. aureus B. subtilis B. equi B. cereus S. haemolyticus P. acnes S.paratyphi V. parahaemolyticus P. foulis E. aerogenes L. monocytogenes | [21] |
Lanthipeptides | |||||
Nisin Z | Type I lantibiotic | L. lactic NIZO 22186 | Marine fish (Olive flounder) | S. iniae L. garvieae | [22,23] |
Subtilomycin | Type I lantibiotic | B. subtilis MMA7 | Marine sponge (Haliclona simulans) | Bacillus sp. Clostridium L. monocytogenes S. aureus P. aeruginosa VISA MRSA Candida sp. | [24] |
Viridisin | Type I lantibiotic | T. viridans XOM25 | Marine | Not determined | [25] |
Thalassomonasin A and B | Type I lantibiotic | T. actiniarum NBRC 104231 | Marine | B. subtilis S. aureus M. luteus E. coli P. aeruginosa | [26] |
Formicin | Type II lantibiotic | B. paralicheniformis APC 1576 | Atlantic mackerel (Scomber scombrus) | L. monocytogenes S. aureus S. mutans C. difficile Clostridia Enterococcus sp. | [27] |
Mathermycin | Type II lantibiotic | Marinactinospora thermotolerans SCSIO 00652 | Marine sediments | B. subtilis | [28] |
Prochlorosins | Type II lantibiotic | Prochlorococcus Synechococcus | Marine | Not determined | [29] |
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Baindara, P.; Dinata, R.; Mandal, S.M. Marine Bacteriocins: An Evolutionary Gold Mine to Payoff Antibiotic Resistance. Mar. Drugs 2024, 22, 388. https://doi.org/10.3390/md22090388
Baindara P, Dinata R, Mandal SM. Marine Bacteriocins: An Evolutionary Gold Mine to Payoff Antibiotic Resistance. Marine Drugs. 2024; 22(9):388. https://doi.org/10.3390/md22090388
Chicago/Turabian StyleBaindara, Piyush, Roy Dinata, and Santi M. Mandal. 2024. "Marine Bacteriocins: An Evolutionary Gold Mine to Payoff Antibiotic Resistance" Marine Drugs 22, no. 9: 388. https://doi.org/10.3390/md22090388